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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Recurrent Chronic Lymphocytic Leukemia

Q702 for the Treatment of Patients With Hematologic Malignancies NCT06712810Phase 12 sites๐Ÿ“ Scottsdale๐Ÿ“ Rochester Mayo Clinic ยท Tests: Axl/Mer/CSF1R Inhibitor Q702, Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy, Computed Tomography Blinatumomab, Methotrexate, Cytarabine, and Ponatinib in Treating Patients With Philadelphia Chromosome-Positive, or BCR-ABL Positive, or Relapsed/Refractory, Acute Lymphoblastic Leukemia NCT03263572Phase 21 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Blinatumomab, Cytarabine, Methotrexate, Ponatinib Allo HSCT Using RIC and PTCy for Hematological Diseases NCT05805605Phase 21 site๐Ÿ“ Minneapolis Masonic Cancer Center, University of Minnesota ยท Tests: Peripheral Blood Stem Cell Transplant, Allopurinol 300 MG, Fludarabine, Cyclophosphamide, Bone Marrow Cell Transplant Roginolisib (IOA-244) With Venetoclax and Rituximab for Refractory/Relapsed Chronic Lymphocytic Leukemia (CLL) NCT06644183Phase 1, Phase 21 site๐Ÿ“ Boston Jennifer R. Brown, MD, PhD ยท Tests: Roginolisib, Venetoclax, Rituximab Safety and Efficacy of Ponatinib for Treatment of Pediatric Recurrent or Refractory Leukemias, Lymphomas or Solid Tumors NCT03934372Phase 1, Phase 223 sites๐Ÿ“ Ghent๐Ÿ“ Paris๐Ÿ“ Paris Incyte Biosciences International Sร rl ยท Tests: Ponatinib HA-1 T TCR T Cell Immunotherapy for the Treatment of Patients With Relapsed or Refractory Acute Leukemia After Donor Stem Cell Transplant NCT03326921Phase 11 site๐Ÿ“ Seattle Fred Hutchinson Cancer Center ยท Tests: CD8+ and CD4+ Donor Memory T-cells-expressing HA1-Specific TCR, Bone Marrow Aspiration, Biospecimen Collection Study to Assess Change in Disease Activity and Adverse Events of Oral Venetoclax With Intravenous (IV) Obinutuzumab in Adult Participants With Recurring Chronic Lymphocytic Leukemia (CLL) NCT04895436Phase 258 sites๐Ÿ“ La Jolla๐Ÿ“ Atlanta๐Ÿ“ Des Moines AbbVie ยท Tests: Venetoclax, Obinutuzumab CD19/CD22 Bicistronic Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults With Recurrent or Refractory B Cell Malignancies NCT05442515Phase 1, Phase 21 site๐Ÿ“ Bethesda National Cancer Institute (NCI) ยท Tests: CD19/CD22-CAR-transduced T cells, cyclophosphamide, fludarabine Sonrotoclax, Rituximab, and Zanubrutinib in Treating Participants With Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, and Mantle Cell Lymphoma NCT06839053Phase 21 site๐Ÿ“ Seattle Fred Hutchinson Cancer Center ยท Tests: Biospecimen Collection, Bone Marrow Biopsy, Computed Tomography, Gastrointestinal Endoscopy, Rituximab Zanubrutinib in Combination With Sonrotoclax for the Treatment of Underrepresented Ethnic and Racial Minorities With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma NCT06859008Phase 11 site๐Ÿ“ Duarte City of Hope Medical Center ยท Tests: Biopsy, Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy, Computed Tomography A Study of APG-3288 in Relapsed/Refractory Blood Cancers NCT07424833Phase 16 sites๐Ÿ“ Los Angeles๐Ÿ“ Jacksonville๐Ÿ“ Grand Rapids Ascentage Pharma Group Inc. ยท Tests: APG-3288 Personalized NK Cell Therapy in CBT NCT02727803Phase 21 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Allogeneic Natural Killer Cell Line NK-92, Anti-Thymocyte Globulin, Busulfan, Clofarabine, Cyclophosphamide Ex Vivo Drug Sensitivity Testing and Multi-Omics Profiling NCT05857969Phase 11 site๐Ÿ“ Miami Florida International University ยท Tests: Functional Precision Medicine MAVRiC Studies 2L Treatment With AV in Patients With CLL/SLL Who Have Relapsed After a Course of BTKi + BCL2i Combination, With or Without Obinutuzumab NCT07024706Phase 247 sites๐Ÿ“ Boston๐Ÿ“ Charlotte๐Ÿ“ Charlotte AstraZeneca ยท Tests: Acalabrutinib, Venetoclax Acalabrutinib in Combination With Venetoclax for the Treatment of Refractory or Recurrent Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma, The AVENUE-2 Trial NCT04941716Phase 21 site๐Ÿ“ Seattle Fred Hutchinson Cancer Center ยท Tests: Acalabrutinib, Venetoclax, Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy Study of TBI-2001(Autologous CD19 Specific Chimeric Antigen Receptor (CAR) Gene-transduced T Lymphocytes) for Relapsed or Refractory CD19+ B-cell Lymphoma, CLL/SLL NCT05963217Phase 11 site๐Ÿ“ Toronto University Health Network, Toronto ยท Tests: TBI-2001, Cyclophosphamide, Fludarabine 211^At-BC8-B10 Before Donor Stem Cell Transplant in Treating Patients With High-Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Myelodysplastic Syndrome, or Mixed-Phenotype Acute Leukemia NCT03128034Phase 1, Phase 21 site๐Ÿ“ Seattle Fred Hutchinson Cancer Center ยท Tests: Cyclosporine, Fludarabine Phosphate, Mycophenolate Mofetil, Peripheral Blood Stem Cell Transplantation, Pretargeted Radโ€ฆ Zanubrutinib in Combination With Odronextamab for the Treatment of Patients With Richter's Transformation NCT06735664Phase 11 site๐Ÿ“ Duarte City of Hope Medical Center ยท Tests: Biopsy, Biospecimen Collection, Bone Marrow Biopsy, Computed Tomography, Echocardiography Clinical Trial Using CAR- T Cells for Treatment of Patients With Refractory or Relapsed CD19-positive B Lymphoid Malignancies NCT05705570Phase 11 site๐Ÿ“ Sรฃo Paulo Nelson Hamerschlak ยท Tests: Cyclophosphamide, Fludarabine, Chimeric antigen receptor T cells to be implemented in a "3 + 3" design on dayโ€ฆ Activated T-Cells Expressing 2nd or 3rd Generation CD19-Specific CAR, Advanced B-Cell NHL, ALL, and CLL (SAGAN) NCT01853631Phase 12 sites๐Ÿ“ Houston๐Ÿ“ Houston Baylor College of Medicine ยท Tests: Dose Escalation Phase:CD19.CAR/28 and CD19.CAR/28137 T cells, Expansion Phase: CD19.CAR/28 and CD19.CAR/28137 T cells Zanubrutinib and Lisocabtagene Maraleucel for the Treatment of Richter's Syndrome NCT05873712Phase 23 sites๐Ÿ“ New York๐Ÿ“ Columbus๐Ÿ“ Salt Lake City Aseel Alsouqi ยท Tests: Biospecimen Collection, Bone Marrow Biopsy, Computed Tomography, Cyclophosphamide, Fludarabine Pomalidomide After CAR T-cell Therapy for the Treatment of Relapsed or Refractory CD19+ B-cell Leukemia or Lymphoma NCT07532525Phase 11 site๐Ÿ“ Ann Arbor University of Michigan Rogel Cancer Center ยท Tests: Biospecimen Collection, Pomalidomide A Study of AC676 for the Treatment of Relapsed/Refractory B-Cell Malignancies NCT05780034Phase 19 sites๐Ÿ“ Denver๐Ÿ“ Sarasota๐Ÿ“ Chapel Hill Accutar Biotechnology Inc ยท Tests: AC676 Phase 1 Study of BAFF CAR-T Cells (LMY-920) for Treatment of Relapsed or Refractory Chronic Lymphocytic Leukemia / Small Lymphocytic Lymphoma NCT06916767Phase 11 site๐Ÿ“ Cleveland Paolo Caimi, MD ยท Tests: BAFF CAR-T, Obinutuzumab, Cyclophosphamide, Fludarabine Study of SLS009 (Formerly GFH009) a Potent Highly Selective CDK9 Inhibitor in Patients With Hematologic Malignancies and High-Risk Newly Diagnosed AML NCT04588922Phase 1, Phase 232 sites๐Ÿ“ Birmingham๐Ÿ“ Goodyear๐Ÿ“ Phoenix Sellas Life Sciences Group ยท Tests: SLS009, venetoclax, azacitidine Phase I/II Open-label Study Evaluating The Safety And Efficacy of Concomitant Administration of Anti-CD19 CAR T-cell Therapy and Lenalidomide in Refractory/Relapsed Chronic Lymphocytic Leukemia Patients. NCT06762431Phase 1, Phase 21 site๐Ÿ“ Vitebsk Vitebsk Regional Clinical Cancer Centre ยท Tests: Lenalidomide, Lenalidomide, Obinutuzumab Injection [Gazyva] Testing the Effectiveness of the Anti-cancer Drug, Mirdametinib, in Treating Relapsed, Refractory Chronic Lymphocytic Leukemia NCT07061951Phase 29 sites๐Ÿ“ Duarte๐Ÿ“ Irvine๐Ÿ“ Sacramento National Cancer Institute (NCI) ยท Tests: Biospecimen Collection, Bone Marrow Biopsy, Computed Tomography, Echocardiography Test, Mirdametinib A Study of Lonitoclax (ZE50-0134) in Relapsed or Refractory B-cell Malignancies NCT06708897Phase 15 sites๐Ÿ“ Louisville๐Ÿ“ Chapel Hill๐Ÿ“ Cincinnati Lomond Therapeutics Holdings, Inc. ยท Tests: Lonitoclax (ZE50-0134) Intravenous Autologous CD19 CAR-T Cells for R/ R MM, B-ALL, and B-Cell Lymphoma NCT06961669NA1 site๐Ÿ“ Hefei Anhui Provincial Hospital ยท Tests: Anti-BCMA and CD19 CART cells will be injected intravenously on a one-time basis Acalabrutinib and Venetoclax With or Without Early Obinutuzumab for the Treatment of High Risk, Recurrent, or Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma NCT04169737Phase 21 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Acalabrutinib, Obinutuzumab, Venetoclax
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