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Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Neuromyelitis Optica

Rituximab Versus Ravulizumab, Inebilizumab, Satralizumab, and Eculizumab in NMOSD NCT07010302Phase 43 sites๐Ÿ“ Boston๐Ÿ“ Boston๐Ÿ“ Berlin Massachusetts General Hospital ยท Tests: Rituximab (R), Eculizumab (Solirisยฎ), Ravulizumab, Satralizumab, Inebilizumab A Study to Evaluate Pharmacokinetics, Efficacy, Safety, Tolerability, and Pharmacodynamics of Satralizumab in Pediatric Patients With Aquaporin-4 Antibody Positive Neuromyelitis Optica Spectrum Disorder (NMOSD) NCT05199688Phase 314 sites๐Ÿ“ Denver๐Ÿ“ Ciudad Autonoma Buenos Aires๐Ÿ“ Cรณrdoba Hoffmann-La Roche ยท Tests: Satralizumab Clinical Impact Through AI-assisted MS Care - A Retrospective Multi-center Observational Study. NCT06280755n/a3 sites๐Ÿ“ Prague๐Ÿ“ Bochum๐Ÿ“ Berlin icometrix Universal Chimeric Antigen Receptor T-Cell ๏ผˆUCAR T-cell๏ผ‰ Therapy Targeting CD19/B Cell Maturation Antigen ๏ผˆCD19/BCMA๏ผ‰ in Patients With r/r Neurological Autoimmune Diseases NCT06939166EARLY Phase 11 site๐Ÿ“ Tianjin Tianjin Huanhu Hospital ยท Tests: UCAR T-cell Monoclonal Antibody-Based Therapies for AQP4-Positive NMOSD NCT06885957n/a1 site๐Ÿ“ Wuhan Tongji Hospital ยท Tests: Mab Therapy Study of Inebilizumab in Pediatric Subjects With Neuromyelitis Optica Spectrum Disorder NCT05549258Phase 219 sites๐Ÿ“ La Jolla๐Ÿ“ Loma Linda๐Ÿ“ Boston Amgen ยท Tests: Inebilizumab Impact of a Structured Wellness Behavioral Intervention on Quality of Life in NMOSD NCT06780709NA1 site๐Ÿ“ New York Icahn School of Medicine at Mount Sinai ยท Tests: Wellness Program and Behavioral Counseling Therapy in the Acute Phase of NMOSD: A Multicenter Prospective Real-World Study NCT07410039Phase 41 site๐Ÿ“ Beijing Chinese PLA General Hospital ยท Tests: Eculizumab+IVMP, IVIG+IVMP, IVMP A Clinical Study of B001 Injection in the Treatment of Neuromyelitis Optica Spectrum Disorders(NMOSD) NCT06413654Phase 2, Phase 351 sites๐Ÿ“ Beijing๐Ÿ“ Beijing๐Ÿ“ Beijing Shanghai Jiaolian Drug Research and Development Co., Ltd ยท Tests: B001, Placebo Phase 1 Study of HBI0101 CAR-T in Refractory B-Cell Autoimmune Diseases NCT07085676Phase 11 site๐Ÿ“ Jerusalem Polina Stepensky ยท Tests: HBI0101 CART French Registry for Monitoring Pregnancies for Multiple Sclerosis NCT03900221n/a48 sites๐Ÿ“ Amiens๐Ÿ“ Annecy๐Ÿ“ Avignon Hospices Civils de Lyon ยท Tests: No intervention Observational Safety Study in Women With Neuromyelitis Optica Spectrum Disorder (NMOSD) Exposed to UPLIZNAยฎ During Pregnancy NCT05909761n/a1 site๐Ÿ“ Aurora Amgen ยท Tests: UPLIZNA Cohort Study on Neuroimmune Diseases in the Reproductive Age NCT07653984n/a1 site๐Ÿ“ Guangzhou Third Affiliated Hospital, Sun Yat-Sen University Registry of Patients With AQP4+ NMOSD Treated With Alexion C5 Inhibitor Therapies NCT05966467n/a33 sites๐Ÿ“ Washington D.C.๐Ÿ“ Boston๐Ÿ“ Chapel Hill Alexion Pharmaceuticals, Inc. HANDLE-a Real World Study on Satralizumab in NMOSD NCT06829524n/a1 site๐Ÿ“ Shanghai Huashan Hospital ยท Tests: Satralizumab Ofatumumab in AQP4-IgG Seropositive NMOSD NCT05504694Phase 1, Phase 21 site๐Ÿ“ Xi'an Tang-Du Hospital ยท Tests: Ofatumumab A Study of C-CAR168 in the Treatment of Autoimmune Diseases Refractory to Standard Therapy NCT06249438Phase 11 site๐Ÿ“ Shanghai RenJi Hospital ยท Tests: CD20/BCMA-directed CAR-T cells Efficacy, Safety, Pharmacokinetics, Pharmacodynamics, and Immunogenicity Study of Ravulizumab in Chinese Adults With Neuromyelitis Optica Spectrum Disorder (NMOSD) NCT07557420Phase 310 sites๐Ÿ“ Beijing๐Ÿ“ Beijing๐Ÿ“ Chengdu Alexion Pharmaceuticals, Inc. ยท Tests: Ravulizumab Frequency of FCGR3A Gene Polymorphisms in Patients With Neuromyelitis Optica Spectrum Disorders, Anti-oligodendrocyte Myelin Protein Antibody Disease, and Multiple Sclerosis. NCT06865274NA1 site๐Ÿ“ Roma Fondazione Policlinico Universitario Agostino Gemelli IRCCS ยท Tests: Blood draw for the laboratory assessment Efgartigimod for the Treatment of Acute Optic Neuritis NCT06453694Phase 22 sites๐Ÿ“ Boston๐Ÿ“ Boston Anastasia Vishnevetsky, MD, MPH ยท Tests: Efgartigimod Alfa, Placebo The Safety and Efficacy of NouvSoma001 in Neuromyelitis Optica Spectrum Disorders NCT06620809Phase 11 site๐Ÿ“ Wuhan Tongji Hospital ยท Tests: Extracellular vesicles derived from human-induced neural stem cells for intrathecal injection, A placebo of extracellulโ€ฆ Study of the Clinical and Radiological Impact of Ravulizumab in People With Neuromyelitis Optica Spectrum Disorder NCT06398158n/a1 site๐Ÿ“ Dallas University of Texas Southwestern Medical Center ยท Tests: Ravulizumab Efficacy and Safety of Calculus Bovis Sativus (CBS) for Idiopathic Inflammatory Demyelinating Disease (CBSinIIDD) NCT06474520NA1 site๐Ÿ“ Wuhan Tongji Hospital ยท Tests: Calculus bovis sativus (CBS) A Study to Evaluate the Efficacy and Safety of JYP0061 in Patients With Acute Neuromyelitis Spectrum Disease (NMOSD) NCT06697535Phase 21 site๐Ÿ“ Changsha Guangzhou JOYO Pharma Co., Ltd ยท Tests: JYP0061, Intravenous Glucocorticoids, Oral Glucocorticoids Stem Cell Ophthalmology Treatment Study II NCT03011541NA4 sites๐Ÿ“ Westport๐Ÿ“ Coral Springs๐Ÿ“ Vienna MD Stem Cells ยท Tests: Arm 1 Modified Zipper Therapy for AQP4-IgG Positive Neuromyelitis Optica Spectrum Disorder NCT07420296Phase 31 site๐Ÿ“ Tianjin Tianjin Medical University General Hospital ยท Tests: Eculizumab administration, High-dose corticosteroid pulse therapy, Plasma exchange (PE) Biorepository and Registry for Plasma Exchange Patients NCT05004493n/a1 site๐Ÿ“ Iowa City Charles M Knudson Longitudinal Cortical Demyelination in Multiple Sclerosis and Related Disorders NCT05982925n/a1 site๐Ÿ“ New York Icahn School of Medicine at Mount Sinai Safety and Efficacy Study of Sivelestat in Neuromyelitis Optica Spectrum Disorder NCT07738952Phase 1, Phase 21 site๐Ÿ“ Fukuoka Kyushu University ยท Tests: Sivelestat sodium hydrate Clinical and Imaging Cohort of Neuroinflammation Diseases in China (CLUE) NCT04106830n/a1 site๐Ÿ“ Beijing Beijing Tiantan Hospital ยท Tests: Intravenous steroid
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