๐ŸŒ EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

๐Ÿงช

Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

Know your stage or your test results (such as EGFR, HER2 or BRCA)? Match trials to your own profile - nothing you type is saved.

๐ŸŽฏ Match trials to me

30 recruiting trials

for Locally Advanced Urothelial Carcinoma

DBC-664 in Adult Patients With Solid Tumors NCT07705035Phase 16 sites๐Ÿ“ Denver๐Ÿ“ Grand Rapids๐Ÿ“ East Brunswick Duboce Biopharmaceuticals, Inc. ยท Tests: DBC-664 Phase II Study of Trastuzumab Rezetecan or in Combination With Adebrelimab in HER2-Expressing Locally Advanced or Metastatic Urothelial Carcinoma (la/mUC) NCT07241793Phase 26 sites๐Ÿ“ Guangzhou๐Ÿ“ Guangzhou๐Ÿ“ Guangzhou Sun Yat-sen University ยท Tests: Adebrelimab, Trastuzumab Rezetecan A Study to Evaluate 9MW2821 Versus Chemotherapy in Subjects With Previously Treated Locally Advanced or Metastatic Urothelial Cancer NCT06196736Phase 31 site๐Ÿ“ Shanghai Mabwell (Shanghai) Bioscience Co., Ltd. ยท Tests: 9MW2821, Chemotherapy FORAGER-1: A Study of Vepugratinib (LY3866288; LOXO-435) in Participants With Cancer With a Change in a Gene Called FGFR3 NCT05614739Phase 182 sites๐Ÿ“ Tucson๐Ÿ“ Duarte๐Ÿ“ Los Angeles Eli Lilly and Company ยท Tests: Vepugratinib, Pembrolizumab, enfortumab vedotin, Trastuzumab Deruxtecan, Midazolam Enfortumab Vedotin and Pembrolizumab With Cystectomy and/or Ureterectomy for Locally Advanced or Metastatic Bladder and Upper Urothelial Tract Cancer, CAST-AI Trial NCT06764095Phase 41 site๐Ÿ“ Rochester Mayo Clinic ยท Tests: Biospecimen Collection, Computed Tomography, Cystectomy, Enfortumab Vedotin, Local Therapy A Study of SI-B003 and BL-B01D1+SI-B003 in Patients With Locally Advanced or Metastatic Urothelial Carcinoma and Other Solid Tumors NCT05965856Phase 21 site๐Ÿ“ Shanghai Sichuan Baili Pharmaceutical Co., Ltd. ยท Tests: BL-B01D1, SI-B003 Safety, PK and Efficacy of QXL138AM in Patients With Solid Tumors and Multiple Myeloma NCT06582017Phase 111 sites๐Ÿ“ Los Angeles๐Ÿ“ Los Angeles๐Ÿ“ Los Angeles Nammi Therapeutics Inc ยท Tests: QXL138AM Injection every 2 weeks by IV Infusion A Study of RC48-ADC Combined With Toripalimab For First-line Treatment of Urothelial Carcinoma NCT05302284Phase 32 sites๐Ÿ“ Beijing๐Ÿ“ Beijing RemeGen Co., Ltd. ยท Tests: RC48-ADC, Toripalimab, Gemcitabine, Cisplatin, Carboplatin Study of Datopotamab Deruxtecan Plus Carboplatin or Cisplatin Versus Gemcitabine Plus Carboplatin or Cisplatin in Participants With Locally Advanced or Metastatic Urothelial Carcinoma NCT07129993Phase 2, Phase 3100 sites๐Ÿ“ Fullerton๐Ÿ“ Glendale๐Ÿ“ La Jolla Daiichi Sankyo ยท Tests: Dato-DXd, Carboplatin, Cisplatin, Gemcitabine EV + Toripalimab vs GC as Neoadjuvant Therapy in Locally Advanced/High-Risk MIBC NCT07647289Phase 21 site๐Ÿ“ Beijing Peking University Third Hospital ยท Tests: enfortumab vedotin (EV), Toripalimab, Gemcitabine (Chemotherapy), Cisplatin Clofarabine Therapy in Locally Advanced or Metastatic Urothelial Carcinoma NCT07034053Phase 1, Phase 21 site๐Ÿ“ Vienna Ekaterina Laukhtina ยท Tests: Clofarabine A Phase III Study of SHR-A2102 Versus Investigator-selected Therapy in Advanced Urothelial Carcinoma NCT06738251Phase 31 site๐Ÿ“ Beijing Shanghai Hengrui Pharmaceutical Co., Ltd. ยท Tests: SHR-A2102 for Injection, Docetaxel Injection, Paclitaxel Injection, Gemcitabine Hydrochloride for Injection, Pemetrexedโ€ฆ A Study of [225Ac]Ac-AKY-1189 in Patients With Solid Tumors NCT07020117Phase 114 sites๐Ÿ“ Duarte๐Ÿ“ Irvine๐Ÿ“ Miami Aktis Oncology, Inc. ยท Tests: [225Ac]Ac-AKY-1189 (therapeutic), [64Cu]Cu-AKY-1189 (imaging) Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytrudaยฎ) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist) NCT04198766Phase 1, Phase 242 sites๐Ÿ“ Duarte๐Ÿ“ Glendale๐Ÿ“ Los Angeles Inhibrx Biosciences, Inc ยท Tests: INBRX-106 - Hexavalent OX40 agonist antibody, pembrolizumab 200 mg, pembrolizumab 400 mg, Carboplatin AUC-5, Carboplatiโ€ฆ A Clinical Trial of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) to Treat Urothelial Cancer (MK-2870-031) NCT07419295Phase 3107 sites๐Ÿ“ Washington D.C.๐Ÿ“ Atlanta๐Ÿ“ Baltimore Merck Sharp & Dohme LLC ยท Tests: Sacituzumab tirumotecan, Vinflunine, Docetaxel, Paclitaxel, Rescue medications for sacituzumab tirumotecan Consolidative Local Therapy (CLT) in Oligo-metastatic Urothelial Carcinoma NCT07048457Phase 22 sites๐Ÿ“ New Haven๐Ÿ“ Madison Yale University ยท Tests: Radical cystectomy Clinical Trial of YH32364 in Patients With Locally Advanced or Metastatic EGFR Overexpressing Solid Tumors NCT06975410Phase 1, Phase 24 sites๐Ÿ“ Seoul๐Ÿ“ Seoul๐Ÿ“ Seoul Yuhan Corporation ยท Tests: YH32364 Chemotherapy and Sequential Immunotherapy for Locally Advanced Urothelial Cancer NCT05600127Phase 24 sites๐Ÿ“ Nijmegen๐Ÿ“ 's-Hertogenbosch๐Ÿ“ Breda Erasmus Medical Center ยท Tests: Avelumab Enfortumab Vedotin, Pembrolizumab and Quemliclustat for the Treatment of Unresectable Locally Advanced and Metastatic Urothelial Cancer NCT07667335Phase 1, Phase 21 site๐Ÿ“ Seattle Fred Hutchinson Cancer Center ยท Tests: Quemliclustat, Biospecimen Collection, Computed Tomography, Enfortumab Vedotin, Magnetic Resonance Imaging Study of AU-007, A Monoclonal Antibody That Binds to IL-2 and Inhibits IL-2Rฮฑ Binding, in Patients With Unresectable Locally Advanced or Metastatic Cancer NCT05267626Phase 1, Phase 217 sites๐Ÿ“ Miami๐Ÿ“ Grand Rapids๐Ÿ“ Minneapolis Aulos Bioscience, Inc. ยท Tests: AU-007, Aldesleukin, Avelumab, Nivolumab Combined Postoperative Radiotherapy With Kidney Sparing Surgery for Locally Advanced High-risk Ureteral Cancer NCT06120387n/a2 sites๐Ÿ“ Beijing๐Ÿ“ Beijing Xuesong Li ยท Tests: Radical surgery, Kidney sparing surgery+Postoperative radiotheray A Study to Assess Safety, Tolerability and Imaging Characteristics of [68Ga]Ga-DPI-4452 and to Assess Safety, Tolerability, and Efficacy of [177Lu]Lu-DPI-4452 in Participants With Unresectable Locally Advanced or Metastatic Solid Tumors NCT05706129Phase 1, Phase 210 sites๐Ÿ“ Melbourne๐Ÿ“ Sydney๐Ÿ“ Clermont-Ferrand Lumara Bio Oncologics GmbH ยท Tests: [68Ga]Ga-DPI-4452, [177Lu]Lu-DPI-4452 TALazoparib and Avelumab as Maintenance Therapy in Platinum-Sensitive Metastatic or Locally Advanced URothelial Carcinoma NCT04678362Phase 214 sites๐Ÿ“ Angers๐Ÿ“ Besanรงon๐Ÿ“ Caen Centre Francois Baclesse ยท Tests: Talazoparib + Avelumab 9MW2821 + Toripalimab vs 9MW2821 for 1st Line Locally Advanced or Metastatic Urothelial Carcinoma NCT06823427Phase 22 sites๐Ÿ“ Changsha๐Ÿ“ Nanjing Mabwell (Shanghai) Bioscience Co., Ltd. ยท Tests: 9MW2821, Toripalimab (JS001 ) Safety and Tolerability of TNG462 in Patients With MTAP-deleted Solid Tumors NCT05732831Phase 1, Phase 226 sites๐Ÿ“ Palo Alto๐Ÿ“ Grand Junction๐Ÿ“ Lake Mary Tango Therapeutics, Inc. ยท Tests: TNG462, Pembrolizumab A Trial of SHR-A2102 With Adebrelimab in Locally Advanced or Metastatic Urothelial Carcinoma NCT07393542Phase 31 site๐Ÿ“ Beijing Suzhou Suncadia Biopharmaceuticals Co., Ltd. ยท Tests: SHR-A2102 and Adebrelimab, Gemcitabine and cisplatin / carboplatin Trastuzumab in Combination With Serplulimab and Chemotherapy for the Treatment of HER2-overexpressing Unresectable Locally Advanced or Metastatic Biliary Tract Cancer or Urothelial Carcinoma After Failure of Standard Therapy NCT07506057Phase 21 site๐Ÿ“ Shenyang Xiujuan Qu ยท Tests: Trastuzumab+Serplulimab Symbiotic-GU-06: A Study to Learn About PF-08634404 Alone or In Combination With Enfortumab Vedotin in Urothelial Cancer NCT07421700Phase 1, Phase 2184 sites๐Ÿ“ Fayetteville๐Ÿ“ Rogers๐Ÿ“ Springdale Pfizer ยท Tests: PF-08634404, Enfortumab Vedotin Comparison of In-Home Versus In-Clinic Administration of Subcutaneous Nivolumab Through Cancer CARE (Connected Access and Remote Expertise) Beyond Walls (CCBW) Program NCT06265285Phase 21 site๐Ÿ“ Jacksonville Mayo Clinic ยท Tests: Home Health Encounter, Nivolumab, Patient Monitoring, Questionnaire Administration Circulating and Urine Tumor DNA Dynamics Predict Minimal Residual Disease and Recurrence Risk in Locally Advanced Upper Tract Urothelial Carcinoma NCT05595408n/a1 site๐Ÿ“ Shanghai RenJi Hospital ยท Tests: Adjuvant chemotherapy, adjuvant immunotherapy
๐Ÿ›ก๏ธ

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it โ€” not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use ยท Privacy