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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

Know your stage or your test results (such as EGFR, HER2 or BRCA)? Match trials to your own profile - nothing you type is saved.

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17 recruiting trials

for Locally Recurrent Rectal Cancer

SBRT + PD-1 Antibody in Unresectable Locally Recurrent Rectal Cancer（SPARKLE） NCT06767007Phase 21 site📍 Guangzhou Sixth Affiliated Hospital, Sun Yat-sen University · Tests: Stereotactic Body Radiation Therapy (SBRT), PD1, Chemotherapy Fluorescence Image Guided Surgery Followed by Intraoperative Photodynamic Therapy for Improving Local Tumor Control in Patients With Locally Advanced or Recurrent Colorectal Cancer NCT06307548Phase 1, Phase 21 site📍 Buffalo Roswell Park Cancer Institute · Tests: Aminolevulinic Acid, Biospecimen Collection, Computed Tomography, Fluorescence-Guided Surgery, Magnetic Resonance Imagi… Surgery Plus Chemo Versus Chemoradiotherapy Followed by Surgery Plus Chemo for Locally Recurrent Rectal Cancer NCT04288999Phase 345 sites📍 Chiba📍 Gifu📍 Hidaka National Cancer Center Hospital East · Tests: Chemotherapy, Preoperative radiotherapy, Procedure Hypofractionated Radiotherapy Combined With NALIRIF, PD-1 Antibody in Locally Recurrent Rectal Cancer(NOVELTY-R) NCT07183865Phase 21 site📍 Shanghai Fudan University · Tests: radiotherapy, Irinotecan Hydrochloride Liposome, 5-FU, Leucovorin, SG001 Association Between Health Care Provider (HCP)-Assessed ECOG Performance Status (PS) and Overall Survival, and Objectively Measure of Physical Activity (PA) Levels in Advance-cancer Patients" NCT01365169NA1 site📍 Houston M.D. Anderson Cancer Center · Tests: Exercise Intervention, Health Telemonitoring, Health Telemonitoring, Health Telemonitoring, Health Telemonitoring Neoadjuvant Chemotherapy and PD-1 Inhibitor for Locally Advanced Rectal Cancer（CONTROL-01） NCT06647680Phase 21 site📍 Qingdao The Affiliated Hospital of Qingdao University · Tests: Receive the experimental combination of drugs (chemoradiation (Oxaliplatin and Capecitabine) + PD-1 inhibitor (Tisleliz… Hypofractionated Radiotherapy Plus Immunotherapy Versus Conventional Radiotherapy in Locally Recurrent Rectal Cancer NCT06928584Phase 21 site📍 Shanghai Fudan University · Tests: Conventional Radiotherapy, Capecitabine, 5-fluorouracil, folinic acid, Oxaliplatin Induction Chemotherapy for Locally Recurrent Rectal Cancer NCT04389086Phase 314 sites📍 Ghent📍 Amsterdam📍 Amsterdam Catharina Ziekenhuis Eindhoven · Tests: Combination drug, Chemoradiotherapy, Surgery locally recurrent rectal cancer Laparoscopic Robot-assisted Pelvic Exenteration for Pelvic Primary and Recurrent Cancers NCT05186493NA1 site📍 Oslo Oslo University Hospital · Tests: robot-assisted total pelvic exenteration Radiotherapy Dose Escalation for Non-operative Management of Unresectable Locally Recurrent Rectal Cancer (STEP-UP) NCT07721181NA6 sites📍 Maastricht📍 Arnhem📍 Arnhem Heike M.U. Peulen · Tests: SBRT, Hyperfractionated chemo-reirradiation, Full-course chemoradiotherapy Comparison of In-Home Versus In-Clinic Administration of Subcutaneous Nivolumab Through Cancer CARE (Connected Access and Remote Expertise) Beyond Walls (CCBW) Program NCT06265285Phase 21 site📍 Jacksonville Mayo Clinic · Tests: Home Health Encounter, Nivolumab, Patient Monitoring, Questionnaire Administration A Study to Evaluate the Safety and Efficacy of A2B395, an Allogeneic Logic-gated CAR T, in Participants With Solid Tumors That Express EGFR and Have Lost HLA-A*02 Expression NCT06682793Phase 1, Phase 210 sites📍 Gilbert📍 La Jolla📍 Los Angeles A2 Biotherapeutics Inc. · Tests: A2B395, xT CDx with HLA-LOH assay A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression NCT06051695Phase 1, Phase 212 sites📍 Gilbert📍 La Jolla📍 Los Angeles A2 Biotherapeutics Inc. · Tests: A2B694, A2B543, xT CDx with HLA-LOH Assay Stereotactic Body Radiation Therapy for Unresectable Locally Recurrent Rectal Cancer NCT07297004Phase 21 site📍 Guangzhou Sixth Affiliated Hospital, Sun Yat-sen University · Tests: Stereotactic Body Radiation Therapy (SBRT) A Dose-Expansion Trial of Intravenous HNF4α srRNA for Unresectable or Metastatic Colorectal Cancer NCT07050394EARLY Phase 11 site📍 Shanghai Shanghai Changzheng Hospital · Tests: CD-GA-102 Using Rectal Hydrogel Spacer for Salvage SABR in Prostate Cancer NCT05597852NA1 site📍 Toronto Sunnybrook Health Sciences Centre · Tests: SpaceOAR Biomarker-Guided Allogeneic Single-Target or Dual-Target CAR-NK Cell Therapy for Advanced Solid Tumors NCT07410494Phase 1, Phase 21 site📍 Beijing Essen Biotech · Tests: EB-SELECT Single-Target CAR-NK Cells, Dual-Target Antigen-Selected CAR-NK
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