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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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27 recruiting trials

for Recurrent Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

Tissue, Blood, and Body Fluid Sample Collection From Patients With Hematologic Cancer NCT01137643n/a1 site๐Ÿ“ Chapel Hill UNC Lineberger Comprehensive Cancer Center ยท Tests: biologic sample preservation procedure, cytology specimen collection procedure A Study to Evaluate Safety, PK, PD and Efficacy of AZD5492, a T Cell-engaging Antibody Targeting CD20 in Subjects With R/R B-Cell Malignancies. NCT06542250Phase 1, Phase 231 sites๐Ÿ“ La Jolla๐Ÿ“ Boston๐Ÿ“ Rochester AstraZeneca ยท Tests: AZD5492 A Study of Lacutoclax (LP-108) in Patients With Relapsed/Refractory CLL/SLL NCT07609823Phase 21 site๐Ÿ“ Nanjing Guangzhou Lupeng Pharmaceutical Company LTD. ยท Tests: Lacutoclax Sonrotoclax, Rituximab, and Zanubrutinib in Treating Participants With Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, and Mantle Cell Lymphoma NCT06839053Phase 21 site๐Ÿ“ Seattle Fred Hutchinson Cancer Center ยท Tests: Biospecimen Collection, Bone Marrow Biopsy, Computed Tomography, Gastrointestinal Endoscopy, Rituximab Allo HSCT Using RIC and PTCy for Hematological Diseases NCT05805605Phase 21 site๐Ÿ“ Minneapolis Masonic Cancer Center, University of Minnesota ยท Tests: Peripheral Blood Stem Cell Transplant, Allopurinol 300 MG, Fludarabine, Cyclophosphamide, Bone Marrow Cell Transplant Testing the Effectiveness of the Anti-cancer Drug, Mirdametinib, in Treating Relapsed, Refractory Chronic Lymphocytic Leukemia NCT07061951Phase 29 sites๐Ÿ“ Duarte๐Ÿ“ Irvine๐Ÿ“ Sacramento National Cancer Institute (NCI) ยท Tests: Biospecimen Collection, Bone Marrow Biopsy, Computed Tomography, Echocardiography Test, Mirdametinib B-Cell Activating Factor Receptor (BAFFR)-Based Chimeric Antigen Receptor T-Cells With Fludarabine and Cyclophosphamide Lymphodepletion for the Treatment of Relapsed or Refractory B-cell Hematologic Malignancies NCT06191887Phase 11 site๐Ÿ“ Jacksonville Mayo Clinic ยท Tests: Autologous BAFFR-targeting CAR T Cells, Bendamustine, Biopsy, Biospecimen Collection, Bone Marrow Aspiration and Biopsy Phase Ib Clinical Study of Keynatinib NCT04807881Phase 14 sites๐Ÿ“ Beijing๐Ÿ“ Beijing๐Ÿ“ Shanghai Medolution Ltd. ยท Tests: Keynatinib CD19-Directed CAR-T Cell Therapy for the Treatment of Relapsed/Refractory B Cell Malignancies NCT04892277Phase 11 site๐Ÿ“ Rochester Mayo Clinic ยท Tests: Autologous Anti-CD19 CAR-expressing T-lymphocytes IC19/1563, Bendamustine, Biospecimen Collection, Bone Marrow Aspiratiโ€ฆ Registry of Older Patients With Cancer NCT01137825n/a7 sites๐Ÿ“ Boone๐Ÿ“ Chapel Hill๐Ÿ“ Greenville UNC Lineberger Comprehensive Cancer Center Phase 1 Study of BAFF CAR-T Cells (LMY-920) for Treatment of Relapsed or Refractory Chronic Lymphocytic Leukemia / Small Lymphocytic Lymphoma NCT06916767Phase 11 site๐Ÿ“ Cleveland Paolo Caimi, MD ยท Tests: BAFF CAR-T, Obinutuzumab, Cyclophosphamide, Fludarabine Acalabrutinib in Combination With Venetoclax for the Treatment of Refractory or Recurrent Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma, The AVENUE-2 Trial NCT04941716Phase 21 site๐Ÿ“ Seattle Fred Hutchinson Cancer Center ยท Tests: Acalabrutinib, Venetoclax, Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy Q702 for the Treatment of Patients With Hematologic Malignancies NCT06712810Phase 12 sites๐Ÿ“ Scottsdale๐Ÿ“ Rochester Mayo Clinic ยท Tests: Axl/Mer/CSF1R Inhibitor Q702, Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy, Computed Tomography Phase I/II Open-label Study Evaluating The Safety And Efficacy of Concomitant Administration of Anti-CD19 CAR T-cell Therapy and Lenalidomide in Refractory/Relapsed Chronic Lymphocytic Leukemia Patients. NCT06762431Phase 1, Phase 21 site๐Ÿ“ Vitebsk Vitebsk Regional Clinical Cancer Centre ยท Tests: Lenalidomide, Lenalidomide, Obinutuzumab Injection [Gazyva] A Study of AC676 for the Treatment of Relapsed/Refractory B-Cell Malignancies NCT05780034Phase 19 sites๐Ÿ“ Denver๐Ÿ“ Sarasota๐Ÿ“ Chapel Hill Accutar Biotechnology Inc ยท Tests: AC676 Study of Oral Administration of LP-118 in Patients With Relapsed or Refractory CLL, SLL, MDS, MDS/MPN, AML, CMML-2, MPN-BP, ALL, MF, NHL, RT, MM or T-PLL. NCT04771572Phase 18 sites๐Ÿ“ Chicago๐Ÿ“ Boston๐Ÿ“ Chapel Hill Newave Pharmaceutical Inc ยท Tests: LP-118 Study of TBI-2001(Autologous CD19 Specific Chimeric Antigen Receptor (CAR) Gene-transduced T Lymphocytes) for Relapsed or Refractory CD19+ B-cell Lymphoma, CLL/SLL NCT05963217Phase 11 site๐Ÿ“ Toronto University Health Network, Toronto ยท Tests: TBI-2001, Cyclophosphamide, Fludarabine Phase II Study of Combined Pirtobrutinib, Venetoclax and Obinutuzumab (PVO) Time-limited Treatment for Patients With Recurrent Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL). NCT06967610Phase 21 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Pirtobrutinib, Venetoclax, Obinutuzumab ROCKET-CLL Global Phase 3 Study: Rocbrutinib vs Pirtobrutinib in cBTKi-Pretreated R/R CLL/SLL NCT07342478Phase 36 sites๐Ÿ“ Skokie๐Ÿ“ Bethesda๐Ÿ“ Las Vegas Newave Pharmaceutical Inc ยท Tests: Rocbrutinib, Pirtobrutinib Nemtabrutinib and Lisocabtagene Maraleucel for the Treatment of Relapsed/Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma NCT07194980Phase 21 site๐Ÿ“ Seattle Fred Hutchinson Cancer Center ยท Tests: Nemtabrutinib, Lisocabtagene Maraleucel Acalabrutinib and Venetoclax With or Without Early Obinutuzumab for the Treatment of High Risk, Recurrent, or Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma NCT04169737Phase 21 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Acalabrutinib, Obinutuzumab, Venetoclax Study of SLS009 (Formerly GFH009) a Potent Highly Selective CDK9 Inhibitor in Patients With Hematologic Malignancies and High-Risk Newly Diagnosed AML NCT04588922Phase 1, Phase 232 sites๐Ÿ“ Birmingham๐Ÿ“ Goodyear๐Ÿ“ Phoenix Sellas Life Sciences Group ยท Tests: SLS009, venetoclax, azacitidine Zanubrutinib in Combination With Sonrotoclax for the Treatment of Underrepresented Ethnic and Racial Minorities With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma NCT06859008Phase 11 site๐Ÿ“ Duarte City of Hope Medical Center ยท Tests: Biopsy, Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy, Computed Tomography MAVRiC Studies 2L Treatment With AV in Patients With CLL/SLL Who Have Relapsed After a Course of BTKi + BCL2i Combination, With or Without Obinutuzumab NCT07024706Phase 247 sites๐Ÿ“ Boston๐Ÿ“ Charlotte๐Ÿ“ Charlotte AstraZeneca ยท Tests: Acalabrutinib, Venetoclax Dose Determining Study of EXS73565 in Participants With Relapsed or Refractory B-Cell Malignancies NCT06980116Phase 117 sites๐Ÿ“ Tbilisi๐Ÿ“ Athens๐Ÿ“ Pรกtrai Exscientia AI Ltd., a wholly owned subsidiary of Recursion โ€ฆ ยท Tests: EXS73565 A Study of APG-3288 in Relapsed/Refractory Blood Cancers NCT07424833Phase 16 sites๐Ÿ“ Los Angeles๐Ÿ“ Jacksonville๐Ÿ“ Grand Rapids Ascentage Pharma Group Inc. ยท Tests: APG-3288 A Study of Lonitoclax (ZE50-0134) in Relapsed or Refractory B-cell Malignancies NCT06708897Phase 15 sites๐Ÿ“ Louisville๐Ÿ“ Chapel Hill๐Ÿ“ Cincinnati Lomond Therapeutics Holdings, Inc. ยท Tests: Lonitoclax (ZE50-0134)
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