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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Lymphoma Cns

Combination Regimen of Teniposide, PD-1 Monoclonal Antibody and Selinixor for Patients With Relapsed or Refractory PCNSL NCT07074470NA1 site๐Ÿ“ Suzhou The First Affiliated Hospital of Soochow University ยท Tests: Induction therapy-2 cycles of VPX (Teniposide, PD-1 monoclonal antibody plus Selinixor), Consolidation therapy with ASCโ€ฆ Orelabrutinib Combined With Pemetrexed For Relapsed/Refractory Central Nervous System Lymphoma NCT05209620Phase 21 site๐Ÿ“ Zhengzhou Henan Cancer Hospital ยท Tests: ICP-022, Pemetrexed Q702 for the Treatment of Patients With Hematologic Malignancies NCT06712810Phase 12 sites๐Ÿ“ Scottsdale๐Ÿ“ Rochester Mayo Clinic ยท Tests: Axl/Mer/CSF1R Inhibitor Q702, Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy, Computed Tomography ASCT With TEAM Conditioning for Lymphoma With High Risk of CNS Relapse NCT07481669Phase 21 site๐Ÿ“ Hangzhou Second Affiliated Hospital, Zhejiang University, School of โ€ฆ ยท Tests: TEAM regimen (thiotepa, etoposide, cytarabine and melphalan) Intracerebroventricular Administration of CD19-CAR T Cells (CD19CAR-CD28-CD3zeta-EGFRt-expressing Tn/Mem T-lymphocytes) for the Treatment of Central Nervous System Lymphoma NCT05625594Phase 11 site๐Ÿ“ Duarte City of Hope Medical Center ยท Tests: Aspiration, Biospecimen Collection, Catheterization, CD19CAR-CD28-CD3zeta-EGFRt-expressing Tn/mem T-lymphocytes, Computโ€ฆ Orelabrutinib Combined With Teniposide, Rituximab and Methotrexate for Newly Diagnosed PCNSL NCT07185373Phase 2, Phase 315 sites๐Ÿ“ Beijing๐Ÿ“ Beijing๐Ÿ“ Chengdu Huashan Hospital ยท Tests: Teniposide, Orelabrutinib, MTX, Rituximab (R), Dexamethasone CLIMB: CNS Lymphoma Imaging and Molecular Biomarkers Study NCT05828628n/a1 site๐Ÿ“ Sutton Royal Marsden NHS Foundation Trust Rituximab-Methotrexate-Temozolomide-Thiotepa (RMTT) Regimen As First-line Therapy for PCNS DLBCL NCT06832267NA1 site๐Ÿ“ Hangzhou Zhejiang Cancer Hospital ยท Tests: Rituximab-Methotrexate-Temozolomide-Thiotepa (RMTT) The OPAL Study: AVM0703 for Treatment of Lymphoid Malignancies NCT04329728Phase 1, Phase 211 sites๐Ÿ“ Duarte๐Ÿ“ Los Angeles๐Ÿ“ Los Angeles AVM Biotechnology Inc ยท Tests: AVM0703 Study of Lenalidomide/Rituximab Maintenance for Transplantation Ineligible Patients With PCNSL. NCT04627753Phase 21 site๐Ÿ“ Seoul Kim, Seok Jin ยท Tests: Rituximab, lenalidomide MT2021-08T Cell Receptor Alpha/Beta Depletion PBSC Transplantation for Heme Malignancies NCT05735717Phase 21 site๐Ÿ“ Minneapolis Masonic Cancer Center, University of Minnesota ยท Tests: Fludarabine, Busulfan, Melphalan, Rituximab, Levetiracetam Acalabrutinib Maintenance for the Treatment of Patients With Large B-cell Lymphoma NCT05256641Phase 1, Phase 23 sites๐Ÿ“ Los Angeles๐Ÿ“ Sacramento๐Ÿ“ Oklahoma City Jonsson Comprehensive Cancer Center ยท Tests: Acalabrutinib B-cell Mature Non-Hodgkin's Lymphoma Treatment Protocol in Children and Adolescents 2021 NCT05518383Phase 41 site๐Ÿ“ Moscow Federal Research Institute of Pediatric Hematology, Oncologโ€ฆ ยท Tests: Cyclophosphamide, Cytarabine, Dexamethasone, Etoposide, Ifosfamide, Methotrexate, Cyclophosphamide, Cytarabine, Dexametโ€ฆ [90Y]Y-PTT Endoradiotherapy in CNS Lymphoma Patients NCT06132737Phase 1, Phase 22 sites๐Ÿ“ Munich๐Ÿ“ Essen Pentixapharm AG ยท Tests: [90Y]Y-PentixaTher The DANCEREX Proof-of-Concept Study for Chronic Neurological Disorders NCT06112639NA3 sites๐Ÿ“ Brescia๐Ÿ“ Messina๐Ÿ“ Milan Fondazione Don Carlo Gnocchi ETS ยท Tests: DANCEREX-DTx, Multidimensional dance-based program, Educational Program Dolutegravir Versus Dolutegravir in Combination With Tenofovir for the Treatment of HTLV-1 Infection NCT07555431Phase 21 site๐Ÿ“ Salvador Carlos Brites ยท Tests: Combination of Dolutegravir + Tenofovir DF for treatment of HTLV-1 infection, Dolutegravir (DTG) Tafasitamab Plus Lenalidomide in Relapsed CNS Lymphoma NCT05351593Phase 1, Phase 21 site๐Ÿ“ San Francisco James Rubenstein ยท Tests: Tafasitamab, Lenalidomide A Study of Circulating Tumor DNA (ctDNA) Testing for People With B-Cell Lymphoma NCT06736613Phase 27 sites๐Ÿ“ Basking Ridge๐Ÿ“ Middletown๐Ÿ“ Montvale Memorial Sloan Kettering Cancer Center ยท Tests: Cerebral Spinal Fluid ctDNA Autologous Adipose-Derived Mesenchymal Stem Cells for Chronic Traumatic Brain Injury NCT05951777Phase 22 sites๐Ÿ“ Houston๐Ÿ“ San Antonio Hope Biosciences LLC ยท Tests: Autologous HB-adMSCs, Normal Saline A Study of CAR-T Cells Therapy for Patients With Relapsed and/or Refractory Central Nervous System Hematological Malignancies NCT04532203EARLY Phase 11 site๐Ÿ“ Hangzhou Zhejiang University ยท Tests: CAR-T cells, Ommaya Reservoir Lenalidomide Maintenance Treatment in Patients With Primary Central Nervous System Lymphoma NCT05260619Phase 21 site๐Ÿ“ Seongnam-si Seoul National University Bundang Hospital ยท Tests: lenalidomide Fasudil Trial for Treatment of Early Alzheimer's Disease (FEAD) NCT06362707Phase 26 sites๐Ÿ“ Tromsรธ๐Ÿ“ Oslo๐Ÿ“ Haugesund Helse Stavanger HF ยท Tests: Fasudil, Placebo Chronic CED of TPT for Recurrent Malignant Glioma NCT06666712Phase 11 site๐Ÿ“ New York Jeffrey N. Bruce ยท Tests: Topotecan Registry of an Integrated Longitudinal Multimodal Biospecimen Biobank for Primary CNS Lymphoma in China NCT07842835n/a3 sites๐Ÿ“ Beijing๐Ÿ“ Shandong๐Ÿ“ Tianjin Xiaohui Ren ยท Tests: High-dose methotrexate-based therapy, Bruton tyrosine kinase inhibitor-based therapy Fourth-gen CAR T Cells Targeting CD19/CD22 for Highly Resistant B-cell Lymphoma/Leukemia (PMBCL/CNS-BCL). NCT06213636Phase 1, Phase 21 site๐Ÿ“ Beijing Essen Biotech ยท Tests: CD19/CD22-CAR T cells R-PMDT Regimen in Newly Diagnosed PCNSL NCT07604987Phase 21 site๐Ÿ“ Tianjin Zou Dehui ยท Tests: R-PMDT A Study of RNA-lipid Particle (RNA-LP) Vaccines for Newly Diagnosed Pediatric High-Grade Gliomas (pHGG) and Adult Glioblastoma (GBM) NCT04573140Phase 12 sites๐Ÿ“ Washington D.C.๐Ÿ“ Gainesville University of Florida ยท Tests: Autologous total tumor mRNA and pp65 full length (fl) lysosomal associated membrane protein (LAMP) mRNA loaded DOTAP liโ€ฆ Cognitive Screening Made Easy for PCPs - Administrative Supplement NCT06928298NA3 sites๐Ÿ“ Austin๐Ÿ“ Austin๐Ÿ“ San Antonio University of Texas at Austin ยท Tests: RACS app Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford NCT01793168n/a2 sites๐Ÿ“ Sioux Falls๐Ÿ“ Sydney Sanford Health CA-4948-101: Open-Label, Dose Escalation and Expansion Trial of Emavusertib (CA-4948) in Relapsed or Refractory Primary Central Nervous System Lymphoma (R/R PCNSL) NCT03328078Phase 1, Phase 245 sites๐Ÿ“ Phoenix๐Ÿ“ Phoenix๐Ÿ“ Duarte Curis, Inc. ยท Tests: Emavusertib, Ibrutinib
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