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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Primary Mediastinal Diffuse Large B-cell Lymphoma

SynKIR-310 for Relapsed/Refractory B-NHL NCT06544265Phase 15 sites📍 Denver📍 Atlanta📍 Fairway Verismo Therapeutics · Tests: SynKIR-310 Immune Cell Therapy (CAR-T) for the Treatment of Patients With HIV and B-Cell Non-Hodgkin Lymphoma NCT05077527Phase 17 sites📍 Duarte📍 Chicago📍 New York AIDS Malignancy Consortium · Tests: Axicabtagene Ciloleucel, Cyclophosphamide, Fludarabine Odronextamab for Relapsed and Refractory Large B-cell Lymphomas Before CAR-T NCT06784726Phase 21 site📍 Seattle University of Washington · Tests: Odronextamab, Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy, Chimeric Antigen Receptor T-Cell Ther… The OPAL Study: AVM0703 for Treatment of Lymphoid Malignancies NCT04329728Phase 1, Phase 211 sites📍 Duarte📍 Los Angeles📍 Los Angeles AVM Biotechnology Inc · Tests: AVM0703 CD79b-19 CAR T Cells in Non-Hodgkin Lymphoma NCT06026319Phase 11 site📍 Boston Marcela V. Maus, M.D.,Ph.D. · Tests: CD79b-19 CAR T cells, Cyclophosphamide, Fludarabine Epcoritamab Plus Ibrutinib for the Treatment of Relapsed or Refractory Aggressive B-Cell Non-Hodgkin Lymphoma NCT06536049Phase 1, Phase 23 sites📍 Minneapolis📍 Columbus📍 Richmond Yazeed Sawalha · Tests: Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy, Computed Tomography, Epcoritamab Golcadomide and Rituximab as Bridging Therapy for Relapsed or Refractory Aggressive B-cell Non-Hodgkin Lymphoma Before CAR T-cell Therapy NCT06834373Phase 27 sites📍 Scottsdale📍 Jacksonville📍 Albert Lea Mayo Clinic · Tests: Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy, Chimeric Antigen Receptor T-Cell Therapy, Computed … B-cell Mature Non-Hodgkin's Lymphoma Treatment Protocol in Children and Adolescents 2021 NCT05518383Phase 41 site📍 Moscow Federal Research Institute of Pediatric Hematology, Oncolog… · Tests: Cyclophosphamide, Cytarabine, Dexamethasone, Etoposide, Ifosfamide, Methotrexate, Cyclophosphamide, Cytarabine, Dexamet… A Phase 1/2 Study of UB-VV400 With Rapamycin in Relapsed/Refractory B-cell Malignancies NCT07735533Phase 1, Phase 21 site📍 Nashville Umoja Biopharma · Tests: UB-VV400, Rapamycin (sirolimus) Epcoritamab Compared to Observation for Treating B-cell Lymphoma Patients Not in Complete Remission After CD19-directed CAR-T Therapy NCT06238648Phase 26 sites📍 Rochester📍 St Louis📍 Hackensack Academic and Community Cancer Research United · Tests: Biopsy, Biospecimen Collection, Computed Tomography, Epcoritamab, Magnetic Resonance Imaging Sintilimab Plus Rituximab Followed by R-CHOP Regimen in Untreated PMBL NCT06742502Phase 22 sites📍 Fuzhou📍 Guangzhou Sun Yat-sen University · Tests: Sintlimab+Rituximab follwed by R-CHOP(Cyclophosphamide, doxorubicin, vincristine, prednisone) Sequential Treatment of CD19 CARNK and 7x19 CAR-T in R/R B Cell Lymphoma NCT06464861Phase 11 site📍 Hangzhou Second Affiliated Hospital, Zhejiang University, School of … · Tests: CD19-CAR-NK/T Testing Drug Treatments After CAR T-cell Therapy in Patients With Relapsed/Refractory Diffuse Large B-cell Lymphoma NCT05633615Phase 295 sites📍 Tucson📍 Tucson📍 Fayetteville SWOG Cancer Research Network · Tests: Axicabtagene Ciloleucel, Biospecimen Collection, Computed Tomography, Cyclophosphamide, Fludarabine Rituximab (Rtx) + Tafasitamab in Combination With Allogeneic NK Cells for Treatment of Relapsed/Refractory (r/r) B-cell Non-Hodgkin Lymphoma (NHL) NCT07225439Phase 12 sites📍 Cleveland📍 Cleveland Paolo Caimi, MD · Tests: Allogeneic NK cells, Rituximab, Tafasitamab, Interleukin-2, Fludarabine/cyclophosphamide Study of Safety and Efficacy of TC011 in the Relapsed/Refractory Large B Cell Non-Hodgkin Lymphoma Patients NCT07473167Phase 1, Phase 21 site📍 Seoul TICAROS Co., Ltd. · Tests: TC011 Bio-CAR-T BS Study NCT05366569n/a1 site📍 Brescia Azienda Socio Sanitaria Territoriale degli Spedali Civili d… Lifestyles Implemented-Survivorship Care Plan In Lymphoma Survivors NCT05934084NA40 sites📍 Ancona📍 Aviano📍 Bari Fondazione Italiana Linfomi - ETS · Tests: Lifestyles Implemented-Survivorship Care Plan (LS-SCP) Immunotherapy in Lymphoma NCT06796517n/a2 sites📍 Seoul📍 Seoul Sung-Soo Park · Tests: CAR-T Therapy, Bispecific antibody, Antibody-Drug Conjugate, Monoclonal antibody, Proteasome Inhibitor CAR-20/19-T Cells in Patients With Relapsed Refractory B Cell Malignancies NCT04186520Phase 1, Phase 21 site📍 Milwaukee Medical College of Wisconsin · Tests: 8/12-Day Production of Car-T Cells, 8/12-Day Production of Cryopreserved Car-T Cells, 12-Day Production of Car-T Cells Gene Therapy for CD19-Positive Hematologic Malignancies (SENTRY-CD19) NCT06533579Phase 1, Phase 211 sites📍 Duarte📍 Los Angeles📍 Denver Vironexis Biotherapeutics Inc. · Tests: Dose Level 1, VNX-101, Dose Level 2, VNX-101, Dose Level 3, VNX-101, Dose Level 4, VNX-101 CC-99282 + Rituximab Early Post CART for Non-Hodgkin's Lymphoma NCT06209619Phase 11 site📍 Columbus Nathan Denlinger · Tests: Biopsy, Biospecimen Collection, Computed Tomography, Golcadomide, Positron Emission Tomography Pembro Plus CAR T-cell Therapy in R/R in PMBCL NCT05934448Phase 22 sites📍 Boston📍 New York Jennifer Crombie, MD · Tests: Pembrolizumab, Lymphodepletion Chemotherapy, Chimeric Antigen Receptor (CAR) Therapy Infusion, Leukapheresis Epcoritamab, Rituximab, Gemcitabine and Oxaliplatin (R-GemOx) as Salvage Therapy Before Autologous Stem Cell Transplant for the Treatment of Relapsed/Refractory Diffuse Large B-Cell Lymphoma NCT07365306Phase 23 sites📍 Duarte📍 Newnan📍 Zion City of Hope Medical Center · Tests: Autologous Hematopoietic Stem Cell Transplantation, Biopsy Procedure, Biospecimen Collection, Bone Marrow Aspiration, B… Obinutuzumab and ICE Chemotherapy in Refractory/Recurrent CD20+ Mature NHL NCT02393157Phase 21 site📍 Valhalla New York Medical College · Tests: Obinutuzumab, Liposomal ARA-C, Ifosfamide, Carboplatin, Etoposide Sample Collection for Ongoing Research and Product Evaluation Study - Non-Hodgkin Lymphoma (SCORE-NHL) NCT07750886n/a1 site📍 Austin Natera, Inc. Golcadomide Post-CAR T-cell in R/R Aggressive Large B-cell Lymphoma Patients With High Risk of Relapse NCT06271057Phase 213 sites📍 Créteil📍 Dijon📍 La Tronche The Lymphoma Academic Research Organisation · Tests: golcadomide A Phase Ib/II Exploratory Clinical Trial of Memory-Enhanced 7×19-THEMIS CAR-T Cell Therapy for Relapsed/Refractory Large B-Cell Lymphoma NCT07788118Phase 1, Phase 21 site📍 Hangzhou Second Affiliated Hospital, Zhejiang University, School of … · Tests: 7×19-THEMIS CAR-T cells Epcoritamab With Dose Adjusted Etoposide, Cyclophosphamide, Vincristine, Doxorubicin, Prednisone and Rituximab (EPOCH-R) for the Treatment of Aggressive B-Cell Non-Hodgkin Lymphoma NCT07097363Phase 21 site📍 Seattle University of Washington · Tests: Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy, Computed Tomography, Cyclophosphamide Italian Observational Study on CAR-T Therapy for Lymphoma NCT06339255n/a1 site📍 Milan Paolo Corradini Long-term Follow-up Study of Lentiviral-based Gene-edited Immune Cell Therapy NCT05377307n/a5 sites📍 Kaohsiung📍 Taipei📍 Taipei Pell Bio-Med Technology Co., Ltd. · Tests: Pell's lentiviral-based gene-edited immune cell therapy
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