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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Metastatic Oral Cavity Carcinoma

Oral Hedgehog Inhibitors in the Treatment of Basal Cell Carcinoma in the Netherlands: a Prospective Registration Study NCT05463757n/a8 sites๐Ÿ“ Nijmegen๐Ÿ“ Maastricht๐Ÿ“ Amsterdam Maastricht University Medical Center ยท Tests: Vismodegib, Sonidegib TMV Vaccine Therapy Alone and With Pembrolizumab for the Treatment of Recurrent and/or Metastatic Head and Neck Squamous Cell Cancer NCT06868433Phase 12 sites๐Ÿ“ Atlanta๐Ÿ“ Atlanta Emory University ยท Tests: Autologous Tumor Membrane Vesicles Vaccine, Biospecimen Collection, Computed Tomography, Echocardiography, Magnetic Resโ€ฆ Study Comparing Different Neck Treatment Approaches in Patients With Oral Cancer Without Visible Neck Spread NCT07726199NA1 site๐Ÿ“ Kolhฤpur Kolhapur Cancer Centre - Cancer Centers of America ยท Tests: Selective Neck Dissection (Levels I-IV), Intervention : Selective Neck Dissection (Levels I-III) Docetaxel and SX-682 in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma, Salivary Gland Carcinoma, and Advanced Prostate Cancer NCT07667400Phase 1, Phase 21 site๐Ÿ“ Bethesda National Cancer Institute (NCI) ยท Tests: SX-682, DTX Methotrexate, Erlotinib, and Celecoxib for the Treatment of Recurrent/Metastatic Head and Neck Cancer in a Rural Midwest United States Population NCT06997068Phase 21 site๐Ÿ“ Rochester Mayo Clinic ยท Tests: Celecoxib, Erlotinib Hydrochloride, Imaging Procedure, Interview, Methotrexate Tissue Sample Collection From Patients With Head and Neck Cancer and From Healthy Participants NCT00898638n/a4 sites๐Ÿ“ Nashville๐Ÿ“ Nashville๐Ÿ“ Nashville Vanderbilt University Medical Center ยท Tests: biologic sample preservation procedure, medical chart review Assessing an Oral EGFR Inhibitor, DZD9008 in Patients With Advanced Non-small Cell Lung Cancer(NSCLC) With EGFR Mutations (WU-KONG15) NCT05559645NA1 site๐Ÿ“ Beijing Peking Union Medical College Hospital ยท Tests: DZD9008, DZD9008 Biomarkers in Patients With Respiratory Tract Dysplasia or Lung Cancer, Head and Neck Cancer, or Aerodigestive Tract Cancer and in Normal Volunteers NCT00900419n/a1 site๐Ÿ“ Aurora University of Colorado, Denver ยท Tests: immunohistochemistry staining method, laboratory biomarker analysis, sputum cytology, biopsy Association Between Health Care Provider (HCP)-Assessed ECOG Performance Status (PS) and Overall Survival, and Objectively Measure of Physical Activity (PA) Levels in Advance-cancer Patients" NCT01365169NA1 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Exercise Intervention, Health Telemonitoring, Health Telemonitoring, Health Telemonitoring, Health Telemonitoring A Study Evaluating Ficerafusp Alfa (BCA101) QW in Combination With Pembrolizumab vs Alternative Ficerafusp Alfa Dosing in 1L R or M HNSCC NCT07807163Phase 27 sites๐Ÿ“ Fort Myers๐Ÿ“ Orlando๐Ÿ“ St. Petersburg Bicara Therapeutics ยท Tests: Ficerafusp alfa, Pembrolizumab (KEYTRUDAยฎ) Integrated Cancer Repository for Cancer Research NCT02012699n/a42 sites๐Ÿ“ Greenwood Village๐Ÿ“ Manchester๐Ÿ“ Daytona Beach University of Nebraska Study to Evaluate the Safety and Efficacy of Oral NRC-2694-A in Combination With Paclitaxel in Patients With Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma, Who Progressed on or After Immune Checkpoint Inhibitor Therapy NCT05283226Phase 213 sites๐Ÿ“ Fullerton๐Ÿ“ Los Angeles๐Ÿ“ Boca Raton NATCO Pharma Ltd. ยท Tests: NRC-2694-A, Paclitaxel CB-103 With Either Lenvatinib or Abemaciclib in Patients With NOTCH ACC NCT05774899Phase 1, Phase 21 site๐Ÿ“ Boston Michael J. Dennis, MD ยท Tests: CB-103, Abemaciclib, Lenvatinib Afatinib in Patients With Fanconi Anemia (FA) and Advanced Head and Neck Squamous Cell Carcinoma (HNSCC) NCT06648096Phase 1, Phase 22 sites๐Ÿ“ Hanover๐Ÿ“ Barcelona Fundaciรณ Institut de Recerca de l'Hospital de la Santa Creuโ€ฆ ยท Tests: Afatinib Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytrudaยฎ) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist) NCT04198766Phase 1, Phase 242 sites๐Ÿ“ Duarte๐Ÿ“ Glendale๐Ÿ“ Los Angeles Inhibrx Biosciences, Inc ยท Tests: INBRX-106 - Hexavalent OX40 agonist antibody, pembrolizumab 200 mg, pembrolizumab 400 mg, Carboplatin AUC-5, Carboplatiโ€ฆ Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies NCT05786924Phase 1, Phase 249 sites๐Ÿ“ Gilbert๐Ÿ“ Los Angeles๐Ÿ“ Los Angeles Institut de Recherches Internationales Servier ยท Tests: S241656, FOLFOX6/FOLFOX7, FOLFIRI, Cetuximab, Panitumumab First in Human Multicenter Open Name Dose-increase, Consolidation Method to Study Safety Drug-level in Blood & Drug Metabolism Clinical Activity of Oral JBI-778 in Lung Cancer Patients With, Without Brain Metastasis IDH Mutated WHO Grade 3,4 Recurrent Glioma, Salivary Glands Tumor NCT07755397Phase 16 sites๐Ÿ“ Surat๐Ÿ“ Bangalore๐Ÿ“ Mumbai Jubilant Therapeutics India Limited ยท Tests: JBI-778 A Study of Oral 7HP349 (Alintegimod) in Combination With Ipilimumab Followed by Nivolumab Monotherapy NCT06362369Phase 1, Phase 25 sites๐Ÿ“ Aurora๐Ÿ“ Lake Mary๐Ÿ“ Lebanon 7 Hills Pharma, LLC ยท Tests: Alintegimod, Ipilimumab, Nivolumab Remote Audiometry to Monitor for Treatment-Related Hearing Loss in Patients With H&N SCC Receiving Cisplatin and/or Radiation NCT06662058NA1 site๐Ÿ“ Atlanta Emory University ยท Tests: Audiometric Test, Audiometric Test, Audiometric Test, Interview Alpha Radiation Emitters Device (DaRT) for the Treatment of Cutaneous, Mucosal or Superficial Soft Tissue Neoplasia. NCT03889899NA1 site๐Ÿ“ Haifa Alpha Tau Medical LTD. ยท Tests: Radiation: Diffusing Alpha Radiation Emitters Therapy (DaRT) Circulating Tumor Cell Counts in Postoperative ENE-Positive Oral Cavity Cancer Patients After Adjuvant CCRT NCT07296250NA1 site๐Ÿ“ Taoyuan City Chang Gung Memorial Hospital ยท Tests: low-dose oral chemotherapy Study Comparing Limited and Extensive Neck Surgery in Oral Cancer Patients With Neck Spread NCT07717307NA1 site๐Ÿ“ Kolhฤpur Kolhapur Cancer Centre - Cancer Centers of America ยท Tests: Selective Neck Dissection (Levels I-IV), Modified Neck Dissection (Levels I-V) Sapanisertib and Serabelisib (PIKTOR) in Various Combinations in Patients With HR+/HER2- Advanced/Metastatic Breast Cancer NCT07558733Phase 1, Phase 27 sites๐Ÿ“ Los Angeles๐Ÿ“ Lone Tree๐Ÿ“ Springfield Faeth Therapeutics ยท Tests: Serabelisib, Sapanisertib, Fulvestrant Lovastatin and Pembrolizumab for the Treatment of Patients With Recurrent or Metastatic Head and Neck Cancer, LAPP Trial NCT06636734Phase 22 sites๐Ÿ“ Atlanta๐Ÿ“ Atlanta Emory University ยท Tests: Biospecimen Collection, Computed Tomography, Lovastatin, Magnetic Resonance Imaging, Pembrolizumab Testing the Addition of Anti-Cancer Drug, Cetuximab, to Standard of Care Treatment (Pembrolizumab) for Returning or Spreading Head and Neck Cancer After Previous Treatment NCT06589804Phase 3202 sites๐Ÿ“ Little Rock๐Ÿ“ Marysville๐Ÿ“ Palo Alto National Cancer Institute (NCI) ยท Tests: Biospecimen Collection, Cetuximab, Computed Tomography, Magnetic Resonance Imaging, Pembrolizumab 5-Fluorouracil Response and Optimization STudy (The FROST Trial) NCT07419464Phase 21 site๐Ÿ“ St Louis Washington University School of Medicine ยท Tests: 5-Fluorouracil Neck Observation or Elective Neck Dissection in cT1N0M0 OSCC NCT06623266NA1 site๐Ÿ“ Shanghai Huashan Hospital ยท Tests: Neck management BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study NCT05136196Phase 2232 sites๐Ÿ“ Phoenix๐Ÿ“ Little Rock๐Ÿ“ Beverly Hills National Cancer Institute (NCI) ยท Tests: Biopsy Procedure, Biospecimen Collection, Cabozantinib S-malate, Computed Tomography, Magnetic Resonance Imaging A Study of Sacituzumab Govitecan in Combination With Cetuximab in People With Head and Neck Squamous Cell Cancer (HNSCC) NCT07063212Phase 27 sites๐Ÿ“ Basking Ridge๐Ÿ“ Middletown๐Ÿ“ Montvale Memorial Sloan Kettering Cancer Center ยท Tests: Sacituzumab Govitecan, Cetuximab VMD-928 Monotherapy and in Combination With Pembrolizumab to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma NCT03556228Phase 1, Phase 215 sites๐Ÿ“ Santa Rosa๐Ÿ“ Hartford๐Ÿ“ Washington D.C. VM Oncology, LLC ยท Tests: VMD-928 100 mg Tablet, VMD-928 Tablet and Pembrolizumab (200 mg)
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