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Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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20 recruiting trials

for Malignant Solid Brain Tumors

Atamparib in Patients With Advanced Solid Tumors NCT07374419Phase 1, Phase 21 site๐Ÿ“ Shanghai Nerviano Medical Sciences (Shanghai) Ltd. ยท Tests: atamparib escalation levels, atamparib RP2D An Phase Ib/II Clinical Trial of TCC1727 Combination Therapy in Advanced Solid Tumors NCT07371663Phase 1, Phase 23 sites๐Ÿ“ Beijing๐Ÿ“ Zhengzhou๐Ÿ“ Hangzhou Beijing Tide Pharmaceutical Co., Ltd ยท Tests: TCC1727 tablet 90mg, TCC1727 tablet 120mg, TCC1727 tablet 160mg, benmelstobart Injection Cancer Genetic Testing in Ethnic Populations NCT04475640NA2 sites๐Ÿ“ Scottsdale๐Ÿ“ Jacksonville Mayo Clinic ยท Tests: Biospecimen Collection, Genetic Testing SRS Compared With FSRS for Treatment of Intact Metastatic Brain Disease, FRACTIONATE Trial NCT05222620Phase 27 sites๐Ÿ“ Scottsdale๐Ÿ“ Jacksonville๐Ÿ“ Albert Lea Mayo Clinic ยท Tests: Questionnaire Administration, Stereotactic Radiosurgery, Stereotactic Radiosurgery, Magnetic Resonance Imaging Arginine and Whole Brain Radiation Therapy for the Treatment of Patients With Brain Metastases NCT06328686EARLY Phase 11 site๐Ÿ“ Atlanta Emory University ยท Tests: Arginine, Biospecimen Collection, Computed Tomography, Magnetic Resonance Imaging, Spectroscopy Pre-Operative or Post-Operative Stereotactic Radiosurgery in Treating Patients With Operative Metastatic Brain Tumors NCT03750227Phase 34 sites๐Ÿ“ Scottsdale๐Ÿ“ Jacksonville๐Ÿ“ Bethesda Mayo Clinic ยท Tests: Conventional Surgery, Questionnaire Administration, Stereotactic Radiosurgery, Computed Tomography, Magnetic Resonance โ€ฆ Ex Vivo Drug Sensitivity Testing and Multi-Omics Profiling NCT05857969Phase 11 site๐Ÿ“ Miami Florida International University ยท Tests: Functional Precision Medicine DETERMINE Trial Treatment Arm 03: Entrectinib in Adult, Paediatric and Teenage/Young Adult Patients With ROS1 Gene Fusion-Positive Cancers. NCT05770544Phase 2, Phase 327 sites๐Ÿ“ Belfast๐Ÿ“ Birmingham๐Ÿ“ Birmingham Cancer Research UK ยท Tests: Entrectinib Safety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP Loss NCT06810544Phase 1, Phase 215 sites๐Ÿ“ Scottsdale๐Ÿ“ Irvine๐Ÿ“ Los Angeles Tango Therapeutics, Inc. ยท Tests: TNG456, abemaciclib Magnetic Resonance (MR) Imaging to Determine High Risk Areas in Patients With Malignant Gliomas and to Design Potential Radiation Plans and to Examine Metabolite Changes in Gliomas and Other Solid Tumors NCT00870129NA1 site๐Ÿ“ New York Memorial Sloan Kettering Cancer Center ยท Tests: MRI and advanced MRI sequences Educational Tools for the Improvement of Early Advance Care Planning in Adolescents and Young Adults With Advanced Solid Tumors and High-Grade Brain Tumors NCT07174661NA1 site๐Ÿ“ Scottsdale Mayo Clinic ยท Tests: Advance Care Planning, Educational Intervention, Electronic Health Record Review, Survey Administration Biobank and Register of Patients With Agresive Tumors for Translational and Analytical Research NCT05539677n/a1 site๐Ÿ“ Saint Petersburg N.N. Petrov National Medical Research Center of Oncology NK Cell Therapy for Malignant Solid Brain Tumors NCT07552233NA4 sites๐Ÿ“ Beijing๐Ÿ“ Qinhuangdao๐Ÿ“ Zhengzhou Peking University Third Hospital ยท Tests: Autologous NK cells Breathing Practice for Brain and Mental Health in Cancer and Neurodegenerative Diseases NCT06788886NA1 site๐Ÿ“ Rochester Mayo Clinic ยท Tests: Biospecimen Collection, Exercise Intervention, Magnetic Resonance Imaging, Questionnaire Administration, Respiratory Thโ€ฆ Study of 203Pb-RMX-VH-PIB Dosimetry and Biodistribution in Patients With Glioblastoma Multiform (GBM) and Pancreatic Ductal Adenocarcinoma (PDAC) NCT07733674Phase 11 site๐Ÿ“ Houston Radiomedix, Inc. ยท Tests: 203Pb-RMX-VHPIB injection, SPECT/CT Imaging Neurocognition in Patients With Multiple Brain Metastases Treated With Radiosurgery NCT03184038NA2 sites๐Ÿ“ Sewell๐Ÿ“ Philadelphia Sidney Kimmel Comprehensive Cancer Center at Thomas Jeffersโ€ฆ ยท Tests: Cognitive Assessment, Stereotactic Radiosurgery, Stereotactic Body Radiation Therapy, Quality-of-Life Assessment NBM-BMX Administered Orally to Patients With Solid Tumors or Newly Diagnosed Glioblastoma NCT06012695Phase 1, Phase 24 sites๐Ÿ“ Kaohsiung City๐Ÿ“ Taichung๐Ÿ“ Taipei Novelwise Pharmaceutical Corporation ยท Tests: NBM-BMX Capsule, Temozolomide, Standard radiotherapy CBL0137 for the Treatment of Relapsed or Refractory Solid Tumors, Including CNS Tumors and Lymphoma NCT04870944Phase 1, Phase 235 sites๐Ÿ“ Birmingham๐Ÿ“ Phoenix๐Ÿ“ Los Angeles Children's Oncology Group ยท Tests: Biospecimen Collection, Bone Marrow Aspirate, Bone Marrow Biopsy, Echocardiography Test, FACT Complex-targeting Curaxinโ€ฆ Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis NCT06047379Phase 1, Phase 28 sites๐Ÿ“ Beverly Hills๐Ÿ“ Glendale๐Ÿ“ Los Angeles Neonc Technologies, Inc. ยท Tests: NEO212 Oral Capsule, Ipilimumab, Pembrolizumab, Nivolumab, Regorafenib Intravital Microscopy in Human Solid Tumors NCT03823144NA1 site๐Ÿ“ Jacksonville Mayo Clinic ยท Tests: Diagnostic Microscopy, Fluorescein Sodium Injection
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