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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Pirtobrutinib

Pirtobrutinib and Mosunetuzumab for the Treatment of Relapsed/Refractory Grades 1-3A Follicular Lymphoma, PROMOTE-FL Trial NCT06948786Phase 21 site๐Ÿ“ Seattle University of Washington ยท Tests: Pirtobrutinib, Mosunetuzumab, Biospecimen Collection, Biopsy Procedure, Computed Tomography Implanted Loop Recorders for Detection and Management of Arrhythmia With Bruton Tyrosine Kinase Inhibitors NCT05643235NA1 site๐Ÿ“ New Hyde Park Northwell Health ยท Tests: Medtronic LINQ-2 Insertable Cardiac Monitor (ILR) A Study Evaluating the Efficacy and Safety of Pirtobrutinib in Participants With Relapsed or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma NCT06588478Phase 2131 sites๐Ÿ“ Chandler๐Ÿ“ Duarte๐Ÿ“ Irvine Loxo Oncology, Inc. ยท Tests: Pirtobrutinib Pirtobrutinib for the Treatment of Elderly Patients With Chronic Lymphocytic Leukemia NCT07685717Phase 21 site๐Ÿ“ Columbus Jennifer Woyach ยท Tests: Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy, Computed Tomography, Electronic Health Record Review Time-limited Triplet Combination of Pirtobrutinib, Venetoclax, and Obinutuzumab for Patients With Treatment-naรฏve Chronic Lymphocytic Leukemia (CLL) or Richter Transformation (RT) NCT05536349Phase 21 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Pirtobrutinib, Obinutuzumab, Venetoclax, Valacyclovir, Allopurinol Immune Profiling of CLL/SLL Treated With First-Line Pirtobrutinib NCT07428707EARLY Phase 11 site๐Ÿ“ Bethesda National Heart, Lung, and Blood Institute (NHLBI) ยท Tests: Pirtobrutinib R-PMDT Regimen in Newly Diagnosed PCNSL NCT07604987Phase 21 site๐Ÿ“ Tianjin Zou Dehui ยท Tests: R-PMDT A Master Protocol to Evaluate the Long-Term Safety of (LY3527727) Pirtobrutinib NCT06876649Phase 438 sites๐Ÿ“ Jacksonville๐Ÿ“ Miami๐Ÿ“ Sarasota Eli Lilly and Company ยท Tests: Pirtobrutinib Phase II Study of Pirtobrutinib, Rituximab (PR) in Previously Untreated Low and Intermediate Risk MCL (Mantle Cell Lymphoma) Patients NCT06263491Phase 21 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Rituximab, Pirtobrutinib A Study to Evaluate the Safety and Efficacy of Tacabrutideg (BGB-16673) Compared to Pirtobrutinib in Adults With Relapsed/Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma NCT06973187Phase 3217 sites๐Ÿ“ Birmingham๐Ÿ“ Phoenix๐Ÿ“ Irvine BeOne Medicines ยท Tests: Tacabrutideg, Pirtobrutinib Phase II Study of Pirtobrutinib With Venetoclax In Relapsed-Refractory MCL (Mantle Cell Lymphoma) Patients NCT05529069Phase 21 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Pirtobrutinib, Venetoclax Thiotepa in Combination With Pirtobrutinib (a BTK Inhibitor) and Sintilimab (a PD-1 Inhibitor) for Frail or Relapsed/Refractory Primary or Secondary Central Nervous System Lymphoma NCT07416890Phase 21 site๐Ÿ“ Hangzhou Zhejiang Cancer Hospital ยท Tests: Thiotepa, Pirtobrutinib , Sintilimab(TPS) A Study of Pirtobrutinib (LOXO-305) Versus Ibrutinib in Participants With Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL) NCT05254743Phase 3143 sites๐Ÿ“ Anaheim๐Ÿ“ Cerritos๐Ÿ“ Palo Alto Loxo Oncology, Inc. ยท Tests: Pirtobrutinib, Ibrutinib Study of NX-5948 Versus Pirtobrutinib in R/R CLL/SLL NCT07516093Phase 36 sites๐Ÿ“ Macon๐Ÿ“ Fort Wayne๐Ÿ“ Indianapolis Nurix Therapeutics, Inc. ยท Tests: NX-5948, Pirtobrutinib A Phase 2 Trial of GlOfitamab anD pIrtobrutinib in Mantle Cell Lymphoma Patients With Prior BTK Inhibitor Exposure. NCT05833763Phase 22 sites๐Ÿ“ Parkville๐Ÿ“ Nedlands Australasian Leukaemia and Lymphoma Group ยท Tests: Glofitamab, Pirtobrutinib, Obinutuzumab, Tocilizumab Phase 2 Study of Glofitamab Monotherapy & With Polatuzumab Vedotin, Pirtobrutinib, or Atezolizumab in Richter's Transformation NCT06043674Phase 25 sites๐Ÿ“ Atlanta๐Ÿ“ Boston๐Ÿ“ Boston Christine Ryan ยท Tests: Glofitamab, Obinutuzumab, Polatuzumab Vedotin, Atezolizumab, Tocilizumab A Study of Pirtobrutinib (LY3527727) in Participants With Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma NCT07218341Phase 450 sites๐Ÿ“ Mobile๐Ÿ“ Tucson๐Ÿ“ Jacksonville Eli Lilly and Company ยท Tests: Pirtobrutinib, Idelalisib Pirtobrutinib (LOXO-305) and Venetoclax for the Treatment of Patients With CLL or SLL Resistant to Covalent BTKi NCT06466122Phase 21 site๐Ÿ“ Columbus Kerry Rogers ยท Tests: Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy, Computed Tomography, Pirtobrutinib LV20.19 CAR T-Cells in Combination With Pirtobrutinib for Relapsed, Refractory B-cell Malignancies NCT05990465Phase 11 site๐Ÿ“ Milwaukee Medical College of Wisconsin ยท Tests: Pirtobrutinib, LV20.19 CAR T cells Clinical Trial to Evaluate the Efficacy and Safety of Pirtobrutinib With Rituximab in Patients With Mantle Cell Lymphoma NCT07285590Phase 216 sites๐Ÿ“ Lisbon๐Ÿ“ Lisbon๐Ÿ“ Badalona Grupo Espaรฑol de Linfomas y Transplante Autรณlogo de Mรฉdula โ€ฆ ยท Tests: Pirtobrutinib and rituximab Adding Pirtobrutinib to the Usual Treatment for People With Newly Diagnosed Richter Transformation, The PIRAMID Trial NCT07220187Phase 362 sites๐Ÿ“ Irvine๐Ÿ“ Laguna Hills๐Ÿ“ Orange SWOG Cancer Research Network ยท Tests: Biospecimen Collection, Computed Tomography, Cyclophosphamide, Doxorubicin Hydrochloride, Echocardiography Test A Study of Pirtobrutinib, Venetoclax, and Rituximab in People With Waldenstrรถm's Macroglobulinemia (WM)/Lymphoplasmacytic Lymphoma (LPL) NCT07231952Phase 29 sites๐Ÿ“ Boston๐Ÿ“ Boston๐Ÿ“ Basking Ridge Memorial Sloan Kettering Cancer Center ยท Tests: Pirtobrutinib, Venetoclax, Rituximab A Study of (LY3527727) Pirtobrutinib in Participants With Previously Treated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma or Non-Hodgkin Lymphoma NCT06876662Phase 436 sites๐Ÿ“ Miami๐Ÿ“ Sarasota๐Ÿ“ Atlanta Eli Lilly and Company ยท Tests: Pirtobrutinib Glofitamab With Pirtobrutinib for Relapsed or Refractory Mantle Cell Lymphoma NCT06252675Phase 24 sites๐Ÿ“ Davis๐Ÿ“ Los Angeles๐Ÿ“ San Diego University of California, San Francisco ยท Tests: Obinutuzumab, Glofitamab, Pirtobrutinib, Tumor Imaging, Biospecimen Collection A Study of Pirtobrutinib in Participants With Immune Thrombocytopenia NCT06721013Phase 1, Phase 243 sites๐Ÿ“ Los Angeles๐Ÿ“ Palo Alto๐Ÿ“ Washington D.C. Eli Lilly and Company ยท Tests: Pirtobrutinib, Placebo ROCKET-CLL Global Phase 3 Study: Rocbrutinib vs Pirtobrutinib in cBTKi-Pretreated R/R CLL/SLL NCT07342478Phase 36 sites๐Ÿ“ Skokie๐Ÿ“ Bethesda๐Ÿ“ Las Vegas Newave Pharmaceutical Inc ยท Tests: Rocbrutinib, Pirtobrutinib Pirtobrutinib, Lisaftoclax, and Rituximab in the Treatment of R/R DLBCL NCT07255963Phase 21 site๐Ÿ“ Suzhou The First Affiliated Hospital of Soochow University ยท Tests: Pirtobrutinib, Lisaftoclax, Rituximab A Multicenter, Prospective Clinical Trial With a Concurrent Control Evaluating Methotrexate Combined With Rituximab,Sintilimab and Pirtobrutinib vs. Investigator-Selected Standard of Care in Treatment-Naive PCNSL NCT07350850Phase 24 sites๐Ÿ“ Xiamen๐Ÿ“ Wuhan๐Ÿ“ Changchun Tongji Hospital ยท Tests: Pirtobrutinib, Sintilimab, Rituximab, Methotrexate, Standard of Care (Investigator Selected) Phase 2 Open Label Randomized Study of Pirtobrutinib and Brexucabtagene Autoleucel in R/R MCL NCT06553872Phase 23 sites๐Ÿ“ Stanford๐Ÿ“ Miami๐Ÿ“ Tampa H. Lee Moffitt Cancer Center and Research Institute ยท Tests: Pirtobrutinib, Brexucabtagene Autoleucel Pirtobrutinib in Combination With Rituximab in Adults With Untreated Marginal Zone Lymphoma (PIONEER-MZL) NCT06390956Phase 22 sites๐Ÿ“ St Louis๐Ÿ“ Salt Lake City University of Utah ยท Tests: Pirtobrutinib, Rituximab
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