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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

Know your stage or your test results (such as EGFR, HER2 or BRCA)? Match trials to your own profile - nothing you type is saved.

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30 recruiting trials

for MTA

Orelabrutinib Combined With Pemetrexed For Relapsed/Refractory Central Nervous System Lymphoma NCT05209620Phase 21 site📍 Zhengzhou Henan Cancer Hospital · Tests: ICP-022, Pemetrexed Efficacy and Safety of Ivonescimab Plus Pemetrexed and Platinum-Based Chemotherapy in Advanced Malignant Pleural Mesothelioma NCT07885319Phase 1, Phase 23 sites📍 Shanghai📍 Shanghai📍 Chengdu Ruijin Hospital · Tests: Ivonescimab Combined With Chemotherapy A Study Evaluating Sotorasib Platinum Doublet Combination Versus Pembrolizumab Platinum Doublet Combination as a Front-Line Therapy in Participants With Stage IV or Advanced Stage IIIB/C Nonsquamous Non-Small Cell Lung Cancers (CodeBreaK 202) NCT05920356Phase 3424 sites📍 Santa Barbara📍 Newark📍 Coral Springs Amgen · Tests: Sotorasib, Pembrolizumab Study to Evaluate Adverse Events and Efficacy of Intravenous (IV) Telisotuzumab Adizutecan in Combination With a PD-1 Immune Checkpoint Inhibitor in Adult Participants With Advanced or Metastatic Non-Squamous NSCLC With No Prior Treatment for Advanced Disease, and No Actionable Genomic Alterations NCT06772623Phase 1, Phase 2126 sites📍 Phoenix📍 Fullerton📍 Oxnard AbbVie · Tests: Telisotuzumab Adizutecan, Budigalimab, Pembrolizumab, Pembrolizumab, Carboplatin Neoadjuvant IBI308, Bevacizumab, Plus Pemetrexed and Carboplatin Followed by Surgery in Unresectable Stage III NSCLC NCT03872661Phase 21 site📍 Guangzhou Sun Yat-sen University · Tests: IBI308, Bevacizumab, Pemetrexed, Carboplatin, Thoracic surgery Safety, Efficacy, and Pharmacokinetics of BNT327 in Combination With Chemotherapy and Other Investigational Agents for Lung Cancer (ROSETTA Lung-02) NCT06712316Phase 2, Phase 3365 sites📍 Birmingham📍 Anchorage📍 Concord BioNTech SE · Tests: Pumitamig, Pembrolizumab, Carboplatin, Pemetrexed, Paclitaxel Integration of the PD-L1 Inhibitor Atezolizumab and WT1/DC Vaccination Into Platinum/Pemetrexed-based First-line Treatment for Epithelioid Malignant Pleural Mesothelioma NCT05765084Phase 1, Phase 23 sites📍 Edegem📍 Ghent📍 Sint-Niklaas University Hospital, Antwerp · Tests: Dendritic cell vaccination, Atezolizumab, Platinum/pemetrexed based chemotherapy Efficacy and Resistance Mechanisms of IP in NSCLC With Leptomeningeal Metastases NCT06440954Phase 21 site📍 Changsha Hunan Province Tumor Hospital · Tests: Intrathecal pemetrexed BMS-986504 in Combination With Pemetrexed for the Treatment of Metastatic Solid Tumors With MTAP Deletion NCT07594626Phase 1, Phase 21 site📍 Chicago Northwestern University · Tests: Biospecimen Collection, Computed Tomography, Pemetrexed, PRMT5 Inhibitor BMS-986504 Intrathecal Injection Pemetrexed And Bevacizumab in Patients With Leptomeningeal Metastases in NSCLC NCT06663306Phase 11 site📍 Shanghai Shanghai Chest Hospital · Tests: Pemetrexed, Bevacizumab JAB-21822 Combined With JAB-3312 Compared SOC in the First Line for Treatment of Advanced Non-small Cell Lung Cancer With KRAS p.G12C Mutation NCT06416410Phase 337 sites📍 Hefei📍 Beijing📍 Beijing Allist Pharmaceuticals, Inc. · Tests: JAB-21822, Tislelizumab, JAB-3312, Pemetrexed, Carboplatin A Study to Evaluate the Combination of Platinum-pemetrexed Based Chemotherapy Plus Lorlatinib in ALK Positive Non-Small Cell Lung Cancer (NSCLC) With Exclusively Extracranial Disease Progression on Lorlatinib NCT06378892Phase 29 sites📍 Aviano📍 Florence📍 Lido di Camaiore Centro di Riferimento Oncologico - Aviano · Tests: Lorlatinib Intra-pemetrexed Plus Third-generation Small Molecule TKI Drugs (e.g. 'Osimertinib') Versus Third-generation Small Molecule TKI Drugs Alone for Leptomeningeal Metastasis From Epidermal Growth Factor Receptor Mutation-Positive Non-Small-cell Lung Cancer NCT06304441NA1 site📍 Huizhou Guangzhou Medical University · Tests: Osimertinib, Pemetrexed Sacituzumab Govitecan and Intrathecal Chemotherapy for Treating Leptomeningeal Metastases From Her2-negative Breast Cancer NCT06462092Phase 1, Phase 21 site📍 Huizhou Guangzhou Medical University · Tests: Sacituzumab Govitecan, Pemetrexed Assessment of I-PRF Versus Nano MTA Combined with I-PRF Scaffold in Vital Pulp Therapy in Mature Mandibular First Molars NCT06640205NA1 site📍 Cairo Future University in Egypt · Tests: pulpotomy Short Term Comparative Assessment of MTA and Biodentine in Complete Pulpotomy for Symptomatic Irreversible Pulpitis NCT07483788NA2 sites📍 Karachi📍 Karachi Dow University of Health Sciences · Tests: Biodentine pulpotomy A Clinical Study of Calderasib (MK-1084) and Other Treatments for Participants With Non-Small Cell Lung Cancer (MK-1084-007/KANDLELIT-007) NCT07190248Phase 3221 sites📍 Birmingham📍 Farmington📍 Stamford Merck Sharp & Dohme LLC · Tests: Calderasib, Pembrolizumab (+) Berahyaluronidase alfa, Pemetrexed, Cisplatin, Carboplatin Study of Izalontamab Brengitecan (BMS-986507) Versus Platinum-Pemetrexed for EGFR-mutated Non-small Cell Lung Cancer After Failure of EGFR TKI Therapy (IZABRIGHT-Lung01) NCT07100080Phase 2, Phase 3187 sites📍 Irvine📍 Orange📍 Edwards Bristol-Myers Squibb · Tests: Iza-bren, Carboplatin, Cisplatin, Pemetrexed A Study of the Safety and Efficacy of Pemetrexed Combined with Nivolumab Via Intraventricular Injection for the Treatment of Refractory Non-squamous Non-small Cell Lung Cancer with Leptomeningeal Metastases NCT06901817Phase 21 site📍 Shanghai Shanghai Cancer Hospital, China · Tests: Intraventricular Pemetrexed, Intraventricular Nivolumab, Intraventricular Dexamethasone To Evaluate and Compare the Effect of Orthograde and Retrograde MTA Root End Filling After Periapical Surgery in Posteriors NCT07808424NA1 site📍 Rohtak Postgraduate Institute of Dental Sciences Rohtak · Tests: Endodontic Micro-Surgery, Endodontic Micro-Surgery Clinical Trial of BMS-986504 in Recurrent GBM Patients NCT06883747EARLY Phase 11 site📍 Phoenix Nader Sanai · Tests: BMS-986504 Sequential Chemotherapy With Befotertinib in Non-Small Cell Lung Cancer (NSCLC) Patients With Resistance to Third-Generation EGFR-TKI NCT07181499Phase 22 sites📍 Guangzhou📍 Zhuhai Betta Pharmaceuticals Co., Ltd. · Tests: Befotertinib, Pemetrexed + Carboplatin Intrathecal PD-1/VEGF Bispecific Antibody Plus Pemetrexed for Leptomeningeal Metastasis NCT06809517Phase 1, Phase 21 site📍 Huizhou Guangzhou Medical University · Tests: AK112, Pemetrexed (Alimta) Intrathecal Pemetrexed for Leptomeningeal Metastasis in EGFR-Mutant NSCLC NCT05805631Phase 21 site📍 Taipei Taipei Veterans General Hospital, Taiwan · Tests: Pemetrexed Zanubrutinib With Pemetrexed to Treat Relapsed/Refractory Primary and Secondary Central Nervous System (CNS) Lymphomas NCT05681195Phase 21 site📍 Miami Baptist Health South Florida · Tests: Pemetrexed, Zanubrutinib, Autologous Stem Cell Transplant (ASCT), Whole Brain Radiation Therapy (WBRT) Clinical and Radiographic Success of MTA vs Biodentine NCT04863222Phase 41 site📍 Danville Geisinger Clinic · Tests: Biodentine, mineral trioxide aggregate (MTA) De-escalation Immunotherapy mAintenance Duration Trial for Stage IV Lung Cancer Patients With Disease Control After Chemo-immunotherapy Induction NCT05255302Phase 2, Phase 344 sites📍 Aix-en-Provence📍 Amiens📍 Angers Intergroupe Francophone de Cancerologie Thoracique · Tests: Pembrolizumab before randomization, Chemotherapy, Pemetrexed, Pembrolizumab after randomization Clinical and Radiographic Evaluation of Dia-Root Bio MTA for Indirect Pulp Capping in Young Permanent Molars NCT07894523NA1 site📍 Tanta Tanta University · Tests: Dia-Root Bio MTA Indirect Pulp Capping, MTA Plus Indirect Pulp Capping A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Locally Advanced or Metastatic Non-Squamous NSCLC NCT06627647Phase 3300 sites📍 Mobile📍 Chandler📍 Phoenix AstraZeneca · Tests: Rilvegostomig, Pembrolizumab, Carboplatin, Cisplatin, Pemetrexed A Study of AZD3470, a PRMT5 Inhibitor, Given as Monotherapy and in Combination in Patients With MTAP Deficient Advanced/Metastatic Solid Tumors NCT06130553Phase 1, Phase 221 sites📍 San Francisco📍 West Hollywood📍 New Haven AstraZeneca · Tests: AZD3470, Datopotamab deruxtecan
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