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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Locally Advanced or Metastatic Urothelial Carcinoma

A Study of MRG002 Versus Investigator's Choice of Chemotherapy in the Treatment of Patients With HER2-positive Unresectable Advanced or Metastatic Urothelial Cancer NCT05754853Phase 31 site๐Ÿ“ Beijing Shanghai Miracogen Inc. ยท Tests: MRG002, Docetaxel Injection, Paclitaxel Injection, Gemcitabine Hydrochloride for Injection, Pemetrexed Disodium Injectiโ€ฆ DBC-664 in Adult Patients With Solid Tumors NCT07705035Phase 16 sites๐Ÿ“ Denver๐Ÿ“ Grand Rapids๐Ÿ“ East Brunswick Duboce Biopharmaceuticals, Inc. ยท Tests: DBC-664 Phase II Study of Trastuzumab Rezetecan or in Combination With Adebrelimab in HER2-Expressing Locally Advanced or Metastatic Urothelial Carcinoma (la/mUC) NCT07241793Phase 26 sites๐Ÿ“ Guangzhou๐Ÿ“ Guangzhou๐Ÿ“ Guangzhou Sun Yat-sen University ยท Tests: Adebrelimab, Trastuzumab Rezetecan A Study to Evaluate 9MW2821 Versus Chemotherapy in Subjects With Previously Treated Locally Advanced or Metastatic Urothelial Cancer NCT06196736Phase 31 site๐Ÿ“ Shanghai Mabwell (Shanghai) Bioscience Co., Ltd. ยท Tests: 9MW2821, Chemotherapy FORAGER-1: A Study of Vepugratinib (LY3866288; LOXO-435) in Participants With Cancer With a Change in a Gene Called FGFR3 NCT05614739Phase 182 sites๐Ÿ“ Tucson๐Ÿ“ Duarte๐Ÿ“ Los Angeles Eli Lilly and Company ยท Tests: Vepugratinib, Pembrolizumab, enfortumab vedotin, Trastuzumab Deruxtecan, Midazolam Enfortumab Vedotin and Pembrolizumab With Cystectomy and/or Ureterectomy for Locally Advanced or Metastatic Bladder and Upper Urothelial Tract Cancer, CAST-AI Trial NCT06764095Phase 41 site๐Ÿ“ Rochester Mayo Clinic ยท Tests: Biospecimen Collection, Computed Tomography, Cystectomy, Enfortumab Vedotin, Local Therapy A Study of SI-B003 and BL-B01D1+SI-B003 in Patients With Locally Advanced or Metastatic Urothelial Carcinoma and Other Solid Tumors NCT05965856Phase 21 site๐Ÿ“ Shanghai Sichuan Baili Pharmaceutical Co., Ltd. ยท Tests: BL-B01D1, SI-B003 Safety, PK and Efficacy of QXL138AM in Patients With Solid Tumors and Multiple Myeloma NCT06582017Phase 111 sites๐Ÿ“ Los Angeles๐Ÿ“ Los Angeles๐Ÿ“ Los Angeles Nammi Therapeutics Inc ยท Tests: QXL138AM Injection every 2 weeks by IV Infusion A Study of RC48-ADC Combined With Toripalimab For First-line Treatment of Urothelial Carcinoma NCT05302284Phase 32 sites๐Ÿ“ Beijing๐Ÿ“ Beijing RemeGen Co., Ltd. ยท Tests: RC48-ADC, Toripalimab, Gemcitabine, Cisplatin, Carboplatin Study of Datopotamab Deruxtecan Plus Carboplatin or Cisplatin Versus Gemcitabine Plus Carboplatin or Cisplatin in Participants With Locally Advanced or Metastatic Urothelial Carcinoma NCT07129993Phase 2, Phase 3100 sites๐Ÿ“ Fullerton๐Ÿ“ Glendale๐Ÿ“ La Jolla Daiichi Sankyo ยท Tests: Dato-DXd, Carboplatin, Cisplatin, Gemcitabine Clofarabine Therapy in Locally Advanced or Metastatic Urothelial Carcinoma NCT07034053Phase 1, Phase 21 site๐Ÿ“ Vienna Ekaterina Laukhtina ยท Tests: Clofarabine A Phase III Study of SHR-A2102 Versus Investigator-selected Therapy in Advanced Urothelial Carcinoma NCT06738251Phase 31 site๐Ÿ“ Beijing Shanghai Hengrui Pharmaceutical Co., Ltd. ยท Tests: SHR-A2102 for Injection, Docetaxel Injection, Paclitaxel Injection, Gemcitabine Hydrochloride for Injection, Pemetrexedโ€ฆ A Study of [225Ac]Ac-AKY-1189 in Patients With Solid Tumors NCT07020117Phase 114 sites๐Ÿ“ Duarte๐Ÿ“ Irvine๐Ÿ“ Miami Aktis Oncology, Inc. ยท Tests: [225Ac]Ac-AKY-1189 (therapeutic), [64Cu]Cu-AKY-1189 (imaging) Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytrudaยฎ) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist) NCT04198766Phase 1, Phase 242 sites๐Ÿ“ Duarte๐Ÿ“ Glendale๐Ÿ“ Los Angeles Inhibrx Biosciences, Inc ยท Tests: INBRX-106 - Hexavalent OX40 agonist antibody, pembrolizumab 200 mg, pembrolizumab 400 mg, Carboplatin AUC-5, Carboplatiโ€ฆ Consolidative Local Therapy (CLT) in Oligo-metastatic Urothelial Carcinoma NCT07048457Phase 22 sites๐Ÿ“ New Haven๐Ÿ“ Madison Yale University ยท Tests: Radical cystectomy Clinical Trial of YH32364 in Patients With Locally Advanced or Metastatic EGFR Overexpressing Solid Tumors NCT06975410Phase 1, Phase 24 sites๐Ÿ“ Seoul๐Ÿ“ Seoul๐Ÿ“ Seoul Yuhan Corporation ยท Tests: YH32364 Study of AU-007, A Monoclonal Antibody That Binds to IL-2 and Inhibits IL-2Rฮฑ Binding, in Patients With Unresectable Locally Advanced or Metastatic Cancer NCT05267626Phase 1, Phase 217 sites๐Ÿ“ Miami๐Ÿ“ Grand Rapids๐Ÿ“ Minneapolis Aulos Bioscience, Inc. ยท Tests: AU-007, Aldesleukin, Avelumab, Nivolumab A Study to Assess Safety, Tolerability and Imaging Characteristics of [68Ga]Ga-DPI-4452 and to Assess Safety, Tolerability, and Efficacy of [177Lu]Lu-DPI-4452 in Participants With Unresectable Locally Advanced or Metastatic Solid Tumors NCT05706129Phase 1, Phase 210 sites๐Ÿ“ Melbourne๐Ÿ“ Sydney๐Ÿ“ Clermont-Ferrand Lumara Bio Oncologics GmbH ยท Tests: [68Ga]Ga-DPI-4452, [177Lu]Lu-DPI-4452 TALazoparib and Avelumab as Maintenance Therapy in Platinum-Sensitive Metastatic or Locally Advanced URothelial Carcinoma NCT04678362Phase 214 sites๐Ÿ“ Angers๐Ÿ“ Besanรงon๐Ÿ“ Caen Centre Francois Baclesse ยท Tests: Talazoparib + Avelumab 9MW2821 + Toripalimab vs 9MW2821 for 1st Line Locally Advanced or Metastatic Urothelial Carcinoma NCT06823427Phase 22 sites๐Ÿ“ Changsha๐Ÿ“ Nanjing Mabwell (Shanghai) Bioscience Co., Ltd. ยท Tests: 9MW2821, Toripalimab (JS001 ) Safety and Tolerability of TNG462 in Patients With MTAP-deleted Solid Tumors NCT05732831Phase 1, Phase 226 sites๐Ÿ“ Palo Alto๐Ÿ“ Grand Junction๐Ÿ“ Lake Mary Tango Therapeutics, Inc. ยท Tests: TNG462, Pembrolizumab A Trial of SHR-A2102 With Adebrelimab in Locally Advanced or Metastatic Urothelial Carcinoma NCT07393542Phase 31 site๐Ÿ“ Beijing Suzhou Suncadia Biopharmaceuticals Co., Ltd. ยท Tests: SHR-A2102 and Adebrelimab, Gemcitabine and cisplatin / carboplatin Trastuzumab in Combination With Serplulimab and Chemotherapy for the Treatment of HER2-overexpressing Unresectable Locally Advanced or Metastatic Biliary Tract Cancer or Urothelial Carcinoma After Failure of Standard Therapy NCT07506057Phase 21 site๐Ÿ“ Shenyang Xiujuan Qu ยท Tests: Trastuzumab+Serplulimab Symbiotic-GU-06: A Study to Learn About PF-08634404 Alone or In Combination With Enfortumab Vedotin in Urothelial Cancer NCT07421700Phase 1, Phase 2184 sites๐Ÿ“ Fayetteville๐Ÿ“ Rogers๐Ÿ“ Springdale Pfizer ยท Tests: PF-08634404, Enfortumab Vedotin Cabozantinib in Combination With Enfortumab Vedotin for Locally Advanced or Metastatic Urothelial Cancer NCT04878029Phase 11 site๐Ÿ“ Atlanta Emory University ยท Tests: Cabozantinib S-malate, Enfortumab Vedotin, Quality-of-Life Assessment, Questionnaire Administration A Study of Ivonescimab in Combination With Enfortumab Vedotin vs Pembrolizumab in Combination With Enfortumab Vedotin in Metastatic Urothelial Carcinoma NCT07815665Phase 2, Phase 37 sites๐Ÿ“ Phoenix๐Ÿ“ Los Angeles๐Ÿ“ Washington D.C. Summit Therapeutics ยท Tests: Ivonescimab Dose 1, enfortumab vedotin (EV), Pembrolizumab, Ivonescimab Dose 2, Ivonescimab RP3D AVENTINE-1: Study of AVZO-1418 as a Single Agent and in Combination Therapy in Patients With Locally Advanced or Metastatic Solid Tumors (AVZO-1418-1001) NCT07038343Phase 1, Phase 227 sites๐Ÿ“ Gilbert๐Ÿ“ Los Angeles๐Ÿ“ Los Angeles Avenzo Therapeutics, Inc. ยท Tests: AVZO-1418, Combination Agent 1, Combination Agent 2 A Study of DR-0202 in Patients With Locally Advanced or Metastatic, Relapsed or Refractory Carcinomas NCT06999187Phase 110 sites๐Ÿ“ Denver๐Ÿ“ Orlando๐Ÿ“ Sarasota Dren Bio ยท Tests: DR-0202 Gemcitabine and Carboplatin After Progression on Enfortumab Vedotin and Pembrolizumab in Advanced/Metastatic Urothelial Carcinoma NCT07043972Phase 22 sites๐Ÿ“ Philadelphia๐Ÿ“ Philadelphia Fox Chase Cancer Center ยท Tests: Gemcitabine, Carboplatin Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors NCT05269381Phase 1, Phase 21 site๐Ÿ“ Jacksonville Mayo Clinic ยท Tests: Cyclophosphamide, Neoantigen Peptide Vaccine, Pembrolizumab, Sargramostim, Biospecimen Collection
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