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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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18 recruiting trials

for Pediatric Sarcoma, Refractory

Study of CAR T-Cells Targeting the GD2 With IL-15+iCaspase9 for Relapsed/Refractory Neuroblastoma or Relapsed/Refractory Osteosarcoma NCT03721068Phase 12 sites๐Ÿ“ Atlanta๐Ÿ“ Chapel Hill UNC Lineberger Comprehensive Cancer Center ยท Tests: iC9.GD2.CAR.IL-15 T-cells, Cyclophosphamide, Fludarabine Evaluation of Xaluritamig in Adults, Adolescents and Children With Relapsed or Refractory Ewing Sarcoma (EWS) NCT07297979Phase 111 sites๐Ÿ“ Los Angeles๐Ÿ“ Los Angeles๐Ÿ“ Baltimore Amgen ยท Tests: Xaluritamig Phase I Study of Becotatug Vedotin for Safety and Efficacy in EGFR-Positive Pediatric Relapsed/Refractory or Metastatic Solid Tumors NCT07584499Phase 11 site๐Ÿ“ Guangzhou Sun Yat-sen University ยท Tests: Becotatug Vedotin Evaluation of the Efficacy and Safety of Pazopanib in Combination with TGI/CIV for Recurrent or Refractory Rhabdomyosarcoma in Children or Adolescents NCT06816771Phase 21 site๐Ÿ“ Jinan Shandong Cancer Hospital and Institute ยท Tests: pazopanib, TGI chemotherapy, CIV chemotherapy Ex Vivo Drug Sensitivity Testing and Multi-Omics Profiling NCT05857969Phase 11 site๐Ÿ“ Miami Florida International University ยท Tests: Functional Precision Medicine A Multi-Institution Study of TGFฮฒ Imprinted, Ex Vivo Expanded Universal Donor NK Cell Infusions as Adoptive Immunotherapy in Combination With Gemcitabine and Docetaxel in Patients With Relapsed or Refractory Pediatric Bone and Soft Tissue NCT05634369Phase 1, Phase 222 sites๐Ÿ“ South Birmingham๐Ÿ“ Phoenix๐Ÿ“ Little Rock Nationwide Children's Hospital ยท Tests: GEM/DOX + TGFBi expanded NK cells Losartan + Sunitinib in Treatment of Osteosarcoma NCT03900793Phase 14 sites๐Ÿ“ Los Angeles๐Ÿ“ Aurora๐Ÿ“ Aurora University of Colorado, Denver ยท Tests: Losartan, Sunitinib PEEL-224, Vincristine and Temozolomide in Pediatric Solid Tumors NCT06721689Phase 1, Phase 27 sites๐Ÿ“ Los Angeles๐Ÿ“ San Francisco๐Ÿ“ Boston Theodore Laetsch ยท Tests: PEEL-224, Vincristine, Temozolomide (TMZ) A Study of Selinexor in People With Wilms Tumors and Other Solid Tumors NCT05985161Phase 216 sites๐Ÿ“ Los Angeles๐Ÿ“ Palo Alto๐Ÿ“ Washington D.C. Memorial Sloan Kettering Cancer Center ยท Tests: Selinexor Doxorubicin Hydrochloride Liposome Combined With Irinotecan (AI Regimen) Versus VIT Regimen in the Treatment of Relapsed and Refractory Pediatric Rhabdomyosarcoma: a Prospective, Open-label, Randomized Controlled, Multicenter, Phase II Clinical Study NCT05457829Phase 21 site๐Ÿ“ Guangzhou Sun Yat-sen University ยท Tests: Doxorubicin Hydrochloride Liposome+Irinotecan, Temozolomide+Irinotecan+Vincristine Hypofractionated Radiation in Combination With B7-H3-CAR T Cells for Pediatric Patients With Relapsed/Refractory Sarcomas NCT07222735Phase 11 site๐Ÿ“ Memphis St. Jude Children's Research Hospital ยท Tests: Fludarabine, Cyclophosphamide, B7-H3-CAR T Cells, Radiation Therapy Umbilical Cord Blood NK Cell Therapy for High-Risk Pediatric Soft Tissue Sarcoma: Efficacy and Safety Study NCT06848582NA2 sites๐Ÿ“ Guangzhou๐Ÿ“ Dongguan Sun Yat-sen University ยท Tests: umbilical cord blood NK cells Study of Onivyde With Talazoparib or Temozolomide in Children With Recurrent Solid Tumors and Ewing Sarcoma NCT04901702Phase 1, Phase 210 sites๐Ÿ“ Palo Alto๐Ÿ“ Aurora๐Ÿ“ Washington D.C. St. Jude Children's Research Hospital ยท Tests: Onivyde, Talazoparib, Temozolomide Phase 1 Dose-escalating Study of MM-398 (Irinotecan Sucrosofate Liposome Injection) Plus Intravenous Cyclophosphamide in Recurrent or Refractory Pediatric Solid Tumors NCT02013336Phase 15 sites๐Ÿ“ Cincinnati๐Ÿ“ Oklahoma City๐Ÿ“ Dallas South Plains Oncology Consortium ยท Tests: MM-398 (Irinotecan Sucrosofate Liposome Injection) plus cyclophosphamide Alpha/Beta CD19+ Depleted Haploidentical Transplantation + Zometa for Pediatric Hematologic Malignancies and Solid Tumors NCT02508038Phase 11 site๐Ÿ“ Madison University of Wisconsin, Madison ยท Tests: TCRฮฑฮฒ+/CD19+ depleted Haploidentical HSCT, Zoledronate VITAS: Atezolizumab in Combination With Chemotherapy for Pediatric Relapsed/Refractory Solid Tumors NCT04796012Phase 1, Phase 27 sites๐Ÿ“ Chicago๐Ÿ“ Boston๐Ÿ“ Cincinnati University of Texas Southwestern Medical Center ยท Tests: Atezolizumab, Vincristine, Irinotecan, Temozolomide Alpha/Beta T and B Cell Depletion With Zoledronic Acid for Solid Tumors NCT06625190Phase 1, Phase 21 site๐Ÿ“ Gainesville University of Florida ยท Tests: Miltenyi CliniMACS Prodigy ยฎ system, Zoledronic acid Study of Lurbinectedin Monotherapy in Pediatric and Young Adult Participants With Relapsed/Refractory Ewing Sarcoma NCT05734066Phase 1, Phase 215 sites๐Ÿ“ Los Angeles๐Ÿ“ Palo Alto๐Ÿ“ Washington D.C. Jazz Pharmaceuticals ยท Tests: Lurbinectedin
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