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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Malignant Glioma

Study in Children and Adolescents of 177Lu-DOTATATE (Lutathera®) Combined With the PARP Inhibitor Olaparib for the Treatment of Recurrent or Relapsed Solid Tumours Expressing Somatostatin Receptor (SSTR) (LuPARPed). NCT06607692Phase 1, Phase 21 site📍 Boadilla del Monte Fundación de investigación HM · Tests: Olaparib; 177Lu-DOTATATE A Trial of RSC-1255 for Treatment of Patients With Advanced Malignancies NCT04678648Phase 13 sites📍 Los Angeles📍 Denver📍 Nashville RasCal Therapeutics, Inc. · Tests: RSC-1255 Dose Escalation, RSC-1255 Dose Expansion Locoregional Administration of Genetically Engineered Cells (EGFR/IL13Rα2 Pool-CAR T Cells) for the Treatment of Recurrent or Progressive High-Grade Gliomas NCT07544992Phase 11 site📍 Duarte City of Hope Medical Center · Tests: Autologous Anti-EGFR/Anti-IL13Ralpha2 CAR T-cells, Biopsy Procedure, Biospecimen Collection, Echocardiography Test, FDG… Feasibility of Intra- and Post-operative Microdialysis During Neurosurgery for Central Nervous System Lesions NCT04047264NA1 site📍 Rochester Mayo Clinic · Tests: Microdialysis, Magnetic Resonance Imaging, Computed Tomography Intracranial Genetically Modified Immune Cells (TGFβR2KO/IL13Rα2 CAR T-Cells) for the Treatment of Recurrent or Progressive Glioblastoma or Grade 3 or 4 IDH-Mutant Astrocytoma NCT06815029Phase 11 site📍 Duarte City of Hope Medical Center · Tests: Biospecimen Collection, Chimeric Antigen Receptor T-Cell Therapy, Echocardiography, Fludeoxyglucose F-18, Intracranial … Repeated Super-selective Intraarterial Cerebral Infusion of Bevacizumab (Avastin) for Treatment of Relapsed GBM and AA NCT01269853Phase 1, Phase 21 site📍 New York Northwell Health · Tests: Bevacizumab, Bevacizumab Injection of Active Allogeneic Natural Killer Cells in Patients With Gliomas NCT06687681Phase 21 site📍 Tehran Marzieh Ebrahimi · Tests: NK cell therapy Evaluation of Clinical Efficacy and Safety of Specific Mode Electroacupuncture Stimulation for Paclitaxel Across BBB Delivery in Patients With Postoperative Recurrence of Malignant Glioma: A Single-arm Trial NCT06818331Phase 21 site📍 China The Third Affiliated hospital of Zhejiang Chinese Medical U… · Tests: SMES+PTX, Paclitaxel, Specific mode electroacupuncture stimulation Window Trial of Fluorescently Labeled Nivolumab-IRDye800 (Nivo800) in High Grade Glioma (HGG) NCT07210632EARLY Phase 11 site📍 Nashville Eben Rosenthal · Tests: Nivolumab, Nivolumab-IRDye800 Spectroscopic MRI Guided Proton Therapy in Assessing Metabolic Change in Pediatric Patients With Brain Tumors NCT04908709NA3 sites📍 Atlanta📍 Atlanta📍 Atlanta Emory University · Tests: Magnetic Resonance Spectroscopic Imaging, Proton Therapy Safety Study of the Repeated Opening of the Blood-brain Barrier With the SonoCloud® Device to Treat Malignant Brain Tumors in Pediatric Patients NCT05293197Phase 13 sites📍 Paris📍 Paris📍 Villejuif Assistance Publique - Hôpitaux de Paris · Tests: SonoCloud® (9 transducers) Retifanlimab With or Without Difluoromethylornithine for the Treatment of Progressive High Grade Gliomas NCT07468136Phase 1, Phase 21 site📍 Rochester Mayo Clinic · Tests: Biospecimen Collection, Eflornithine, Lumbar Puncture, Magnetic Resonance Imaging, Retifanlimab Atovaquone Combined With Radiation in Children With Malignant Brain Tumors NCT06624371Phase 12 sites📍 Atlanta📍 Atlanta Emory University · Tests: Atovaquone, Radiation Therapy Dabrafenib and/or Trametinib Rollover Study NCT03340506Phase 438 sites📍 Scottsdale📍 Bethesda📍 Columbus Novartis Pharmaceuticals · Tests: dabrafenib, trametinib Focused Ultrasound Blood-Brain Barrier Disruption for the Treatment of High-Grade Glioma in Patients Undergoing Standard Chemotherapy NCT07179328Phase 11 site📍 Toronto Sunnybrook Health Sciences Centre · Tests: Focused Ultrasound Next Generation Dome Helmet, Definity® Vial for (Perflutren Lipid Microsphere) Injectable Suspension ABY-029 Glioma Trial NCT07063693Phase 11 site📍 Lebanon Dartmouth-Hitchcock Medical Center · Tests: ABY-029 Fluorescence Enhanced Stereotactic Surgery (FESS) NCT07286903n/a1 site📍 Milan Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta The PALSUR-study: Palliative Care Versus Surgery in High-grade Glioma Patients (ENCRAM 2203) NCT06146738n/a8 sites📍 San Francisco📍 Boston📍 Leuven Jasper Gerritsen · Tests: Palliative Care, Tumor biopsy, Tumor resection Oxidative Phosphorylation Targeting In Malignant Glioma Using Metformin Plus Radiotherapy Temozolomide NCT04945148Phase 27 sites📍 Suresnes📍 Bron📍 Marseille Hopital Foch · Tests: Metformin, Radiation IMRT, Temozolomide Molecular Testing for the MD Anderson Cancer Center Personalized Cancer Therapy Program NCT01772771n/a1 site📍 Houston M.D. Anderson Cancer Center · Tests: Biospecimen Collection, Genetic Testing, Medical Chart Review Surgical Suction Aspirates Fluorescence Measurement NCT06736470n/a1 site📍 Kuopio Kuopio University Hospital ONC206 for Treatment of Newly Diagnosed, Recurrent Diffuse Midline Gliomas, and Other Recurrent Malignant CNS Tumors NCT04732065Phase 17 sites📍 San Francisco📍 Washington D.C.📍 Atlanta Sabine Mueller, MD, PhD · Tests: ONC206, Standard of Care Radiation Therapy, Optional Proton (1H) MR spectroscopy (MRS) NgFUS NIVO: NeuroNavigation-Guided Focused Ultrasound With Nivolumab in Relapsed and Progressive DMG and Other High Grade Brain Tumors NCT07664176Phase 11 site📍 Washington D.C. Children's National Research Institute · Tests: NeuroNavigation-Guided Focused Ultrasound (NgFUS), Lumason, Nivolumab Novel Indenoisoquinolone CMYC/TOPOISOMERASE 1 Inhibitor (LMP744) in Recurrent Glioblastoma NCT07416188Phase 1, Phase 21 site📍 Bethesda National Institute of Neurological Disorders and Stroke (NI… · Tests: LMP744, Conventional Surgery or Biopsy Intratumoral Extracellular Metabolic Impact of DFMO and AMXT 1501 in Patients With Diffuse or High Grade Glioma NCT05717153EARLY Phase 11 site📍 Rochester Mayo Clinic · Tests: Biospecimen Collection, Computed Tomography, Eflornithine, Magnetic Resonance Imaging, Polyamine Transport Inhibitor AM… MAPK Inhibition Combined With Anti-PD1 Therapy for BRAF-altered Pediatric Gliomas NCT06712875Phase 1, Phase 23 sites📍 Washington D.C.📍 Chicago📍 New York Ann & Robert H Lurie Children's Hospital of Chicago · Tests: Trametinib and Nivolumab, Dabrafenib, trametinib, nivolumab DB107-RRV, DB107-FC, and Radiation Therapy With or Without Temozolomide (TMZ) for High Grade Glioma NCT06504381Phase 1, Phase 25 sites📍 Los Angeles📍 San Diego📍 San Francisco University of California, San Francisco · Tests: DB107-RRV, DB107-FC, Radiation Therapy (RT), Temozolomide, Magnetic Resonance Imaging (MRI) Chronic CED of TPT for Recurrent Malignant Glioma NCT06666712Phase 11 site📍 New York Jeffrey N. Bruce · Tests: Topotecan Serial Advanced Magnetic Resonance Imaging Scan for Guidance of Personalized Adaptive Radiotherapy for High Grade Glioma NCT04771806n/a1 site📍 Houston M.D. Anderson Cancer Center · Tests: Magnetic Resonance Imaging, Neurocognitive Assessment, Quality-of-Life Assessment, Questionnaire Administration DETERMINE Trial Treatment Arm 06: Capmatinib in Adult Patients With Cancers Harbouring MET Dysregulations NCT06988475Phase 2, Phase 317 sites📍 Belfast📍 Birmingham📍 Bristol Cancer Research UK · Tests: Capmatinib
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