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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Microsatellite Stable Metastatic Colorectal Cancer

Standard Systemic Therapy Combined With High/Low-dose Radiotherapy Plus Toripalimab for Metastatic Colorectal Cancer NCT06525428Phase 21 site๐Ÿ“ Shanghai Fudan University ยท Tests: standard systemic therapy combined with high/low-dose radiotherapy plus toripalimab A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer NCT07284849Phase 3293 sites๐Ÿ“ Mobile๐Ÿ“ Tucson๐Ÿ“ Tucson Incyte Corporation ยท Tests: INCA33890, Placebo, Bevacizumab, FOLFOX Personalized Ultrafractionated Stereotactic Adaptive Radiotherapy (PULSAR ) Combined With Anti-PD1๏ผŒChemotherapy and Target Therapy for Metastatic Colorectal Cancer NCT06841159Phase 21 site๐Ÿ“ Shanghai Fudan University ยท Tests: Ultra-fractionated radiation therapy, Sintilimab, Standard systemic therapy A Phase II Study of Sintilimab Combined With Ipilimumab N01, Cetuximab and Dabrafenib in Patients With Microsatellite-Stable, BRAF V600E-Mutated Metastatic Colorectal Cancer NCT07506109Phase 24 sites๐Ÿ“ Beijing๐Ÿ“ Wuhan๐Ÿ“ Chengdu Tianjin Medical University Cancer Institute and Hospital ยท Tests: Ipilimumab N01, Sintilimab, Cetuximab, Dabrafenib Efficacy and Safety of Chemotherapy With XELOX (Oxaliplatin + Capecitabine) and Bevacizumab in Combination With Adebrelimab in First-line Treatment of Microsatellite Stable (MSS) Initially Unresectable Metastatic Colorectal Cancer NCT06282445Phase 21 site๐Ÿ“ Jinhua The Fourth Affiliated Hospital of Zhejiang University Schooโ€ฆ ยท Tests: Adebrelimab, Oxaliplatin, Capecitabine, Bevacizumab Testing the Effectiveness of the Anti-cancer Drug Pidnarulex (CX-5461), in Combination With Another Anti-cancer Drug Cemiplimab (REGN2810), in Treating Refractory Microsatellite Stable Colorectal Cancer NCT07147231Phase 1, Phase 27 sites๐Ÿ“ Aurora๐Ÿ“ Washington D.C.๐Ÿ“ Atlanta National Cancer Institute (NCI) ยท Tests: Biopsy Procedure, Biospecimen Collection, Cemiplimab, Computed Tomography, Magnetic Resonance Imaging Cetuximab and Envafolimab Plus mFOLFOXIRI as First-line Treatment for RAS/BRAF Wild-type, MSS, Unresectable Left-side Metastatic Colorectal Cancer NCT05959356Phase 23 sites๐Ÿ“ Foshan๐Ÿ“ Guangzhou๐Ÿ“ Guiyang Sun Yat-sen University ยท Tests: Cetuximab + Envafolimab + mFOLFOXIRI, Cetuximab + mFOLFOX6 Vitamin E Combined With Fruquintinib and Tislelizumab in Microsatellite Stabilized Metastatic Colorectal Cancer Patients NCT05771181Phase 21 site๐Ÿ“ Shanghai Fudan University ยท Tests: Vitamin E, Fruquintinib, Tislelizumab FOLFIRI and Bevacizumab With or Without Pelareorep for Second-Line Treatment of Metastatic RAS-Mutated, Microsatellite-Stable Colorectal Cancer NCT07446322Phase 219 sites๐Ÿ“ Homewood๐Ÿ“ Beverly Hills๐Ÿ“ Encino Oncolytics Biotech ยท Tests: Bevacizumab, FOLFIRI, Pelareorep Isunakinra Alone and in Combination With Pembrolizumab in Patients With Colorectal Cancer (MSS) NCT06634875Phase 23 sites๐Ÿ“ Los Angeles๐Ÿ“ Newport Beach๐Ÿ“ Atlanta Buzzard Pharmaceuticals ยท Tests: isunakinra Cadonilimab in Combination With Bevacizumab and FOLFOX Regimen for the First-Line Treatment of Advanced Unresectable MSS-Type, RAS-Mutated Metastatic Colorectal Cancer NCT06218810Phase 21 site๐Ÿ“ Shanghai Fudan University ยท Tests: Cadonilimab + bevacizumab + FOLFOX Neoadjuvant Dupilumab and Toripalimab in MSS CRC Subjects With Resectable Liver Metastases NCT07277322Phase 1, Phase 21 site๐Ÿ“ New York Dan Feng ยท Tests: Dupilumab, Toripalimab KN 046 Plus Regorafenib in MSS Metastatic Colorectal Cancer NCT05985109Phase 21 site๐Ÿ“ Beijing Peking University Cancer Hospital & Institute ยท Tests: KN046, regorafenib COLONYVAQโ„ข, a Quantum-Classical Guided Personalized Neoantigen Vaccine for MSS Stage III Colorectal Cancer NCT07328087EARLY Phase 11 site๐Ÿ“ Thessaloniki Biogenea Pharmaceuticals Ltd. ยท Tests: Experimental: COLONYVAQ-CRC + mFOLFOX6 or CAPOX + Nivolumab Efficacy and Safety of Combined With Immunotherapy After Induction Therapy With Chemotherapy and Targeted Therapy in the First-line Treatment of Microsatellite Stable (MSS) Initially Unresectable Metastatic Colorectal Cancer NCT06176885Phase 21 site๐Ÿ“ Jinhua yue junhan ยท Tests: Camrelizumab FOG-001 in Locally Advanced or Metastatic Solid Tumors NCT05919264Phase 1, Phase 233 sites๐Ÿ“ Phoenix๐Ÿ“ Scottsdale๐Ÿ“ Tucson Parabilis Medicines, Inc. ยท Tests: FOG-001, mFOLFOX-6, Nivolumab, Trifluridine/tipiracil, Bevacizumab A Study of ASP1002 in Adults for Treatment of Solid Tumors NCT05719558Phase 115 sites๐Ÿ“ New Haven๐Ÿ“ Plainville๐Ÿ“ Gainesville Astellas Pharma Global Development, Inc. ยท Tests: ASP1002, Bevacizumab, Oxaliplatin, Leucovorin, Fluorouracil 5FU/LV, Irinotecan, Temozolomide and Bevacizumab for MGMT Silenced, Microsatellite Stable Metastatic Colorectal Cancer. NCT04689347Phase 1, Phase 23 sites๐Ÿ“ Milan๐Ÿ“ Padova๐Ÿ“ Pisa Fondazione IRCCS Istituto Nazionale dei Tumori, Milano ยท Tests: Bevacizumab, Irinotecan, Leucovorin, 5Fluorouracil, Temozolomide LB-100 (PP2A Inhibitor) and Atezolizumab (PD-L1 Inhibitor) in Metastatic Colorectal Cancer Patients NCT06012734Phase 11 site๐Ÿ“ Amsterdam The Netherlands Cancer Institute ยท Tests: LB-100, Atezolizumab A Study of NX-1607 in Adults With Advanced Malignancies NCT05107674Phase 117 sites๐Ÿ“ Duarte๐Ÿ“ Los Angeles๐Ÿ“ San Francisco Nurix Therapeutics, Inc. ยท Tests: NX-1607, Paclitaxel Testing the Addition of an Anti-Cancer Drug, Abemaciclib, to the Usual Chemotherapy Treatment (5-Fluorouracil) for Metastatic, Refractory Colorectal Cancer NCT06654037Phase 18 sites๐Ÿ“ Irvine๐Ÿ“ Orange๐Ÿ“ The Bronx National Cancer Institute (NCI) ยท Tests: Abemaciclib, Biopsy Procedure, Biospecimen Collection, Fluorouracil, Radiologic Imaging Procedure A Clinical Study to Test if an Investigational Treatment Called BNT314 When Used in Combination With Another Investigational Treatment Pumitamig (BNT327) and Chemotherapy, is Beneficial and Safe for Patients With Advanced Colorectal Cancer NCT07079631Phase 1, Phase 214 sites๐Ÿ“ New Haven๐Ÿ“ Grand Rapids๐Ÿ“ Cleveland BioNTech SE ยท Tests: BNT314, Pumitamig, SoC chemotherapy treatment 1, SoC chemotherapy treatment 2, Bevacizumab Comparing Chidamide+Sintilimab+Bev With Standard Second-line FOLFIRI+Bev in Advanced MSS/pMMR mCRC NCT05768503Phase 312 sites๐Ÿ“ Hefei๐Ÿ“ Foshan๐Ÿ“ Guangzhou Sun Yat-sen University ยท Tests: Experimental drug, Control Rx A Study to Investigate the Safety, Pharmacokinetics, and Preliminary Efficacy of IDE574 Therapy in Adult Participants With Advanced Solid Tumors NCT07540572Phase 111 sites๐Ÿ“ Plantation๐Ÿ“ East Brunswick๐Ÿ“ Lake Success IDEAYA Biosciences ยท Tests: IDE574, Fulvestrant injection - IKF/AIO-QUINTIS - Evaluating Fruquintinib in Combination With Tislelizumab in Microsatellite Stable / Proficient Mismatch Repair (MSS/pMMR) Metastatic Colorectal Cancer Without Active Liver Metastases NCT06856837Phase 223 sites๐Ÿ“ Linz๐Ÿ“ Salzburg๐Ÿ“ Wiener Neustadt Institut fรผr Klinische Krebsforschung IKF GmbH at Krankenhaโ€ฆ ยท Tests: Fruquintinib, Tislelizumab, Trifluridine/tipiracil, Bevacizumab Sequential Immunochemotherapy Treatment with Pembrolizumab Plus Dendritic Cell (DC) Vaccine Followed by Trifluridine/Tipiracil Plus Bevacizumab in Refractory Mismatch-repair-proficient (pMMR) or Microsatellite-stable (MSS) Metastatic Colorectal Cancer NCT06522919Phase 22 sites๐Ÿ“ Meldola๐Ÿ“ Tricase Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRโ€ฆ ยท Tests: Autologous Dendritic Cell (DC) Vaccine Combination Immunotherapy for the Treatment of Chemotherapy-refractory Metastatic MSS CRC NCT07281716Phase 1, Phase 21 site๐Ÿ“ New York Dan Feng ยท Tests: Nadunolimab, Toripalimab Phase 1 Study Of SAR445877 In Combination With FOLFOX6 And Bevacizumab As First-Line Treatment For Microsatellite Stable Metastatic Colorectal Cancer NCT07500298Phase 11 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: SAR445877, FOLFOX6, Bevacizumab Phase 2 Study of SR-8541A in Combination With Botensilimab and Balstilimab in Subjects With Refractory Metastatic Microsatellite Stable Colorectal Cancer (MSS-CRC) NCT06589440Phase 26 sites๐Ÿ“ Morristown๐Ÿ“ Austin๐Ÿ“ Dallas Stingray Therapeutics ยท Tests: SR-8541A Testing the Combination of the Anti-Cancer Drugs Temozolomide and M1774 to Evaluate Their Safety and Effectiveness NCT05691491Phase 1, Phase 223 sites๐Ÿ“ Irvine๐Ÿ“ La Jolla๐Ÿ“ Orange National Cancer Institute (NCI) ยท Tests: Biopsy Procedure, Biospecimen Collection, Computed Tomography, Magnetic Resonance Imaging, Temozolomide
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