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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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11 recruiting trials

for Primary T-cell Immunodeficiency Disorders

Immune Cell Therapy (CAR-T) for the Treatment of Patients With HIV and B-Cell Non-Hodgkin Lymphoma NCT05077527Phase 17 sites๐Ÿ“ Duarte๐Ÿ“ Chicago๐Ÿ“ New York AIDS Malignancy Consortium ยท Tests: Axicabtagene Ciloleucel, Cyclophosphamide, Fludarabine Treatment of Refractory BK Infections With Related Donor BK Specific Cytotoxic T-cells (CTLs) NCT04197596Phase 1, Phase 27 sites๐Ÿ“ San Francisco๐Ÿ“ Baltimore๐Ÿ“ St Louis New York Medical College ยท Tests: BK CTL Screening Protocol for Genetic Diseases of Lymphocyte Homeostasis and Programmed Cell Death NCT00246857n/a8 sites๐Ÿ“ Bethesda๐Ÿ“ Ann Arbor๐Ÿ“ Ankara National Institute of Allergy and Infectious Diseases (NIAIโ€ฆ Allogeneic Hematopoietic Stem Cell Transplant for Patients With Inborn Errors of Immunity NCT04339777Phase 21 site๐Ÿ“ Bethesda National Cancer Institute (NCI) ยท Tests: Busulfan test dose, Fludarabine, Busulfan, Alemtuzumab, Total body Irradiation Lentiviral Gene Transfer for Treatment of Children Older Than Two Years of Age With X-Linked Severe Combined Immunodeficiency (XSCID) NCT01306019Phase 1, Phase 21 site๐Ÿ“ Bethesda National Institute of Allergy and Infectious Diseases (NIAIโ€ฆ ยท Tests: Ex vivo culture and transduction of the patient's autologous CD34+ HSC with lentivirus vector VSV-G pseudotyped CLโ€ฆ Virus Specific Cytotoxic T-Lymphocytes (CTLs) for Refractory Cytomegalovirus (CMV) NCT03266640Phase 29 sites๐Ÿ“ Los Angeles๐Ÿ“ San Francisco๐Ÿ“ Indianapolis New York Medical College ยท Tests: viral specific cytotoxic t-lymphocytes Phase 1/2: CD45RA Depleted Stem Cell Addback to Prevent Viral or Fungal Infections Post TCRab/CD19 Depleted HSCT NCT06839456Phase 1, Phase 21 site๐Ÿ“ Philadelphia Children's Hospital of Philadelphia ยท Tests: Phase 1 Dose Level 1, Phase 1 Dose Level 2, Phase 1 Dose Level 3, Phase 2 Maximum Tolerated Dose determined in Phase 1,โ€ฆ Pilot Trial of Allogeneic Blood or Marrow Transplantation for Primary Immunodeficiencies NCT02579967Phase 22 sites๐Ÿ“ Bethesda๐Ÿ“ Minneapolis National Cancer Institute (NCI) ยท Tests: Immunosuppression Only Conditioning -Closed with amendment L, Reduced Intensity Conditioning, Myeloablative Conditioninโ€ฆ Adoptive T Lymphocyte Administration for Chronic Norovirus Treatment in Immunocompromised Hosts NCT04691622Phase 13 sites๐Ÿ“ Washington D.C.๐Ÿ“ Baltimore๐Ÿ“ Bethesda Children's National Research Institute ยท Tests: Norovirus -specific T-cell (NST) therapy The Mechanistic Biology of Primary Immunodeficiency Disorders NCT03394053n/a2 sites๐Ÿ“ Washington D.C.๐Ÿ“ Bethesda National Institute of Allergy and Infectious Diseases (NIAIโ€ฆ TCR Alpha Beta T-cell Depleted Haploidentical HCT in the Treatment of Primary Immunodeficiency and Inherited Metabolic Disorders in Children NCT04414046Phase 21 site๐Ÿ“ St. Petersburg Johns Hopkins All Children's Hospital ยท Tests: Haploidentical Hematopoietic Cell Transplantation
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