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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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20 recruiting trials

for Locally Advanced Oral Squamous Cell Carcinoma

Testing the Addition of Ipatasertib to Usual Chemotherapy and Radiation for Head and Neck Cancer NCT05172245Phase 118 sites📍 Tampa📍 Chicago📍 Fairway National Cancer Institute (NCI) · Tests: Biopsy Procedure, Biospecimen Collection, Cisplatin, Computed Tomography, Ipatasertib Thermotherapy for Head and Neck Cancer Patients NCT07690618Phase 11 site📍 Rotterdam Erasmus Medical Center · Tests: Thermotherapy, Radiotherapy, Concurrent chemoradiation Neoadjuvant Immunochemotherapy for LAOSCC NCT06258811Phase 31 site📍 Shanghai Lai-ping Zhong · Tests: albumin paclitaxel, cispatin, tislelizumab Testing the Addition of Chemotherapy or Chemo-Immunotherapy to the Usual Surgery for Advanced Head and Neck Cancer NCT07195734Phase 2115 sites📍 Tucson📍 Tucson📍 Irvine National Cancer Institute (NCI) · Tests: Biospecimen Collection, Carboplatin, Cemiplimab, Cisplatin, Computed Tomography Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist) NCT04198766Phase 1, Phase 242 sites📍 Duarte📍 Glendale📍 Los Angeles Inhibrx Biosciences, Inc · Tests: INBRX-106 - Hexavalent OX40 agonist antibody, pembrolizumab 200 mg, pembrolizumab 400 mg, Carboplatin AUC-5, Carboplati… Association Between Tinnitus and Hearing Loss in Locally Advanced Head and Neck Cancer Treated by Radiotherapy Alone or With Chemotherapy: a Prospective and Multicenter Study NCT05946577n/a1 site📍 Paris Assistance Publique - Hôpitaux de Paris Tirilizumab with Albumin-bound Paclitaxel and Cisplatin for Locally Advanced Resectable Oral Squamous Cell Carcinoma NCT06470217Phase 21 site📍 Shanghai Shanghai Ninth People's Hospital Affiliated to Shanghai Jia… · Tests: tirilizumab with albumin-bound paclitaxel and cisplatin, surgery A Bidirectional Observational Clinical Study of NAIC in the Treatment of Tumor Regression Patterns in LA-OSCC and LA-OPSCC NCT07133958n/a1 site📍 Guangzhou Zhujiang Hospital Sintilimab Plus Chemotherapy as Neoadjuvant and Adjuvant Treatment for Locally Advanced Oral Squamous Cell Carcinoma NCT07371611Phase 31 site📍 Guangzhou Qunxing Li,MD · Tests: Sintilimab plus nab-paclitaxel and platinum-based chemotherapy, Radical surgery combined with radiotherapy or chemoradi… Objective Response Rate of Ivonescimab With Chemotherapy in Locally Advanced Resectable Oral and Oropharyngeal Squamous Cell Carcinoma NCT07686575n/a2 sites📍 Guangzhou📍 Guangzhou Zhujiang Hospital · Tests: Ivonescimab（AK112，a PD-1/VEGF bispecific antibody） Prospective Cohort Study on Oral Microbiome Changes in Patients With Locally Advanced Oral Squamous Cell Carcinoma Following Neoadjuvant Chemoimmunotherapy NCT07111455n/a1 site📍 Guangzhou Zhujiang Hospital Neoadjuvant Anti-PD-1 and TP Versus TPF on Pathological Response in OSCC NCT05125055Phase 2, Phase 31 site📍 Shanghai Shanghai Jiao Tong University School of Medicine · Tests: Toripalimab (anti-programmed death-1 inhibitor), Albumin paclitaxel, Cisplatin, Docetaxel, 5-Fluorouracil Neoadjuvant Personalized Anti-PD-1 and Anti-VEGFR Therapy in OSCC Patients NCT05069857Phase 21 site📍 Shanghai Shanghai Jiao Tong University School of Medicine · Tests: Camrelizumab (anti-PD-1 inhibitor), Apatinib (anti-VEGFR inhibitor) d-Limonene +Radiation +PlatinumBasedChemo for Xerostomia Prevention in LocallyAdvanced HNSCC NCT04392622Phase 11 site📍 Stanford Stanford University · Tests: D-Limonene Gelcaps, Intensity modulated radiotherapy (IMRT), Cisplatin, Xerostomia questionnaire BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study NCT05136196Phase 2232 sites📍 Phoenix📍 Little Rock📍 Beverly Hills National Cancer Institute (NCI) · Tests: Biopsy Procedure, Biospecimen Collection, Cabozantinib S-malate, Computed Tomography, Magnetic Resonance Imaging Iparomlimab and Tuvonralimab With With Cetuximab in Resectable OSCC NCT07882888Phase 21 site📍 Shanghai Shanghai Ninth People's Hospital Affiliated to Shanghai Jia… · Tests: iparomlimab and tuvonralimab combined with cetuximab VMD-928 Monotherapy and in Combination With Pembrolizumab to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma NCT03556228Phase 1, Phase 215 sites📍 Santa Rosa📍 Hartford📍 Washington D.C. VM Oncology, LLC · Tests: VMD-928 100 mg Tablet, VMD-928 Tablet and Pembrolizumab (200 mg) Neoadjuvant Treatment of Tislelizumab Combined Chemotherapy for Locally Advanced Oral Squamous Cell Carcinoma ：A Single-arm, Prospective, Phase II Trial NCT05862168Phase 21 site📍 Hangzhou Weijia Fang, MD · Tests: Tislelizumab, Albumin paclitaxel, Cisplatin, 5-Fluorouracil Exploratory Clinical Trial of Oral Paclitaxel Plus Radiotherapy in Patients With Locally Advanced Unresectable Esophageal Squamous Cell Carcinoma NCT07435454Phase 21 site📍 Nanjing Jiangsu Cancer Institute & Hospital · Tests: oral paclitaxel+radiotherapy First-in-Human Study of ATX-295, an Oral Inhibitor of KIF18A, as Monotherapy and in Combination With Anticancer Therapy in Patients With Advanced or Metastatic Solid Tumors, Including Ovarian Cancer NCT06799065Phase 1, Phase 211 sites📍 Aurora📍 Sarasota📍 Detroit Accent Therapeutics · Tests: ATX-295, ATX-295 and bevacizumab (or biosimilar)
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