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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

Know your stage or your test results (such as EGFR, HER2 or BRCA)? Match trials to your own profile - nothing you type is saved.

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30 recruiting trials

for Newly Diagnosed Glioblastoma

Temporally-Modulated Pulsed Radiation Therapy Versus Standard Radiation Therapy for the Treatment of Newly Diagnosed, IDH Wildtype, MGMT-Unmethylated Glioblastoma NCT07452458Phase 354 sites📍 Irvine📍 Los Angeles📍 Orange NRG Oncology · Tests: Biospecimen Collection, Computed Tomography, Magnetic Resonance Imaging, Questionnaire Administration, Radiation Therapy Chemoradiotherapy Versus Chemotherapy for Elderly and Frail GBM Patients NCT04765514Phase 22 sites📍 Calgary📍 Edmonton AHS Cancer Control Alberta · Tests: Temozolomide monotherapy, Chemo-Radiotherapy with concurrent temozolomide. Window of Opportunity Study of Lixumistat in Patients With Newly Diagnosed Glioblastoma NCT07884344EARLY Phase 11 site📍 Miami Macarena De La Fuente, MD · Tests: Lixumistat - Cohort 1, Lixumistat - Cohort 2 Daily Temozolomide for Elderly Patients With Unmethylated MGMT- Promoter Newly Diagnosed GliOblatoma NCT07476794Phase 21 site📍 Toronto Sunnybrook Health Sciences Centre · Tests: Daily TMZ BRiTE - Bispecific T Cell Engager for Patients With Glioblastoma NCT04903795Phase 11 site📍 Durham Mustafa Khasraw, MBChB, MD, FRCP, FRACP · Tests: hEGFRvIII-CD3 (BRiTE) Trial of Glioblastoma Immunotherapy Advancement With Nivolumab and Relatlimab NCT06816927Phase 24 sites📍 New York📍 Durham📍 Houston Duke University · Tests: Nivolumab, Relatlimab, TMZ, Radiation Therapy Ruxolitinib With Radiation and Temozolomide Compared to Radiation and Temozolomide for Newly Diagnosed Glioblastoma NCT06991101Phase 22 sites📍 Miami📍 New York Baptist Health South Florida · Tests: Ruxolitinib, Temozolomide, Radiation Therapy Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIII NCT07326566Phase 235 sites📍 Birmingham📍 Springdale📍 La Jolla Black Diamond Therapeutics, Inc. · Tests: silevertinib in combination with temozolomide, temozolomide (TMZ) Evaluation of Eflornithine Plus Temozolomide in Patients With Newly Diagnosed Glioblastoma or Astrocytoma NCT05879367Phase 18 sites📍 Birmingham📍 Detroit📍 New York Orbus Therapeutics, Inc. · Tests: Eflornithine (Dose Level 1), Eflornithine (Dose Level 2), Eflornithine (Dose Level -1), Temozolomide Intensified Adjuvant Therapy for High-Risk Newly Diagnosed Glioblastoma With Subtotal Resection or Short-Term Progression NCT07670026Phase 21 site📍 Hangzhou Second Affiliated Hospital, Zhejiang University, School of … · Tests: Sintilimab, Bevacizumab, Postoperative Radiotherapy, Temozolomide ONC206 for Treatment of Newly Diagnosed, Recurrent Diffuse Midline Gliomas, and Other Recurrent Malignant CNS Tumors NCT04732065Phase 17 sites📍 San Francisco📍 Washington D.C.📍 Atlanta Sabine Mueller, MD, PhD · Tests: ONC206, Standard of Care Radiation Therapy, Optional Proton (1H) MR spectroscopy (MRS) Study of Low-Intensity Focused Ultrasound in Combination With Immunotherapy in Newly Diagnosed Unmethylated Glioblastoma NCT07343986Phase 11 site📍 Charlottesville University of Virginia · Tests: anti-EGFR bispecific-armed T cells, Low-Intensity Focused Ultrasound DB107-RRV, DB107-FC, and Radiation Therapy With or Without Temozolomide (TMZ) for High Grade Glioma NCT06504381Phase 1, Phase 25 sites📍 Los Angeles📍 San Diego📍 San Francisco University of California, San Francisco · Tests: DB107-RRV, DB107-FC, Radiation Therapy (RT), Temozolomide, Magnetic Resonance Imaging (MRI) Lomustine in Addition to Standard of Care in Patients With MGMT Methylated Glioblastoma NCT06419946Phase 320 sites📍 Graz📍 Innsbruck📍 Linz Vastra Gotaland Region · Tests: Temozolomide, Lomustine A Study of RNA-lipid Particle (RNA-LP) Vaccines for Newly Diagnosed Pediatric High-Grade Gliomas (pHGG) and Adult Glioblastoma (GBM) NCT04573140Phase 12 sites📍 Washington D.C.📍 Gainesville University of Florida · Tests: Autologous total tumor mRNA and pp65 full length (fl) lysosomal associated membrane protein (LAMP) mRNA loaded DOTAP li… D2C7-IT and 2141-V11 in Newly Diagnosed GBM Patients NCT05734560Phase 1, Phase 21 site📍 Durham Darell Bigner · Tests: D2C7-IT, 2141-V11 TMZ + RT + 5-ALA + LIDU SDT System for Newly Diagnosed Butterfly Glioma NCT07862647Phase 11 site📍 Buffalo Alpheus Medical, Inc. · Tests: 5-ALA, Porphyrin Metabolite Activation (PoMA) with LIDU ultrasound Safety and Efficacy of L19TNF Plus Temozolomide Chemoradiotherapy in Patients With Newly Diagnosed Glioblastoma NCT04443010Phase 1, Phase 21 site📍 Zurich Philogen S.p.A. · Tests: Onfekafusp alfa, Temozolomide EF-41/KEYNOTE D58: Phase 3 Study of Optune Concomitant With Temozolomide Plus Pembrolizumab in Newly Diagnosed Glioblastoma NCT06556563Phase 3102 sites📍 Phoenix📍 Los Angeles📍 Newport Beach NovoCure GmbH · Tests: Optune® device, Temozolomide, Pembrolizumab, Placebo A Study to Evaluate the Safety of a Stem Cell-Based Gene and Cell Therapy in Patients With Newly Diagnosed Glioblastoma NCT07143812Phase 11 site📍 Seongnam CHA University · Tests: MSC11FCD Glutamate Inhibitors in Glioblastoma NCT05664464Phase 1, Phase 21 site📍 Zurich University of Zurich · Tests: Gabapentin, Sulfasalazine, Memantine, Temozolomide, Radiotherapy JK-1201I Combined with Adjuvant Temozolomide in Patients with Newly Diagnosed Glioblastoma Multiforme (GBM) NCT06595186Phase 21 site📍 Beijing JenKem Technology Co., Ltd. · Tests: JK-1201I, Temozolomide (TMZ) A Study Assessing if it is Safe and Possible to Treat Brain Cancer Patients With Immunotherapy Before They Receive the Standard Treatment. NCT07134842Phase 11 site📍 London University College, London · Tests: Ipilimumab (3 mg/kg) A Rollover Study of NBM-BMX in Combination With Temozolomide in Patients With Newly Diagnosed Glioblastoma NCT07569042Phase 1, Phase 23 sites📍 Kaohsiung City📍 Taichung📍 Taoyuan City Novelwise Pharmaceutical Corporation · Tests: NBM-BMX Capsule, Temozolomide Enhanced Adjuvant Therapy for Newly Diagnosed GBM With Partial Surgical Resection or Short-term Progression NCT06936046Phase 21 site📍 Hangzhou Second Affiliated Hospital, Zhejiang University, School of … · Tests: Dual antibody A, Dual antibody B, Modified Stupp, Stupp protocol Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant NCT05843253Phase 220 sites📍 Aurora📍 Washington D.C.📍 Chicago Nationwide Children's Hospital · Tests: Ribociclib, Everolimus, Temozolomide (TMZ) Atezolizumab and Pre-Surgical Brain Radiation Therapy for Glioblastoma Multiforme NCT05423210EARLY Phase 11 site📍 Stony Brook Stony Brook University · Tests: Atezolizumab + FSRT radiation Imaging Acetadote Metabolism in Glioblastoma NCT07387666EARLY Phase 11 site📍 Dallas University of Texas Southwestern Medical Center · Tests: Acetadote Pre-Radiation Chemotherapy for Newly Diagnosed High-Grade Glioma. NCT07439172Phase 21 site📍 Camden The Cooper Health System · Tests: Pre-radiation temozolomide. Study of Liposomal Curcumin in Combination With RT and TMZ in Patients With Newly Diagnosed High-Grade Gliomas NCT05768919Phase 1, Phase 22 sites📍 Washington D.C.📍 Baltimore SignPath Pharma, Inc. · Tests: Treatment Period 1, Treatment Period 2, Treatment Period 3, Treatment Period 4a
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