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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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22 recruiting trials

for Locally Recurrent Head and Neck Cancer

MRG003 Induction and Capecitabine Maintenance With PD-1 in Locally Recurrent NPC NCT07331428Phase 21 site๐Ÿ“ Fuzhou Fujian Cancer Hospital ยท Tests: MRG003, Tislelizumab, Capecitabine Study With ABBV-CLS-484 in Participants With Locally Advanced or Metastatic Tumors NCT04777994Phase 130 sites๐Ÿ“ Tucson๐Ÿ“ New Haven๐Ÿ“ Baltimore Calico Life Sciences LLC ยท Tests: ABBV-CLS-484, Vascular Endothelial Growth Factor Receptor (VEGFR) Tyrosine Kinase Inhibitor (TKI), Programmed Cell Deatโ€ฆ Becotatug Vedotin Combined With a PD-1 Inhibitor in the Treatment of Locally Advanced Recurrent Nasopharyngeal Carcinoma. NCT07781358Phase 21 site๐Ÿ“ Shanghai Hongmeng Yu ยท Tests: Becotatug Vedotin, PD-1 / PD-L1 monoclonal antibody Carbon Ion Re-Radiotherapy in Patients With Recurrent or Progressive Locally Advanced Head-and-Neck Cancer NCT04185974NA2 sites๐Ÿ“ Heidelberg๐Ÿ“ Marburg University Hospital Heidelberg ยท Tests: C12 re-irradiation, Photon re-irradiation Toripalimab Plus Concurrent Chemo-radiotherapy for Unresectable Locally Recurrent Nasopharyngeal Carcinoma NCT04453813Phase 36 sites๐Ÿ“ Guangzhou๐Ÿ“ Guangzhou๐Ÿ“ Shaoguan Sun Yat-sen University ยท Tests: Toripalimab plus concurrent chemo-radiotherapy, Concurrent chemo-radiotherapy Testing the Addition of Chemotherapy or Chemo-Immunotherapy to the Usual Surgery for Advanced Head and Neck Cancer NCT07195734Phase 2115 sites๐Ÿ“ Tucson๐Ÿ“ Tucson๐Ÿ“ Irvine National Cancer Institute (NCI) ยท Tests: Biospecimen Collection, Carboplatin, Cemiplimab, Cisplatin, Computed Tomography Window of Opportunity in Preserving Laryngeal Function Trial NCT07423078Phase 21 site๐Ÿ“ Pittsburgh Matthew Spector ยท Tests: Toripalimab, Carboplatin, Cisplatin, Paclitaxel, Radiation Therapy Association Between Health Care Provider (HCP)-Assessed ECOG Performance Status (PS) and Overall Survival, and Objectively Measure of Physical Activity (PA) Levels in Advance-cancer Patients" NCT01365169NA1 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Exercise Intervention, Health Telemonitoring, Health Telemonitoring, Health Telemonitoring, Health Telemonitoring Neoadjuvant vs Adjuvant in Locally Advanced Recurrent NPC NCT06235203Phase 37 sites๐Ÿ“ Shanghai๐Ÿ“ Fuzhou๐Ÿ“ Nanning Eye & ENT Hospital of Fudan University ยท Tests: endoscopic surgery, Neoadjuvant therapy,Toripalimab Injection and Gemcitabine based therapy, Adjuvant therapy in experiโ€ฆ PD-1 Inhibitor Plus Chemotherapy Followed by Immediate Versus Selective Re-irradiation for Locally Advanced Recurrent NPC NCT07332247Phase 21 site๐Ÿ“ Guangzhou Sun Yat-sen University ยท Tests: Selective re-irradiation, Immediate re-irradiation Cemiplimab and Cetuximab Prior Salvage Surgery in Patients With Recurrent Oral Cavity and HPV-negative Oropharyngeal Squamous Cell Carcinoma NCT06448026Phase 21 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Cemiplimab, Cetuximab RW Study of Adjuvant Radiotherapy in Locally Advanced Thyroid Cancer NCT06524167n/a1 site๐Ÿ“ Shanghai Fudan University ยท Tests: adjuvant radiotherapy Concurrent Chemotherapy for Recurrent T3/T4 Nasopharyngeal Carcinoma NCT04136886Phase 31 site๐Ÿ“ Guangzhou Sun Yat-sen University ยท Tests: Cisplatin, IMRT Losartan, Pembrolizumab and Stereotactic Body Radiation Therapy for the Treatment of Patients With Locally Recurrent, Refractory or Oligometastatic Head and Neck Squamous Cell Carcinoma NCT06211335Phase 12 sites๐Ÿ“ Sacramento๐Ÿ“ Aurora University of California, Davis ยท Tests: Losartan, Pembrolizumab, Stereotactic Body Radiation Therapy A Study of BL-B01D1 in Combination With Tislelizumab ยฑ5-Fluorouracil Versus Platinum-Based Chemotherapy Plus Tislelizumab as First-line Treatment in Patients With Unresectable, Locally Advanced Recurrent or Metastatic Esophageal Squamous Cell Carcinoma(PANKU-Esophagus02) NCT07554456Phase 2, Phase 31 site๐Ÿ“ Beijing Sichuan Baili Pharmaceutical Co., Ltd. ยท Tests: BL-B01D1, Tislelizumab, 5-Fluorouracil, Cisplatin, Paclitaxel Salvage Brachytherapy and Hyperthermia for Recurrent H&N-tumours NCT03238378NA1 site๐Ÿ“ Erlangen University of Erlangen-Nรผrnberg Medical School ยท Tests: Brachytherapy, Hyperthermia Study of Larotinib in Unresectable Advanced or Recurrent Esophageal Cancer NCT04415853Phase 31 site๐Ÿ“ Beijing Sunshine Lake Pharma Co., Ltd. ยท Tests: Lerotinib, Irinotecan/Tegafur Combining Immunotherapy Salvage Surgery & IORT Tx Persistent/Recurrent Head & Neck Cancer NCT04754321Phase 11 site๐Ÿ“ Columbus Ohio State University Comprehensive Cancer Center ยท Tests: External Beam Radiation Therapy, Intraoperative Radiation Therapy, Pembrolizumab, Quality-of-Life Assessment, Salvage Sโ€ฆ Comparison of In-Home Versus In-Clinic Administration of Subcutaneous Nivolumab Through Cancer CARE (Connected Access and Remote Expertise) Beyond Walls (CCBW) Program NCT06265285Phase 21 site๐Ÿ“ Jacksonville Mayo Clinic ยท Tests: Home Health Encounter, Nivolumab, Patient Monitoring, Questionnaire Administration A Study to Evaluate the Safety and Efficacy of A2B395, an Allogeneic Logic-gated CAR T, in Participants With Solid Tumors That Express EGFR and Have Lost HLA-A*02 Expression NCT06682793Phase 1, Phase 210 sites๐Ÿ“ Gilbert๐Ÿ“ La Jolla๐Ÿ“ Los Angeles A2 Biotherapeutics Inc. ยท Tests: A2B395, xT CDx with HLA-LOH assay BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study NCT05136196Phase 2232 sites๐Ÿ“ Phoenix๐Ÿ“ Little Rock๐Ÿ“ Beverly Hills National Cancer Institute (NCI) ยท Tests: Biopsy Procedure, Biospecimen Collection, Cabozantinib S-malate, Computed Tomography, Magnetic Resonance Imaging Becotatug Vedotin Combined With Pucotenlimab for Locally Recurrent Resectable Head and Neck Squamous Cell Carcinoma NCT07632339Phase 21 site๐Ÿ“ Shanghai Shanghai Ninth People's Hospital Affiliated to Shanghai Jiaโ€ฆ ยท Tests: Becotatug Vedotin combined with Pucotenlimab, surgery
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