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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for NSCLC, Stage I

To Explore the Safety and Efficacy of Hypervision Proton Surgery for Early-stage Non-small Cell Lung Cancer NCT07195084NA1 site๐Ÿ“ Hefei Anhui Provincial Cancer Hospital ยท Tests: Hypervision proton surgery A Phase I Study of CFT8919 in Patients With Advanced NSCLC NCT06641609Phase 11 site๐Ÿ“ Hangzhou Betta Pharmaceuticals Co., Ltd. ยท Tests: Dose-Escalation (Phase Ia) CFT8919 capsule, Dose-Expansion (Phase Ib) CFT8919 capsule, Cohort-Expansion (Phase Ic) CFT8โ€ฆ Collecting and Analyzing Tissue Samples From Patients Undergoing Surgery for Non-Small Cell Lung Cancer NCT00897117n/a3 sites๐Ÿ“ Nashville๐Ÿ“ Nashville๐Ÿ“ Nashville Vanderbilt-Ingram Cancer Center ยท Tests: gene expression analysis, microarray analysis, protein expression analysis, biologic sample preservation procedure, labโ€ฆ TT-702 in Patients With Advanced Solid Tumours. NCT05272709Phase 1, Phase 23 sites๐Ÿ“ London๐Ÿ“ Manchester๐Ÿ“ Southampton Cancer Research UK ยท Tests: TT-702, Anti-PD-1 and PD-L1 agent Anti-Ly6E Exatecan ADC M7437 in Advanced Solid Tumors NCT07360314Phase 19 sites๐Ÿ“ New Haven๐Ÿ“ Huntersville๐Ÿ“ Galveston EMD Serono Research & Development Institute, Inc. ยท Tests: M7437, M7437 Sotorasib in Combination With Trastuzumab Deruxtecan for the Treatment of Locally Advanced and Metastatic Non-small Cell Lung Cancer With a KRAS G12C Mutation NCT07012031Phase 1, Phase 29 sites๐Ÿ“ Sacramento๐Ÿ“ Tampa๐Ÿ“ Tampa National Cancer Institute (NCI) ยท Tests: Biopsy Procedure, Biospecimen Collection, Computed Tomography, Echocardiography Test, Magnetic Resonance Imaging The Impact of Surgical Technique on Circulating Tumor DNA in Stage I-III Non-Small Cell Lung Cancer NCT05502523NA4 sites๐Ÿ“ Abington๐Ÿ“ Philadelphia๐Ÿ“ Philadelphia Thomas Jefferson University ยท Tests: Pulmonary Artery-First Surgical Technique, Biospecimen Collection Understanding the Feasibility of a Co-designed Pre-radiotherapy Exercise Programme - A Single-arm Study NCT07554677NA1 site๐Ÿ“ Belfast Queen's University, Belfast ยท Tests: Exercise, radiotherapy Vebreltinib Plus Furmonertinib in Patients With EGFR-mutated Advanced Non-small Cell Lung Cancer and High PD-L1 Expression NCT07655622Phase 1, Phase 21 site๐Ÿ“ Nanchang Second Affiliated Hospital of Nanchang University ยท Tests: Vebreltinib, Furmonertinib 80mg Adjuvant Therapy of Ensartinib in Stage IB-IIIA ALK-positive Non-small Cell Lung Cancer NCT05241028Phase 21 site๐Ÿ“ Shijiazhuang Hebei Medical University Fourth Hospital ยท Tests: Ensartinib First in Human Study of TUB-030 in Patients With Advanced Solid Tumors NCT06657222Phase 1, Phase 220 sites๐Ÿ“ New Haven๐Ÿ“ Miami๐Ÿ“ Boston Gilead Sciences ยท Tests: TUB-030 Efficacy and Safety of a Single Dose of LS301-IT for Fluorescence Intraoperative Molecular Imaging (IMI) for Patients Undergoing Lung Cancer Resection for Non Small Cell Lung Cancer NCT07276789Phase 22 sites๐Ÿ“ Philadelphia๐Ÿ“ Dallas Integro Theranostics ยท Tests: LS301-IT 0.1 mg/kg Safety and Efficacy of NK510 to Treat NSCLC NCT06097962EARLY Phase 11 site๐Ÿ“ Nanjing Base Therapeutics (Shanghai) Co., Ltd. ยท Tests: NK510, Tislelizumab๏ผŒatezolizumab or sugemalimab, NK510, systemic therapy as selected by the investigator Surgery With or Without Chemotherapy for Stage I NSCLC With Micropapillary Component โ‰ฅ 20% NCT03351842Phase 21 site๐Ÿ“ Shanghai Shanghai Pulmonary Hospital, Shanghai, China ยท Tests: cis Platinum/Carboplatin, Pemetrexed Disodium, Undergo surgery A Phase I Dose Escalation and Dose Expansion Study to Investigate the Pharmacokinetics and Safety of Subcutaneous Durvalumab NCT07391670Phase 119 sites๐Ÿ“ Fitzroy๐Ÿ“ St Albans๐Ÿ“ Woolloongabba AstraZeneca ยท Tests: SC durvalumab + rHu, IV durvalumab, Tremelimumab Synapse 3D With Intravascular Indocyanine Green NCT03953144Phase 1, Phase 21 site๐Ÿ“ Hamilton St. Joseph's Healthcare Hamilton ยท Tests: Synapse 3D Lung Modelling, IC-Green (ICG) Study of Osimertinib With Carotuximab in Advanced, EGFR-mutated Non-Small Cell Lung Cancer NCT05401110Phase 15 sites๐Ÿ“ Beverly Hills๐Ÿ“ Los Angeles๐Ÿ“ Los Angeles Karen Reckamp, MD, MS ยท Tests: Osimertinib, Carotuximab Testing the Impact of an Anti-Cancer Drug, Atezolizumab, After Surgery to Prevent Early Stage Non-small Cell Lung Cancer From Returning, AASI-NSCLC Trial NCT07388524Phase 3110 sites๐Ÿ“ Beverly Hills๐Ÿ“ Los Angeles๐Ÿ“ Tarzana National Cancer Institute (NCI) ยท Tests: Atezolizumab, Atezolizumab and Recombinant Human Hyaluronidase, Biospecimen Collection, Computed Tomography, Patient Obโ€ฆ Phase I Study of HSK40118 in NSCLC Patients With EGFR Mutation NCT06050980Phase 112 sites๐Ÿ“ Beijing๐Ÿ“ Chongqing๐Ÿ“ Fuzhou Haisco Pharmaceutical Group Co., Ltd. ยท Tests: HSK40118 A Study of EP0031 (Lunbotinib) in Patients With Advanced RET-altered Malignancies NCT05443126Phase 1, Phase 252 sites๐Ÿ“ Los Angeles๐Ÿ“ Stanford๐Ÿ“ Washington D.C. Ellipses Pharma ยท Tests: EP0031, Platinum chemotherapy, Pemetrexed Osimertinib Therapy After Resection in High-risk Stage I EGFRm NSCLC (OSTAR) NCT05686434Phase 21 site๐Ÿ“ Tianjin Tianjin Medical University Cancer Institute and Hospital ยท Tests: Osimertinib TCR-T Cell Immunotherapy of Lung Cancer and Other Solid Tumors NCT03778814Phase 11 site๐Ÿ“ Guanzhou Second Affiliated Hospital of Guangzhou Medical University ยท Tests: TCR-T cells MOv19-BBz CAR T Cells in FRa+ Cancers NCT07116057Phase 11 site๐Ÿ“ Philadelphia University of Pennsylvania ยท Tests: MOv19-BBz CAR T cells, Cyclophosphamide/Fludarabine, FRa Expression Testing Anti-NY-ESO-1 TCR-Gene Engineered Lymphocytes Given by Infusion to Patients With NY-ESO-1 -Expressing Metastatic Cancers NCT05296564Phase 1, Phase 21 site๐Ÿ“ Jerusalem Hadassah Medical Organization ยท Tests: CYCLOPHOSPHAMIDE and FLUDARABIN, Cyclophosphamide, HBI 0201-ESO TCRT, Aldesleukin Study of Oral EGFR Inhibitor DZD6008 Combined With Sunvozertinib in Patients Who Have Advanced NSCLC With EGFR Mutations (TIAN-SHAN8) NCT07079475Phase 1, Phase 214 sites๐Ÿ“ Beijing๐Ÿ“ Guangzhou๐Ÿ“ Harbin Dizal Pharmaceuticals ยท Tests: DZD6008, Sunvozertinib, Osimertinib RAPA-201 Therapy of Solid Tumors NCT05144698Phase 1, Phase 21 site๐Ÿ“ Hackensack Rapa Therapeutics LLC ยท Tests: RAPA-201 Rapamycin Resistant T Cells, Chemotherapy Prior to RAPA-201 Therapy, Pembrolizumab (PD-1 Blocking Antibody) Phase I Study of Tolododekin Alfa (ANK-101) in Advanced Solid Tumors NCT06171750Phase 15 sites๐Ÿ“ Bethesda๐Ÿ“ Boston๐Ÿ“ Portland Ankyra Therapeutics, Inc ยท Tests: tolododekin alfa, Cemiplimab Adjuvant Benmelstobart for Stage IB, Grade 3 Invasive Lung Adenocarcinoma NCT06528847Phase 21 site๐Ÿ“ Shanghai Shanghai Pulmonary Hospital, Shanghai, China ยท Tests: Benmelstobart Split Course Adaptive Radiation Therapy With Pembrolizumab With/Without Chemotherapy for Treating Stage IV Lung Cancer NCT05501665Phase 1, Phase 21 site๐Ÿ“ Nashville Vanderbilt-Ingram Cancer Center ยท Tests: Biospecimen Collection, Carboplatin, Computed Tomography, Fludeoxyglucose F-18, Nab-paclitaxel Induction Chemoimmunotherapy in Combination With Chemoradiotherapy and Consolidation Immunotherapy in Unresectable Locally Advanced Non-Small Cell Lung Cancer NCT07632365Phase 1, Phase 21 site๐Ÿ“ Shanghai Shanghai Chest Hospital ยท Tests: Induction chemoimmunotherapy, Concurrent chemoradiotherapy (cCRT), consolidation immunotherapy
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