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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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29 recruiting trials

for Locally Advanced Hepatocellular Carcinoma

FOLFOX Combined With Durvalumab (MEDI4736), Bevacizumab, and Stereotactic Body Radiotherapy in Sequential Treatment of Potentially Resectable Locally Advanced Hepatocellular Carcinoma NCT07012798Phase 21 site📍 Tianjin Tianjin Medical University Cancer Institute and Hospital · Tests: Durvalumab, Bevacizumab, HAIC of FOLFOX A Phase I Study of CREPT-618 in Locally Advanced HCC NCT07364357Phase 11 site📍 Beijing Cancer Institute and Hospital, Chinese Academy of Medical S… · Tests: gene therapy A Phase 1 Study of TGI-5 as Monotherapy and in Combination With Nivolumab in Subjects With Locally Advanced/Metastatic Solid Tumors NCT07376707Phase 11 site📍 Shanghai Hefei TG ImmunoPharma Co., Ltd. · Tests: TGI-5 Ipilimumab and Nivolumab With SBRT in Locally Advanced Hepatocellular Cancer NCT07075120Phase 12 sites📍 Honolulu📍 Honolulu University of Hawaii · Tests: Ipilimumab and Nivolumab, Stereotactic Body Radiotherapy (SBRT) Safety and Preliminary Anti-Tumor Activity of TYRA-430 in Advanced Hepatocellular Carcinoma and Other Solid Tumors With Activating FGF/FGFR Pathway Aberrations NCT06915753Phase 116 sites📍 Los Angeles📍 San Francisco📍 Stanford Tyra Biosciences, Inc · Tests: TYRA-430 Safety, PK and Efficacy of QXL138AM in Patients With Solid Tumors and Multiple Myeloma NCT06582017Phase 111 sites📍 Los Angeles📍 Los Angeles📍 Los Angeles Nammi Therapeutics Inc · Tests: QXL138AM Injection every 2 weeks by IV Infusion Radioembolization as a Spearhead Treatment of Hepatocellular Carcinoma With Localized Portal Vein Tumor Thrombosis NCT06166576Phase 25 sites📍 Ilsan📍 Seongnam-si📍 Seoul Seoul National University Hospital · Tests: Ablative radioembolization Comparison of SBRT and SIRT With Combination IO for Locally-advanced, Unresectable HCCs (BIIRTH) NCT07293468Phase 2, Phase 31 site📍 Hong Kong Tuen Mun Hospital · Tests: Transarterial chemoembolization (TACE), Stereotactic Body Radiation Therapy (SBRT), SIRT Yttrium-90, Atezolizumab &… FOG-001 in Locally Advanced or Metastatic Solid Tumors NCT05919264Phase 1, Phase 233 sites📍 Phoenix📍 Scottsdale📍 Tucson Parabilis Medicines, Inc. · Tests: FOG-001, mFOLFOX-6, Nivolumab, Trifluridine/tipiracil, Bevacizumab First in Human Study of SIM0610 in Solid Tumors NCT07348211Phase 17 sites📍 Chongqing📍 Harbin📍 Shenyang Jiangsu Simcere Pharmaceutical Co., Ltd. · Tests: SIM0610 for Injection, SIM0610 for Injection A Study of TTI-101 as Monotherapy and in Combination in Participants With Locally Advanced or Metastatic, and Unresectable Hepatocellular Carcinoma NCT05440708Phase 1, Phase 221 sites📍 Birmingham📍 La Jolla📍 Los Angeles Tvardi Therapeutics, Incorporated · Tests: TTI-101, Pembrolizumab, Atezolizumab, Bevacizumab Evaluation of Skin Tests in Biotherapy Allergies NCT06971848NA1 site📍 Angers University Hospital, Angers · Tests: Drug skin tests (investigating hypersensitivity to a biotherapy) Personalized DC Vaccine for Postoperative Cancer NCT04147078Phase 11 site📍 Chengdu Sichuan University · Tests: DC vaccine subcutaneous administration A Study of Therapeutic Drug Monitoring-Based Atezolizumab Dosing NCT06066138Phase 11 site📍 Bethesda National Cancer Institute (NCI) · Tests: Atezolizumab A Study to Explore the Reasonable Dosage and Evaluate the Efficacy, Safety and Tolerability of HLX10 and HLX04 with or Without HLX53 in Untreated, Locally Advanced or Metastatic Hepatocellular Carcinoma Patients. NCT06349980Phase 21 site📍 Shanghai Shanghai Henlius Biotech · Tests: HLX53 (1000mg), HLX53 (2000mg), HLX10, HLX04, Placebo A Study of Oral 7HP349 (Alintegimod) in Combination With Ipilimumab Followed by Nivolumab Monotherapy NCT06362369Phase 1, Phase 25 sites📍 Aurora📍 Lake Mary📍 Lebanon 7 Hills Pharma, LLC · Tests: Alintegimod, Ipilimumab, Nivolumab Fostrox Plus Lenvatinib vs Lenvatinib in Advanced Hepatocellular Carcinoma After First-line Immunotherapy NCT07493668Phase 21 site📍 Seongnam-si CHA University · Tests: Fostrox, Lenvatinib A First-in-human Study to Learn About the Safety of BAY 3547926 and How Well it Works in Participants With Advanced Liver Cancer NCT06764316Phase 136 sites📍 Dothan📍 Duarte📍 Orlando Bayer · Tests: BAY 3547926, BAY 3547922, BAY 3713391, BAY 3713389 Olanzapine for the Management of Cancer Associated Appetite Loss in Patients With Advanced Esophagogastric, Hepatopancreaticobiliary, Colorectal or Lung Cancer NCT05705492Phase 21 site📍 Portland OHSU Knight Cancer Institute · Tests: Olanzapine, Placebo Administration, Questionnaire Administration A Study on the Prevalence of Clinically Useful Mutations in Solid Tumor Characterized by Next Generation Sequencing Methods on Liquid Biopsy Analysis (POPCORN) NCT06028724n/a1 site📍 Aviano Centro di Riferimento Oncologico - Aviano Comparison of In-Home Versus In-Clinic Administration of Subcutaneous Nivolumab Through Cancer CARE (Connected Access and Remote Expertise) Beyond Walls (CCBW) Program NCT06265285Phase 21 site📍 Jacksonville Mayo Clinic · Tests: Home Health Encounter, Nivolumab, Patient Monitoring, Questionnaire Administration Symbiotic-GI-13: A Study to Learn About Study Medicine Called PF-08634404 as a Single Treatment and Combination Treatment in Adult Participants With a Liver Cancer Called Hepatocellular Carcinoma, That is Too Advanced to be Removed by Surgery and May Have Spread to Other Parts of the Body. NCT07227012Phase 1, Phase 260 sites📍 Irvine📍 Irvine📍 Irvine Pfizer · Tests: PF-08634404, Ipilimumab Study of RP2 in Combination With Second-line Therapy in Patients With Locally Advanced or Metastatic HCC NCT05733598Phase 212 sites📍 Beverly Hills📍 La Jolla📍 Miami Replimune, Inc. · Tests: RP2, Bevacizumab, Atezolizumab, Durvalumab, RP2 Monotherapy Radioembolization With Intra-arterial Angiotensin II to Improve Tumor-absorbed Dose (RADIANT) NCT07312292Phase 21 site📍 Utrecht Niek Wijnen · Tests: Angiotensin II (Giapreza®), Yttrium-90 radioembolization A Phase II Clinical Study to Evaluate HLX43 in Patients With Locally Advanced or Metastatic HCC Failed or Intolerance to Standard Therapy NCT06742892Phase 21 site📍 Hunan Shanghai Henlius Biotech · Tests: HLX43 DOSE 1, HLX43 DOSE 2, HLX43 DOSE 3 Atezolizumab in Combination With a Multi-Kinase Inhibitor for the Treatment of Unresectable, Locally Advanced, or Metastatic Liver Cancer NCT05168163Phase 216 sites📍 Scottsdale📍 Jacksonville📍 Weston Academic and Community Cancer Research United · Tests: Atezolizumab, Cabozantinib, Lenvatinib Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors NCT05269381Phase 1, Phase 21 site📍 Jacksonville Mayo Clinic · Tests: Cyclophosphamide, Neoantigen Peptide Vaccine, Pembrolizumab, Sargramostim, Biospecimen Collection Holmium-166 Transarterial Radioembolization for the Treatment of Hepatocellular Carcinoma NCT06873269n/a1 site📍 Brussels Universitair Ziekenhuis Brussel · Tests: Baseline assessment, holmium-166 radioembolization, Follow-up phase Biomarker-Guided Allogeneic Single-Target or Dual-Target CAR-NK Cell Therapy for Advanced Solid Tumors NCT07410494Phase 1, Phase 21 site📍 Beijing Essen Biotech · Tests: EB-SELECT Single-Target CAR-NK Cells, Dual-Target Antigen-Selected CAR-NK
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