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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Melanoma Stage IV

Immunotherapy Efficacy and PD-L1 as a Predictive Biomarker in Metastatic Melanoma in Slovenia NCT07422779NA1 site📍 Ljubljana Institute of Oncology Ljubljana · Tests: Pembrolizumab, Nivolumab, Ipilimumab A Phase I/II Trial of Vemurafenib and Metformin to Melanoma Patients NCT01638676Phase 1, Phase 21 site📍 Louisville University of Louisville · Tests: Vemurafenib, Metformin Long-Term Follow-up of Patients Treated With Miltenyi Cell and Gene Therapies NCT06508775NA7 sites📍 Berlin📍 Cologne📍 Erlangen Miltenyi Biomedicine GmbH · Tests: MB-CART19.1, MB-CART20.1, MB-CART2019.1 Dual-Target CSPG4/GD2 CAR-NK Cells for Advanced Melanoma NCT07627698Phase 1, Phase 21 site📍 Shenzhen Beijing Biotech · Tests: EB-DTKN-401 allogeneic dual-target CSPG4/GD2 CAR-NK cells, Fludarabine, Cyclophosphamide Safety and Efficacy of OBX-115 in Advanced Solid Tumors NCT06060613Phase 1, Phase 210 sites📍 Los Angeles📍 Los Angeles📍 Stanford Obsidian Therapeutics, Inc. · Tests: OBX-115 Detection of the BRAF V600E Mutation in Liquid Biopsy Using the CRISPR/Cas12a System NCT07870265NA1 site📍 Brno Masaryk Memorial Cancer Institute · Tests: Novel CRISPR/Cas12a Electrochemical Bioassay, Reference Standard Molecular Diagnostics (NGS and ddPCR), Serial Peripher… Evaluation of the Safety, Efficacy, and Pharmacokinetics of NBM-BMX in Patients With Metastatic Uveal Melanoma NCT07136181Phase 1, Phase 23 sites📍 Scottsdale📍 Denver📍 Nashville Novelwise Pharmaceutical Corporation · Tests: NBM-BMX Capsule are proprietary products developed by Novelwise Pharmaceutical Corporation (Novelwise) for treatment of… To Evaluate the Safety and Efficacy of ADP-TILIL7 in Patients With Locally Advanced or Metastatic Melanoma NCT06204991Phase 12 sites📍 Herlev📍 Herlev Inge Marie Svane · Tests: ADP-TILIL7, Cyclophosphamide, Fludarabine Phosphate, Proleukin Morning Versus Afternoon Administration of Immunotherapy for the Treatment of Advanced or Metastatic Solid Tumors, The Knight SHIFT Study NCT07405086Phase 41 site📍 Portland OHSU Knight Cancer Institute · Tests: Biospecimen Collection, Immune Checkpoint Inhibitor Anti PD-1 Plus Postbiotic Versus Anti PD-1 Alone in Locally Advanced or Metastatic, Treatment naïve, Cutaneous Melanoma Study NCT07050940NA5 sites📍 Bari📍 Torino📍 Bari Azienda Ospedaliera di Perugia · Tests: Postbiotic, AntiPD1 Avapritinib for the Treatment of CKIT or PDGFRA Mutation-Positive Locally Advanced or Metastatic Malignant Solid Tumors NCT04771520Phase 21 site📍 Houston M.D. Anderson Cancer Center · Tests: Avapritinib A Study of LN-144 or LN-145 in People With Advanced Uveal Melanoma, Undifferentiated Pleomorphic Sarcoma, Dedifferentiated Liposarcoma, or Angiosarcoma NCT05607095Phase 12 sites📍 Harrison📍 New York Memorial Sloan Kettering Cancer Center · Tests: Lifileucel (LN-144/LN-145) Beta Glucan's Effect on Pembrolizumab Immunologic Response in Stage III-IV Melanoma NCT04513028NA1 site📍 Louisville Kelly McMasters · Tests: Beta-Glucan Dabrafenib and/or Trametinib Rollover Study NCT03340506Phase 438 sites📍 Scottsdale📍 Bethesda📍 Columbus Novartis Pharmaceuticals · Tests: dabrafenib, trametinib IACS-6274 With or Without Bevacizumab and Paclitaxel for the Treatment of Advanced Solid Tumors NCT05039801Phase 11 site📍 Houston M.D. Anderson Cancer Center · Tests: Bevacizumab, Glutaminase-1 Inhibitor IACS-6274, Paclitaxel, Capivasertib Anti-NY-ESO-1 TCR-Gene Engineered Lymphocytes Given by Infusion to Patients With NY-ESO-1 -Expressing Metastatic Cancers NCT05296564Phase 1, Phase 21 site📍 Jerusalem Hadassah Medical Organization · Tests: CYCLOPHOSPHAMIDE and FLUDARABIN, Cyclophosphamide, HBI 0201-ESO TCRT, Aldesleukin Immune Response to Percutaneous Hepatic Perfusion With Melphalan for Ocular Melanoma Metastatic to the Liver NCT07364474NA1 site📍 Boston Massachusetts General Hospital · Tests: Melphalan through Percutaneous Hepatic Perfusion, Melphalan through Percutaneous Hepatic Perfusion in combination with … Study to Investigate Lifileucel Regimen Plus Pembrolizumab Compared With Pembrolizumab Alone in Participants With Untreated Advanced Melanoma. NCT05727904Phase 382 sites📍 Birmingham📍 Duarte📍 Los Angeles Iovance Biotherapeutics, Inc. · Tests: Lifileucel plus Pembrolizumab, Pembrolizumab with Optional Crossover Period Follow-up of a National Cohort of Melanoma Resectable Stage II, Stage III or IV Patients or Unresectable Primary NCT02828202n/a27 sites📍 Amiens📍 Annecy📍 Besançon Assistance Publique - Hôpitaux de Paris · Tests: Biological, Tissular, Quality of life Nilotinib Plus Dabrafenib/Trametinib or Encorafenib/Binimetinib in Metastatic Melanoma NCT04903119Phase 14 sites📍 Iowa City📍 Lexington📍 Easton Rina Plattner · Tests: Nilotinib 100mg, Nilotinib 200mg, Nilotinib 300mg, Nilotinib 400mg, Dabrafenib Crizanlizumab Alone or in Combination With Nivolumab for Glioblastoma and Melanoma With Brain Metastases NCT05909618Phase 21 site📍 Ramat Gan Sheba Medical Center · Tests: Crizanlizumab-Tmca 10 MG/1 ML Intravenous Solution [ADAKVEO], Nivolumab 10 MG/1 ML Intravenous Solution [OPDIVO] Study to Compare Pharmacokinetics, Efficacy, Safety, and Immunogenicity of MB11 Versus EU-/US-Opdivo® in Subjects With Previously Untreated Advanced [Unresectable or Metastatic] Melanoma NCT07221734Phase 319 sites📍 Funchal📍 Chernivtsi📍 Ivano-Frankivsk mAbxience Research S.L. · Tests: MB11 (Proposed Nivolumab Biosimilar), EU-Opdivo®, US- sourced Opdivo® Symptoms of Immune Checkpoint Inhibitor Therapy in Cutaneous Melanoma NCT07148245n/a1 site📍 San Francisco University of California, San Francisco · Tests: Blood Sample, Health Related Quality of Life Questionnaires (HRQoL), Medical Chart Review Neoadjuvant and Adjuvant Anti-PD1 or Combinations for Locoregionally Advanced Melanoma NCT06295159Phase 21 site📍 Tampa H. Lee Moffitt Cancer Center and Research Institute · Tests: Nivolumab, Nivolumab + Relatlimab, Ipilimumab Precision Radiation of Immune Checkpoint Therapy Resistant Melanoma Metastases NCT04793737NA1 site📍 Stockholm Karolinska University Hospital · Tests: Precision Radiation (SBRT) Neoadjuvant SHR-1210 Plus Apatinib for Resectable Stage III-IV Acral Melanoma NCT04331093Phase 21 site📍 Changchun Di Wu · Tests: SHR-1210+Apatinib FMT to Convert Response to Immunotherapy NCT05251389Phase 1, Phase 21 site📍 Amsterdam The Netherlands Cancer Institute · Tests: Fecal microbiota transplantation Tebentafusp and Roginolisib in Uveal Melanoma to Prolong T-cell Homeostasis NCT07203391Phase 12 sites📍 Sydney📍 Melbourne St Vincent's Hospital, Sydney · Tests: roginolisib Intralesional Influenza Vaccine for the Treatment of Stage I-IV Melanoma NCT04697576Phase 11 site📍 Columbus Carlo Contreras · Tests: Ipilimumab, Nivolumab, Pembrolizumab, Quadrivalent Inactivated Influenza Vaccine, Resection Cryoablation Combined With Hepatic Arterial Infusion of Iparomlimab and Tuvonralimab (QL1706), Intravenous Dacarbazine, and Oral Lenvatinib in Patients With Liver Metastases From Malignant Melanoma: a Single-arm, Phase II, Prospective Trial NCT07847359Phase 21 site📍 Guangzhou Sun Yat-sen University · Tests: Cryoablation, Iparomlimab and Tuvonralimab, Dacarbazine, Lenvatinib
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