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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

Know your stage or your test results (such as EGFR, HER2 or BRCA)? Match trials to your own profile - nothing you type is saved.

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10 recruiting trials

for Newly Diagnosed MGMT Unmethylated Glioblastoma

Temporally-Modulated Pulsed Radiation Therapy Versus Standard Radiation Therapy for the Treatment of Newly Diagnosed, IDH Wildtype, MGMT-Unmethylated Glioblastoma NCT07452458Phase 354 sites📍 Irvine📍 Los Angeles📍 Orange NRG Oncology · Tests: Biospecimen Collection, Computed Tomography, Magnetic Resonance Imaging, Questionnaire Administration, Radiation Therapy Daily Temozolomide for Elderly Patients With Unmethylated MGMT- Promoter Newly Diagnosed GliOblatoma NCT07476794Phase 21 site📍 Toronto Sunnybrook Health Sciences Centre · Tests: Daily TMZ Ruxolitinib With Radiation and Temozolomide Compared to Radiation and Temozolomide for Newly Diagnosed Glioblastoma NCT06991101Phase 22 sites📍 Miami📍 New York Baptist Health South Florida · Tests: Ruxolitinib, Temozolomide, Radiation Therapy Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIII NCT07326566Phase 235 sites📍 Birmingham📍 Springdale📍 La Jolla Black Diamond Therapeutics, Inc. · Tests: silevertinib in combination with temozolomide, temozolomide (TMZ) Study of Low-Intensity Focused Ultrasound in Combination With Immunotherapy in Newly Diagnosed Unmethylated Glioblastoma NCT07343986Phase 11 site📍 Charlottesville University of Virginia · Tests: anti-EGFR bispecific-armed T cells, Low-Intensity Focused Ultrasound DB107-RRV, DB107-FC, and Radiation Therapy With or Without Temozolomide (TMZ) for High Grade Glioma NCT06504381Phase 1, Phase 25 sites📍 Los Angeles📍 San Diego📍 San Francisco University of California, San Francisco · Tests: DB107-RRV, DB107-FC, Radiation Therapy (RT), Temozolomide, Magnetic Resonance Imaging (MRI) D2C7-IT and 2141-V11 in Newly Diagnosed GBM Patients NCT05734560Phase 1, Phase 21 site📍 Durham Darell Bigner · Tests: D2C7-IT, 2141-V11 A Phase 1/2 Study of the Safety and Tolerability of MT-125 in GBM Patients NCT07185880Phase 1, Phase 23 sites📍 Phoenix📍 Jacksonville📍 Rochester Myosin Therapeutics Inc. · Tests: MT-125 WP1066 and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma NCT05879250Phase 22 sites📍 Chicago📍 Warrenville Northwestern University · Tests: Biospecimen Collection, Magnetic Resonance Imaging, Radiation Therapy, STAT3 Inhibitor WP1066, Surgical Procedure A Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent Glioblastoma NCT03970447Phase 2, Phase 363 sites📍 Birmingham📍 La Jolla📍 Los Angeles Global Coalition for Adaptive Research · Tests: Temozolomide, Lomustine, Regorafenib, Radiation, Paxalisib
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