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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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15 recruiting trials

for Middle and Low Rectal Cancer

Neoadjuvant Chemoradiotherapy Plus Tislelizumab With or Without Probio-M9 in pMMR/MSS Locally Advanced Rectal Cancer NCT07458529Phase 21 site📍 Beijing Seventh Medical Center of PLA General Hospital · Tests: CRT+PD-1 inhibitor+Probio-M9, CRT+PD-1 inhibitor+placebo Nodes-sparing Short-course Radiation Combined With CAPOX and Tislelizumab for MSS Middle and Low Rectal Cancer NCT05972655Phase 21 site📍 Hanzhou Sir Run Run Shaw Hospital · Tests: Modified short-course radiotherapy, PD-1 antibody, Capecitabine, Oxaliplatin Standard Dose Versus High Dose of Radiotherapy in Rectal Preservation With Chemo-radiotherapy in Rectal Cancer Patients NCT04095299Phase 35 sites📍 Aalborg📍 Copenhagen📍 Næstved Vejle Hospital · Tests: 50.4 Gy to the tumor and elective volume, 62 Gy to the clinical tumor volume and 50.4 Gy to the elective volume, Capeci… Safety of Mid and Low Rectal Cancer Surgery Without Dissection of the No.253 Lymph Node (S-M-O-O-T-H) NCT06146946NA8 sites📍 Beijing📍 Beijing📍 Beijing Cancer Institute and Hospital, Chinese Academy of Medical S… · Tests: Dissection of the No.253 lymph node, Omitting the dissection of the No.253 lymph node REsults of LOw Anterior Resections With or Without Preventive Stoma in Nonemergency Department NCT07463261NA7 sites📍 Moscow📍 Moscow📍 Moscow ANO Scientific and Practical Club for the Development of Mo… · Tests: Without a preventive stoma, With a preventive stoma Somatostatin Plus Clear Liquid Diet Versus Diverting Stoma in Patients With Rectal Cancer Undergoing Ultra-Low Anterior Resection NCT07605611NA3 sites📍 Ezhou📍 Wuhan📍 Wuhan Tongji Hospital · Tests: Somatostatin, Clear Liquid Diet, Prophylactic Diverting Stoma Neoadjuvant Long-course Chemoradiation Plus PD-1 Blockade for Mid-low Locally Advanced Rectal Cancer NCT05245474Phase 28 sites📍 Beijing📍 Beijing📍 Beijing Beijing Friendship Hospital · Tests: Long-course chemoradiation, with or without Tislelizumab (PD-1 inhibitor) Efficacy and Safety Comparison of Short-course Radiotherapy Followed by CapeOX Chemotherapy Plus Toripalimab With or Without Concurrent Surufatinib in Neoadjuvant Therapy for Mid-to-low Localized Rectal Cancer of High-risk Criteria NCT07505472Phase 2, Phase 31 site📍 Changchun The First Hospital of Jilin University · Tests: Experimental Group, Control group Intraoperative Rectal Lavage to Prevent Local Recurrence After Laparoscopic Mid-to-Low Rectal Cancer Resection: A Multicenter Randomized Trial NCT07512232NA1 site📍 Guangzhou Sun Yat-sen University · Tests: Rectal irrigation Tamsulosin for Early Catheter Removal After Rectal Cancer Surgery NCT07346586NA2 sites📍 Harbin📍 Changchun The First Hospital of Jilin University · Tests: Tamsulosin group, 24-Hour Removal Group, 48-Hour Removal Group Node-Sparing Short-Course Radiation Combined With Capecitabine and PD-1/CTLA-4 for MSS Early Rectal Cancer NCT07068763Phase 21 site📍 Hangzhou Sir Run Run Shaw Hospital · Tests: Lymph-node-sparing short-course radiotherapy, Capecitabine, PD-1/CTLA-4 inhibitor (Aiparolitoworixureli injection) A Single-center, Phase II Study on Efficacy & Safety of SCRT+CAPOX+Serplulimab+Bevacizumab for MSS Rectal Cancer NCT07347951Phase 21 site📍 Wenzhou First Affiliated Hospital of Wenzhou Medical University · Tests: Short-course radiotherapy, CAPOX chemotherapy, Targeted therapy with bevacizumab, Serplulimab immunotherapy Node-sparing Radiotherapy Combined With Total Neoadjuvant CAPOX and Sintilimab for MSS Middle and Low Rectal Cancer NCT06204094Phase 21 site📍 Jinhua Jinhua Central Hospital · Tests: node-sparing short-course radiotherapy, Sintilimab, Capecitabine, Oxaliplatin, TME surgery Node-Sparing Short-Course Radiotherapy Sequential Chemotherapy and PD-1 Inhibitor for Mid/Low pMMR/MSS Rectal Cancer (MODIFI-RC-II) NCT06958432Phase 2, Phase 31 site📍 Guangzhou Sixth Affiliated Hospital, Sun Yat-sen University · Tests: Node-Sparing Radiotherapy plus Chemotherapy and PD-1 inhibitor, Conventional Radiotherapy plus Chemotherapy Modified Long-Course Radiotherapy Followed by Chemotherapy and PD-1 Inhibitor for MSS/pMMR High-risk Mid/Low LARC (MODIFI-RC-I) NCT06923345Phase 21 site📍 Guangzhou Sixth Affiliated Hospital, Sun Yat-sen University · Tests: Reduced CTV, Conventional CTV
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