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Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Myelodysplastic Syndrome(MDS)

Registry of Myelodysplastic Syndromes and Therapy-related Acute Myeloid Leukemia NCT06956755n/a1 site๐Ÿ“ Rouen Groupe Francophone des Myelodysplasies Chemotherapy (Decitabine in Combination With FLAG-Ida) and Total-Body Irradiation Followed by Donor Stem Cell Transplant for the Treatment of Adults With Myeloid Malignancies at High Risk of Relapse NCT06928662Phase 1, Phase 21 site๐Ÿ“ Seattle Fred Hutchinson Cancer Center ยท Tests: Decitabine, Bone Marrow Aspiration, Bone Marrow Biopsy, Chest Radiography, Cytarabine Fludarabine Phosphate, Cytarabine, Filgrastim-sndz, Gemtuzumab Ozogamicin, and Idarubicin Hydrochloride in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome NCT00801489Phase 21 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Cytarabine, Decitabine, Filgrastim-sndz, Fludarabine Phosphate, Gemtuzumab Ozogamicin Monitoring Mutational Burden in Low Risk MDS Patients Using Sequential Peripheral Blood Samples NCT04251078n/a1 site๐Ÿ“ Badalona Josep Carreras Leukaemia Research Institute Investigation of the Genetics of Hematologic Diseases NCT02720679n/a1 site๐Ÿ“ Memphis St. Jude Children's Research Hospital A Phase 2 Study Evaluating Olutasidenib in Patients With IDH1-mutated Clonal Cytopenia of Undetermined Significance and Lower-risk Myelodysplastic/Syndromes/Chronic Myelomonocytic Leukemia. NCT06566742Phase 22 sites๐Ÿ“ Miami๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Olutasidenib Intestinal Microbiota Transplant Prior to Allogeneic Stem Cell Transplant (MAST) Trial NCT06355583Phase 28 sites๐Ÿ“ Birmingham๐Ÿ“ Leeds๐Ÿ“ London Imperial College London ยท Tests: EBX-102, Placebo Curcumin to Improve Inflammation and Symptoms in Patients With Clonal Cytopenia of Undetermined Significance, Low Risk Myelodysplastic Syndrome, and Myeloproliferative Neoplasms NCT06063486Phase 22 sites๐Ÿ“ Los Angeles๐Ÿ“ Los Angeles University of Southern California ยท Tests: Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy, Curcumin/ Demethoxycurcumin/Bisdemethoxycurcumin-coโ€ฆ Age-Stratified Conditioning Regimen Efficacy for MDS Haplo-HSCT NCT07677306Phase 21 site๐Ÿ“ Beijing Peking University People's Hospital ยท Tests: RTC conditioning regimen and Modified Bu/Cy conditioning regimen Venetoclax in Addition to Sequential Conditioning With Fludarabine / Amsacrine / Ara-C (FLAMSA) + Treosulfan for Allogeneic Blood Stem Cell Transplantation in Patients With MDS, CMML or sAML NCT05807932Phase 1, Phase 26 sites๐Ÿ“ Aachen๐Ÿ“ Dรผsseldorf๐Ÿ“ Cologne Heinrich-Heine University, Duesseldorf ยท Tests: Venetoclax, Amsacrine, Ara-C, Tacrolimus, Mycophenolate Mofetil Trial of 2 Step ATG for Acute GVHD Prevention Post Myeloablative Allogeneic Stem Cell Transplant NCT06315309Phase 21 site๐Ÿ“ Birmingham University of Alabama at Birmingham ยท Tests: ATG Combined with Tacrolimus and Mini Methotrexate Efficacy of Immediate Allogeneic Hematopoietic Stem Cell Transplantation Versus Bridging Therapy Followed by Transplantation in Higher-Risk Myelodysplastic Syndrome Patients NCT06918834Phase 25 sites๐Ÿ“ Beijin๐Ÿ“ Zhengzhou๐Ÿ“ Jinan Institute of Hematology & Blood Diseases Hospital, China ยท Tests: Immediate HSCT Group, Bridging Therapy Group Olutasidenib for the Treatment of Patients With IDH1 Mutated AML, MDS or CMML After Donor Hematopoietic Cell Transplant NCT06543381Phase 12 sites๐Ÿ“ Duarte๐Ÿ“ Cleveland City of Hope Medical Center ยท Tests: Biospecimen Collection, Olutasidenib A Study to Assess the Effectiveness and Safety of Pacritinib in Patients With VEXAS Syndrome (PAXIS) NCT06782373Phase 239 sites๐Ÿ“ Scottsdale๐Ÿ“ Boston๐Ÿ“ Rochester Swedish Orphan Biovitrum ยท Tests: Pacritinib, Placebo Q702 for the Treatment of Patients With Hematologic Malignancies NCT06712810Phase 12 sites๐Ÿ“ Scottsdale๐Ÿ“ Rochester Mayo Clinic ยท Tests: Axl/Mer/CSF1R Inhibitor Q702, Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy, Computed Tomography CPX-351 in Treating Patients With Relapsed or Refractory High Risk Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia NCT03896269Phase 11 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Liposome-encapsulated Daunorubicin-Cytarabine Cord Blood Transplantation in Children and Young Adults With Blood Cancer NCT07566377Phase 21 site๐Ÿ“ New York Memorial Sloan Kettering Cancer Center ยท Tests: Cord Blood Units, Total Body Irradiation, Cyclophosphamide, Fludarabine, Clofarabine A Phase II Study of Allogeneic Hematopoietic Stem Cell Transplant for Subjects With VEXAS (Vacuoles, E1 Enzyme, X-linked, Autoinflammatory, Somatic) Syndrome NCT05027945Phase 21 site๐Ÿ“ Bethesda National Cancer Institute (NCI) ยท Tests: Allogeneic HSCT, Busulfan test dose, Mycophenolate mofetil (MMF), Tacrolimus, Busulfan Allo HSCT Using RIC and PTCy for Hematological Diseases NCT05805605Phase 21 site๐Ÿ“ Minneapolis Masonic Cancer Center, University of Minnesota ยท Tests: Peripheral Blood Stem Cell Transplant, Allopurinol 300 MG, Fludarabine, Cyclophosphamide, Bone Marrow Cell Transplant The Prospective Collection, Storage and Reporting of Data on Patients Undergoing Hematopoietic Stem Cell Transplantation Utilizing a Standard Preparative Regimen NCT01890486n/a1 site๐Ÿ“ Winston-Salem Wake Forest University Health Sciences A Phase Ib Study of APG-115 Single Agent or in Combination With Azacitidine or Cytarabine in Patients With AML and MDS. NCT04275518Phase 114 sites๐Ÿ“ Beijing๐Ÿ“ Guangzhou๐Ÿ“ Guangzhou Ascentage Pharma Group Inc. ยท Tests: APG-115, Azacitidine, Cytarabine Autologous T Cells Transduced With Retroviral Vectors Expressing TCRs for Participant-specific Neoantigens in Patients With Hematologic Malignancies NCT06904066Phase 11 site๐Ÿ“ Bethesda National Cancer Institute (NCI) ยท Tests: aldesleukin, cyclophosphamide, fludarabine phosphate, Individual Patient TCR-Transduced PBL, TruSight Oncology (TSO) 500 Institut Paoli Calmettes Myelodysplastic Syndromes Database NCT03275480n/a1 site๐Ÿ“ Marseille Institut Paoli-Calmettes Iadademstat With Hypomethylating Agent in Patients With Myelodysplastic Syndrome NCT06502145Phase 11 site๐Ÿ“ Milwaukee Medical College of Wisconsin ยท Tests: Azacitidine Level -1, Azacitidine Level 0, Azacitidine Level 1, Iadademstat Level -1, Iadademstat Level 0 Ruxolitinib With Tacrolimus and Methotrexate for the Prevention of Graft Versus Host Disease in Pediatric and Young Adult Patients Undergoing Allogeneic Hematopoietic Cell Transplant for Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, or Myelodysplastic Syndrome NCT06128070Phase 21 site๐Ÿ“ Duarte City of Hope Medical Center ยท Tests: Biospecimen Collection, Chest Computed Tomography, Echocardiography, Hematopoietic Cell Transplantation, Methotrexate A Trial Testing SP-420 in Subjects With Transfusion-dependent ฮฒ-thalassemia or Low-risk Myelodysplastic Syndromes NCT05693909Phase 21 site๐Ÿ“ Copenhagen Pharmacosmos A/S ยท Tests: SP-420 Venetoclax Basket Trial for High Risk Hematologic Malignancies NCT05292664Phase 15 sites๐Ÿ“ San Francisco๐Ÿ“ Aurora๐Ÿ“ Atlanta Andrew E. Place, MD ยท Tests: Venetoclax, Azacitidine, Cytarabine, Methotrexate, Hydrocortisone Clinical Study of ARD103 CAR-T Therapy for Patients With R/R AML or MDS NCT06680752Phase 1, Phase 23 sites๐Ÿ“ Charlotte๐Ÿ“ Winston-Salem๐Ÿ“ Houston ARCE Therapeutics, Inc. ยท Tests: ARD103, Cyclophosphamide, Fludarabine A Phase 1B/2A Trial of NADUNOLIMAB in Combination With Azacitidine (With/Without Venetoclax) in Patients With Myelodysplastic Syndrome (MDS) and Acute Myelogenous Leukemia (AML) NCT06548230Phase 1, Phase 21 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Nadunolimab, Azacitidine, Venetoclax Venetoclax to Improve Outcomes of Fractionated Busulfan Regimen in Patients With High-Risk AML and MDS NCT04708054Phase 2, Phase 31 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Busulfan, Cladribine, Fludarabine Phosphate, Hematopoietic Cell Transplantation, Thiotepa
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