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Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Nasopharyngeal Cancer Recurrent

Clinical Study on the EBV CAR-T /TCR-T Cells in the Treatment of Nasopharyngeal Carcinoma NCT05587543EARLY Phase 11 site๐Ÿ“ Shanghai Fudan University ยท Tests: PK Blood Collection, CAR, TCR EGFR Antibody Combined With PD-1 Inhibitor and Chemotherapy in R/M Nasopharyngeal Carcinoma NCT06802835Phase 1, Phase 21 site๐Ÿ“ Guangzhou Sun Yat-sen University ยท Tests: EGFR Antibody, PD-1 antibody, Gemcitabine, Cisplatin, IMRT Irinotecan Liposome Combined with S-1 in PD-1/L1 Inhibitor Refractory Recurrent or Metastatic NPC NCT06657690Phase 21 site๐Ÿ“ Zhuhai Sun Yat-sen University ยท Tests: Irinotecan liposome, S-1 A Study of MRG003 in Combination With Pucotenlimab Versus Chemotherapy in the Treatment of Patients With Recurrent or Metastatic Nasopharyngeal Carcinoma NCT06976190Phase 31 site๐Ÿ“ Guangzhou Lepu Biopharma Co., Ltd. ยท Tests: MRG003 + Pucotenlimab, Gemcitabine, Docetaxel, or Capecitabine MRG003 Induction and Capecitabine Maintenance With PD-1 in Locally Recurrent NPC NCT07331428Phase 21 site๐Ÿ“ Fuzhou Fujian Cancer Hospital ยท Tests: MRG003, Tislelizumab, Capecitabine Toripalimab Plus Surgery vs Surgery Alone for Resectable Recurrent Nasopharyngeal Carcinoma NCT04778956Phase 37 sites๐Ÿ“ Guangzhou๐Ÿ“ Guangzhou๐Ÿ“ Guangzhou Sun Yat-sen University ยท Tests: Toripalimab, salvage surgery TMV Vaccine Therapy Alone and With Pembrolizumab for the Treatment of Recurrent and/or Metastatic Head and Neck Squamous Cell Cancer NCT06868433Phase 12 sites๐Ÿ“ Atlanta๐Ÿ“ Atlanta Emory University ยท Tests: Autologous Tumor Membrane Vesicles Vaccine, Biospecimen Collection, Computed Tomography, Echocardiography, Magnetic Resโ€ฆ Investigation of Multi-omics Technique to Predict the Efficacy of Chemoradiotherapy Combined With Immunotherapy for r/m NPC NCT06197776n/a1 site๐Ÿ“ Guangzhou Sun Yat-sen University ยท Tests: cisplatin-based chemoradiotherapy combined with immunotherapy Docetaxel and SX-682 in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma, Salivary Gland Carcinoma, and Advanced Prostate Cancer NCT07667400Phase 1, Phase 21 site๐Ÿ“ Bethesda National Cancer Institute (NCI) ยท Tests: SX-682, DTX Becotatug Vedotin Combined With a PD-1 Inhibitor in the Treatment of Locally Advanced Recurrent Nasopharyngeal Carcinoma. NCT07781358Phase 21 site๐Ÿ“ Shanghai Hongmeng Yu ยท Tests: Becotatug Vedotin, PD-1 / PD-L1 monoclonal antibody A Multi-center, Randomized, Double-blind, Phase II/III Clinical Trial of AK104 or Placebo in Combination With Chemotherapy as Second-line or More Lines for Recurrent or Metastatic Nasopharyngeal Carcinoma (NPC) NCT06241599Phase 2, Phase 31 site๐Ÿ“ Guangzhou Sun Yat-sen University ยท Tests: GP/PFLL+AK104, GP/PFLL+placebo SBRT and LDRT Combined With PD-1 Antibody and Chemotherapy in r/m Nasopharyngeal Carcinoma NCT06323239Phase 21 site๐Ÿ“ Guangzhou Sun Yat-sen University ยท Tests: SBRT, Low-dose Radiotherapy (LDRT), Toripalimab, Gemcitabine, Cisplatin TN Induction and Adjuvant Therapy for Resectable Local Recurrent Nasopharyngeal Carcinoma NCT06912711Phase 21 site๐Ÿ“ Guangzhou Sun Yat-sen University ยท Tests: Toripalimab, Nimotuzumab, surgery Deep Learning-based sbORN Diagnostic Model NCT06463392n/a1 site๐Ÿ“ Guangzhou Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University ยท Tests: No Intervention: Observational Cohort JS207 a Bispecific Antibody Against PD1-VEGF in Nasopharyngeal Carcinoma NCT07690787Phase 21 site๐Ÿ“ Hong Kong Chinese University of Hong Kong ยท Tests: JS207, Paclitaxel, Capecitabine Tissue Sample Collection From Patients With Head and Neck Cancer and From Healthy Participants NCT00898638n/a4 sites๐Ÿ“ Nashville๐Ÿ“ Nashville๐Ÿ“ Nashville Vanderbilt University Medical Center ยท Tests: biologic sample preservation procedure, medical chart review Toripalimab Plus Concurrent Chemo-radiotherapy for Unresectable Locally Recurrent Nasopharyngeal Carcinoma NCT04453813Phase 36 sites๐Ÿ“ Guangzhou๐Ÿ“ Guangzhou๐Ÿ“ Shaoguan Sun Yat-sen University ยท Tests: Toripalimab plus concurrent chemo-radiotherapy, Concurrent chemo-radiotherapy Phase I Study of Becotatug Vedotin for Safety and Efficacy in EGFR-Positive Pediatric Relapsed/Refractory or Metastatic Solid Tumors NCT07584499Phase 11 site๐Ÿ“ Guangzhou Sun Yat-sen University ยท Tests: Becotatug Vedotin Intratumoral Injection of Recombinant Human Endostatin Adenovirus (EDS01) for the Treatment of Recurrent or Metastatic Head and Neck Tumors NCT07625423Phase 11 site๐Ÿ“ Chengdu West China Hospital ยท Tests: EDS01 1.0ร—10^11 VP + Toripalimab, EDS01 5.0ร—10^11 VP + Toripalimab, EDS01 1.0ร—10^12 VP + Toripalimab Chemoradiotherapy Plus Anti-PD1 in Recurrent NPC: A Multicenter, Open-label, Randomised, Controlled, Phase III Trial NCT05340491Phase 312 sites๐Ÿ“ Guangzhou๐Ÿ“ Beijing๐Ÿ“ Chengdu Sun Yat-sen University ยท Tests: Toripalimab, Chemotherapy, Intensity modulated radiotherapy Association Between Health Care Provider (HCP)-Assessed ECOG Performance Status (PS) and Overall Survival, and Objectively Measure of Physical Activity (PA) Levels in Advance-cancer Patients" NCT01365169NA1 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Exercise Intervention, Health Telemonitoring, Health Telemonitoring, Health Telemonitoring, Health Telemonitoring Clinical Trial of SIBP-03 in Patients With Head and Neck Squamous Cell Carcinoma NCT06194656Phase 22 sites๐Ÿ“ Shanghai๐Ÿ“ Shanghai Shanghai Institute Of Biological Products ยท Tests: HER3 Monoclonal antibodies-Dose A, HER3 Monoclonal antibodies-Dose B, HER3 Monoclonal antibodies-Dose C, HER3 Monoclonaโ€ฆ Clinical Study of Mitoxantrone Hydrochloride Liposome Combined with PD-1 Blockade in Recurrent or Metastatic NPC NCT06472713Phase 21 site๐Ÿ“ Zhuhai Ming-Yuan Chen ยท Tests: Mitoxantrone hydrochloride liposome injection, PD-1 Inhibitors Neoadjuvant vs Adjuvant in Locally Advanced Recurrent NPC NCT06235203Phase 37 sites๐Ÿ“ Shanghai๐Ÿ“ Fuzhou๐Ÿ“ Nanning Eye & ENT Hospital of Fudan University ยท Tests: endoscopic surgery, Neoadjuvant therapy,Toripalimab Injection and Gemcitabine based therapy, Adjuvant therapy in experiโ€ฆ PD-1 Inhibitor Plus Chemotherapy Followed by Immediate Versus Selective Re-irradiation for Locally Advanced Recurrent NPC NCT07332247Phase 21 site๐Ÿ“ Guangzhou Sun Yat-sen University ยท Tests: Selective re-irradiation, Immediate re-irradiation SBRT Combined With Nimotuzumab and Tislelizumab for Oligoprogressive Recurrent/Metastatic Nasopharyngeal Carcinoma After Failure of Immunotherapy NCT06676722Phase 22 sites๐Ÿ“ Xiamen๐Ÿ“ Xiamen The First Affiliated Hospital of Xiamen University ยท Tests: SBRT combined with Nimotuzumab followed by Tislelizumab Testing Whether Cemiplimab (REGN2810) Plus CDX-1140 Given Prior to Surgery Are Better Than Cemiplimab (REGN2810) Alone in Patients With Stage III-IV Head and Neck Cancer NCT06980038Phase 212 sites๐Ÿ“ Irvine๐Ÿ“ Los Angeles๐Ÿ“ Los Angeles National Cancer Institute (NCI) ยท Tests: Anti-CD40 Agonist Monoclonal Antibody CDX-1140, Biopsy Procedure, Biospecimen Collection, Cemiplimab, Computed Tomograpโ€ฆ Combination Therapy for PD-1 Resistant Recurrent or Metastatic Nasopharyngeal Carcinoma: A Bayesian Adaptive Phase II Trial NCT07070479Phase 26 sites๐Ÿ“ Guangzhou๐Ÿ“ Guangzhou๐Ÿ“ Guangzhou Ming-Yuan Chen ยท Tests: Ivonescimab, Nimotuzumab, Irinotecan liposome, S-1, Mitoxantrone Hydrochloride Liposome Adjuvant vs Surgery Only in Early-stage Recurrent NPC NCT06228079Phase 37 sites๐Ÿ“ Shanghai๐Ÿ“ Fuzhou๐Ÿ“ Nanning Eye & ENT Hospital of Fudan University ยท Tests: Immunotherapy,Toripalimab Injection, Chemotherapy,Gemcitabine based regimen Concurrent Chemotherapy for Recurrent T3/T4 Nasopharyngeal Carcinoma NCT04136886Phase 31 site๐Ÿ“ Guangzhou Sun Yat-sen University ยท Tests: Cisplatin, IMRT
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