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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

Know your stage or your test results (such as EGFR, HER2 or BRCA)? Match trials to your own profile - nothing you type is saved.

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30 recruiting trials

for Primary Immunodeficiency Diseases

Immune Cell Therapy (CAR-T) for the Treatment of Patients With HIV and B-Cell Non-Hodgkin Lymphoma NCT05077527Phase 17 sites📍 Duarte📍 Chicago📍 New York AIDS Malignancy Consortium · Tests: Axicabtagene Ciloleucel, Cyclophosphamide, Fludarabine The Experience of Screening for SCID NCT05651113n/a1 site📍 London King's College London · Tests: SCID Screening Treatment of Refractory BK Infections With Related Donor BK Specific Cytotoxic T-cells (CTLs) NCT04197596Phase 1, Phase 27 sites📍 San Francisco📍 Baltimore📍 St Louis New York Medical College · Tests: BK CTL Safety and Efficacy of Mutation-targeted Precision Genetic Therapy for Ataxia-Telangiectasia (A-T) NCT07215416Phase 1, Phase 21 site📍 Boston Timothy Yu · Tests: Antisense oligonucleotide targeting the ATM gene Studies of Disorders With Increased Susceptibility to Fungal Infections NCT01222741n/a1 site📍 Bethesda National Institute of Allergy and Infectious Diseases (NIAI… Data Collection Study of Patients With Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT With RIC NCT04528355n/a1 site📍 Pittsburgh Paul Szabolcs · Tests: data collection Targeting Real World Usage In Stroke Treatment NCT07474935n/a13 sites📍 Brest📍 Paris📍 Erfurt Phenox GmbH · Tests: Aneurysm Treatment with a Neurovascular Flow Diverter, Dissection Treatment with a Neurovascular Flow Diverter, Perfora… Leukapheresis Procedures to Obtain Plasma and Lymphocytes for Research Studies on Antiretroviral Naive HIV-1 Research Participants NCT00039689n/a1 site📍 Bethesda National Institute of Allergy and Infectious Diseases (NIAI… Exercise Intervention and Immunodeficiency NCT07698197NA2 sites📍 Milford📍 North Haven Yale University · Tests: App-based exercise intervention Pathogenic Study of Adult Immune Enteropathies NCT04280510n/a4 sites📍 Créteil📍 Le Kremlin-Bicêtre📍 Paris Institut National de la Santé Et de la Recherche Médicale, … · Tests: Blood sample collection; gastrointestinal biopsy An Phase Ib/II Clinical Trial of TCC1727 Combination Therapy in Advanced Solid Tumors NCT07371663Phase 1, Phase 23 sites📍 Beijing📍 Zhengzhou📍 Hangzhou Beijing Tide Pharmaceutical Co., Ltd · Tests: TCC1727 tablet 90mg, TCC1727 tablet 120mg, TCC1727 tablet 160mg, benmelstobart Injection Screening Protocol for Genetic Diseases of Lymphocyte Homeostasis and Programmed Cell Death NCT00246857n/a8 sites📍 Bethesda📍 Ann Arbor📍 Ankara National Institute of Allergy and Infectious Diseases (NIAI… Metabolic Profiling of Immune Responses in Immune-mediated Diseases NCT04864886n/a1 site📍 Bethesda National Institute of Allergy and Infectious Diseases (NIAI… Prevalence, Incidence and Risk Signature of Chronic Kidney Disease in Sub-Saharan Africa NCT05881447n/a1 site📍 Bagamoyo Swiss Tropical & Public Health Institute Ex Vivo Evaluation of JAK-inhibitor and Gene Therapeutical Approach in JAK-STAT Related Disorders NCT07261891NA1 site📍 Leuven prof. dr. Rik Schrijvers · Tests: blood sampling Shwachman-Diamond Syndrome Global Patient Survey and Partnering Platform NCT06999954n/a1 site📍 Woburn Shwachman-Diamond Syndrome Alliance Inc Development of IPS from Donated Somatic Cells of Patients with Neurological Diseases NCT00874783n/a1 site📍 Jerusalem Hadassah Medical Organization A Randomised Placebo Controlled Trial of ART Plus Dual Long-acting HIV-specific Broadly Neutralising Antibodies (bNAbs). NCT04319367Phase 212 sites📍 Aarhus📍 Brighton📍 Edinburgh Imperial College London · Tests: Investigational Medicinal Product Oral Deucrictibant for Prophylactic and Acute Treatment in Hereditary Angioedema Patients NCT07046806Phase 1, Phase 21 site📍 Wheaton Institute for Asthma and Allergy · Tests: Deucrictibant XR tablet, Placebo comparator to XR tablet, Deucrictibant 20 mg capsule, Placebo comparator to 20 mg caps… Phase I/II Trial of Lentiviral Gene Transfer for SCID-X1 With Low Dose Targeted Busulfan Conditioning NCT03311503Phase 1, Phase 24 sites📍 Los Angeles📍 Atlanta📍 Boston David Williams · Tests: autologous CD34+ cell transduced with G2SCID vector Allogeneic Hematopoietic Stem Cell Transplant for Patients With Inborn Errors of Immunity NCT04339777Phase 21 site📍 Bethesda National Cancer Institute (NCI) · Tests: Busulfan test dose, Fludarabine, Busulfan, Alemtuzumab, Total body Irradiation Improving Deceased-Donor Kidney Transplant Outcomes Via a Single Intragraft Injection of C1 Esterase Inhibitor (IMPROVE TRIAL) NCT06919003Phase 24 sites📍 Los Angeles📍 Chicago📍 Kansas City National Institute of Allergy and Infectious Diseases (NIAI… · Tests: Berinert, Placebo for Berinert Safety and Effectiveness of Sebetralstat (KVD900) for Short-Term Prophylaxis Before Procedures in People With Hereditary Angioedema (KONTROL) NCT07654829Phase 41 site📍 Colorado Springs KalVista Pharmaceuticals, Ltd. · Tests: KVD900 600 mg Detection and Characterization of Infections and Infection Susceptibility NCT00404560n/a1 site📍 Bethesda National Institute of Allergy and Infectious Diseases (NIAI… A Natural History Study Seeks to Understand the Clinical, Genomic, Pharmacological, Laboratory, and Dietary Determinates of Pyrimidine and Purine Metabolism Disorders NCT06092346n/a1 site📍 Bethesda National Human Genome Research Institute (NHGRI) Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford NCT01793168n/a2 sites📍 Sioux Falls📍 Sydney Sanford Health COVID-19 in PID Survey NCT04459689n/a1 site📍 Paris Imagine Institute Angioedema Biomarker Research Study NCT06210698n/a1 site📍 Wheaton Foundation For Rare Disease Research · Tests: Venipuncture Lentiviral Gene Transfer for Treatment of Children Older Than Two Years of Age With X-Linked Severe Combined Immunodeficiency (XSCID) NCT01306019Phase 1, Phase 21 site📍 Bethesda National Institute of Allergy and Infectious Diseases (NIAI… · Tests: Ex vivo culture and transduction of the patient's autologous CD34+ HSC with lentivirus vector VSV-G pseudotyped CL… Characterization of Acute and Recent HIV-1 Infections in Zurich. NCT00537966n/a1 site📍 Zurich University of Zurich
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