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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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13 recruiting trials

for Pediatric Recurrent Central Nervous System Tumors

Study of B7-H3-Specific CAR T Cell Locoregional Immunotherapy for Diffuse Intrinsic Pontine Glioma/Diffuse Midline Glioma and Recurrent or Refractory Pediatric Central Nervous System Tumors NCT04185038Phase 11 site📍 Seattle Seattle Children's Hospital · Tests: SCRI-CARB7H3(s); B7H3-specific chimeric antigen receptor (CAR) T cel A Study of RNA-lipid Particle (RNA-LP) Vaccines for Newly Diagnosed Pediatric High-Grade Gliomas (pHGG) and Adult Glioblastoma (GBM) NCT04573140Phase 12 sites📍 Washington D.C.📍 Gainesville University of Florida · Tests: Autologous total tumor mRNA and pp65 full length (fl) lysosomal associated membrane protein (LAMP) mRNA loaded DOTAP li… HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors NCT03911388Phase 13 sites📍 Birmingham📍 St Louis📍 Houston M.D. Anderson Cancer Center · Tests: G207 Neoepitope-based Personalized DNA Vaccine Approach in Pediatric Patients With Recurrent Central Nervous System Tumors NCT03988283Phase 11 site📍 St Louis Washington University School of Medicine · Tests: Personalized neoantigen DNA vaccine, Papivax Biotech TDS-IM v2.0, Peripheral blood draw Virus-Based Gene Therapy (AdV-HSV1-TK and AdV-Flt3L) in Combination With Valacyclovir for the Treatment of Pediatric and Young Adult Patients With Resectable, Recurrent Primary Malignant Brain Tumors NCT06914479Phase 11 site📍 Ann Arbor University of Michigan Rogel Cancer Center · Tests: Ad-hCMV-Flt3L, Ad-hCMV-TK, Biospecimen Collection, Magnetic Resonance Imaging, Survey Administration A Study of Selinexor in People With Wilms Tumors and Other Solid Tumors NCT05985161Phase 216 sites📍 Los Angeles📍 Palo Alto📍 Washington D.C. Memorial Sloan Kettering Cancer Center · Tests: Selinexor A Study of 177Lu-DTPA-Omburtamab in Children and Adolescents With Brain Cancer or Cancer That Has Spread to the Central Nervous System (CNS) NCT07698899Phase 17 sites📍 Basking Ridge📍 Middletown📍 Montvale Memorial Sloan Kettering Cancer Center · Tests: 25 mCi 177Lu- DTPA-omburtamab Immunotherapy for Malignant Pediatric Brain Tumors Employing Adoptive Cellular Therapy (IMPACT) NCT06193759Phase 11 site📍 Washington D.C. Children's National Research Institute · Tests: Multi-tumor antigen specific cytotoxic T lymphocytes (TSA-T) directed against proteogenomically determined personalized… Optimal Precision TherapIes to CustoMISE Care in Childhood and Adolescent Cancer NCT06208657Phase 1, Phase 214 sites📍 Newcastle📍 Sydney📍 Sydney Australian & New Zealand Children's Haematology/Oncology Gr… · Tests: Paxalisib, Opdualag, Irinotecan (drug), Temozolomide (TMZ) B7-H3.CD28Z.CART in CNS Neoplasms NCT07390539Phase 12 sites📍 Boston📍 Boston Robbie Majzner · Tests: B7-H3.CD28Z.CART, Fludarabine, Cyclophosphamide Intratumoral DNX-2401 for High Grade Pediatric Brain Tumors NCT07424092Phase 22 sites📍 Utrecht📍 Pamplona Clinica Universidad de Navarra, Universidad de Navarra · Tests: DNX-2401 PEP-CMV Vaccine Targeting CMV Antigen to Treat Newly Diagnosed Pediatric HGG and DIPG and Recurrent Medulloblastoma NCT05096481Phase 213 sites📍 Aurora📍 Washington D.C.📍 Miami Nationwide Children's Hospital · Tests: PEP-CMV, Temozolomide, Tetanus Diphtheria Vaccine GPC2-CAR T Cell Therapy for Relapsed or Refractory Medulloblastoma in Children and Young Adults NCT07087002Phase 11 site📍 Palo Alto Stanford University · Tests: GPC2-CAR T cells, Fludarabine, Cyclophosphamide
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