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Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Relapsed Adult Acute Myeloid Leukemia

Chemotherapy (Decitabine in Combination With FLAG-Ida) and Total-Body Irradiation Followed by Donor Stem Cell Transplant for the Treatment of Adults With Myeloid Malignancies at High Risk of Relapse NCT06928662Phase 1, Phase 21 site๐Ÿ“ Seattle Fred Hutchinson Cancer Center ยท Tests: Decitabine, Bone Marrow Aspiration, Bone Marrow Biopsy, Chest Radiography, Cytarabine Venetoclax Basket Trial for High Risk Hematologic Malignancies NCT05292664Phase 15 sites๐Ÿ“ San Francisco๐Ÿ“ Aurora๐Ÿ“ Atlanta Andrew E. Place, MD ยท Tests: Venetoclax, Azacitidine, Cytarabine, Methotrexate, Hydrocortisone Venetoclax Combining Chidamide and Azacitidine (VCA) in the Treatment of R/R AML NCT05305859Phase 21 site๐Ÿ“ Xiamen The First Affiliated Hospital of Xiamen University ยท Tests: venetoclax combining chidamide and azacitidine (VCA) PLAT-08: A Study Of SC-DARIC33 CAR T Cells In Pediatric And Young Adults With Relapsed Or Refractory CD33+ AML NCT05105152Phase 11 site๐Ÿ“ Seattle Seattle Children's Hospital ยท Tests: SC-DARIC33 Novel Digital Application for Patients With Acute Leukemia NCT06472128NA3 sites๐Ÿ“ Boston๐Ÿ“ Durham๐Ÿ“ Seattle Massachusetts General Hospital ยท Tests: DREAMLAND, VITAL WELLNESS HA-1 T TCR T Cell Immunotherapy for the Treatment of Patients With Relapsed or Refractory Acute Leukemia After Donor Stem Cell Transplant NCT03326921Phase 11 site๐Ÿ“ Seattle Fred Hutchinson Cancer Center ยท Tests: CD8+ and CD4+ Donor Memory T-cells-expressing HA1-Specific TCR, Bone Marrow Aspiration, Biospecimen Collection Study of Oral PCLX-001 in R/R Acute Myeloid Leukemia NCT06613217Phase 11 site๐Ÿ“ Houston Pacylex Pharmaceuticals ยท Tests: zelenirstat Clinical Trial of WBC100 Capsule in Relapsed/Refractory Acute Myeloid Leukemia NCT07014449Phase 11 site๐Ÿ“ Hangzhou Hangzhou Weben Pharma Co., Ltd ยท Tests: WBC100 QD A Study of BH-30236 in Relapsed/ Refractory Acute Myelogenous Leukemia and Higher Risk Myelodysplastic Syndrome NCT06501196Phase 113 sites๐Ÿ“ Duarte๐Ÿ“ Los Angeles๐Ÿ“ Palo Alto BlossomHill Therapeutics ยท Tests: BH-30236, Venetoclax CD64 CAR T Cell Therapy in Adults With Relapsed and/or Refractory AML NCT07347418Phase 11 site๐Ÿ“ Aurora University of Colorado, Denver ยท Tests: CD64 CAR T Cells Clinical Trial to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Tuspetinib (HM43239) in Patients With Relapsed or Refractory Acute Myeloid Leukemia NCT03850574Phase 1, Phase 234 sites๐Ÿ“ Birmingham๐Ÿ“ Duarte๐Ÿ“ Irvine Aptose Biosciences Inc. ยท Tests: Tuspetinib, Venetoclax Oral Tablet, Azacitidine for Intravenous Infusion Personalized NK Cell Therapy in CBT NCT02727803Phase 21 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Allogeneic Natural Killer Cell Line NK-92, Anti-Thymocyte Globulin, Busulfan, Clofarabine, Cyclophosphamide Acute Myeloid Leukemia At Initial Diagnosis and/or Relapse in Children, Teenagers and Young Adults: Molecular Profiling, Multidrug Testing and MSC Interaction Studies NCT05772559n/a28 sites๐Ÿ“ Amiens๐Ÿ“ Angers๐Ÿ“ Besanรงon Assistance Publique - Hรดpitaux de Paris ยท Tests: Collection of blood sample of bone marrow (cohort 1), Collection of blood sample of bone marrow (cohort 2 and 3) Adaptive Dual-Target CAR-T Cells for Relapsed or Refractory Hematologic Malignancies NCT07523555Phase 1, Phase 21 site๐Ÿ“ Shenzhen Beijing Biotech ยท Tests: Autologous CD19/CD22 dual-target CAR-T module, Autologous CD19/CD20 dual-target CAR-T module, Autologous BCMA/CD19 dualโ€ฆ A Prospective, Multicenter, and Exploratory Study of CMGV in the Treatment of Recurrent Adult AML and MDS-EB-2/Elder AML NCT06329999NA1 site๐Ÿ“ Shanghai Ruijin Hospital ยท Tests: CMGV Intensity Modulated Total Marrow Irradiation in Fully Human Leukocyte Antigen (HLA)-Matched and Partially-HLA Mismatched Allogeneic Transplantation Patients With High-Risk Acute Myeloid Leukemia (AML), Chronic Myeloid Leukemia (CML), and Myelodysplastic Syndrome (MDS) NCT06802315Phase 21 site๐Ÿ“ Chicago University of Illinois at Chicago ยท Tests: Intensity modulated total marrow irradiation, Cyclophosphamide (CTX), Fludarabine (Fludara), Busulfan (conditioning forโ€ฆ Dose Escalation and Expansion Study to Evaluate the Safety, PK, PD and Efficacy of ZE46-0134 in Adults With FLT3 Mutated or Spliceosome Mutated Relapsed or Refractory Acute Myeloid Leukemia NCT06366789Phase 123 sites๐Ÿ“ Los Angeles๐Ÿ“ San Francisco๐Ÿ“ Atlanta Lomond Therapeutics Holdings, Inc. ยท Tests: ZE46-0134 A Study to Investigate APL-4098 Alone and in Combination in Adults With AML or MDS NCT06372717Phase 19 sites๐Ÿ“ Clayton๐Ÿ“ Fitzroy๐Ÿ“ Melbourne Apollo Therapeutics Ltd ยท Tests: APL-4098, Azacitidine and APL-4098, Azacitidine and Venetoclax and APL-4098 A Vaccine (VSV-hIFNฮฒ-NIS) With or Without Cyclophosphamide and Combinations of Ipilimumab, Nivolumab, and Cemiplimab in Treating Relapsed or Refractory Multiple Myeloma, Acute Myeloid Leukemia or Lymphoma NCT03017820Phase 12 sites๐Ÿ“ Scottsdale๐Ÿ“ Rochester Mayo Clinic ยท Tests: Biopsy Procedure, Biospecimen Collection, Bone Marrow Biopsy, Computed Tomography, Cyclophosphamide Study Investigating the Safety of CD19 CAR-T Cells in Relapsed/Refractory AML Expressing CD19 NCT06649227Phase 11 site๐Ÿ“ Lille University Hospital, Lille ยท Tests: CAR-T cell therapy CLAG-M or FLAG-Ida Chemotherapy and Reduced-Intensity Conditioning Donor Stem Cell Transplant for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Chronic Myelomonocytic Leukemia NCT04375631Phase 11 site๐Ÿ“ Seattle Fred Hutchinson Cancer Center ยท Tests: Cladribine, Cyclophosphamide, Cyclosporine, Cytarabine, Filgrastim Pharmacokinetic and Safety Study of MRX-2843 in Adolescents and Adults With Relapsed/Refractory AML, ALL, or MPAL NCT04872478Phase 13 sites๐Ÿ“ Atlanta๐Ÿ“ Atlanta๐Ÿ“ New York Meryx, Inc. ยท Tests: MRX-2843 MiRisten for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia NCT07025564Phase 11 site๐Ÿ“ Duarte City of Hope Medical Center ยท Tests: Biospecimen Collection, Echocardiography Test, miR-126 Inhibitor miRisten CD33-CAR T Cell Therapy for the Treatment of Recurrent or Refractory Acute Myeloid Leukemia NCT05672147Phase 11 site๐Ÿ“ Duarte City of Hope Medical Center ยท Tests: Anti-CD33 CAR T-cells, Lymphodepletion Therapy First-in-human Study Aiming to Characterize the Safety, Tolerability, Pharmacokinetic and Preliminary Signs of Activity of ABD-3001 in Refractory or Relapsed AML and High Risk MDS Adult Patients NCT05601726Phase 1, Phase 23 sites๐Ÿ“ Marseille๐Ÿ“ Paris๐Ÿ“ Pierre-Bรฉnite Advanced BioDesign ยท Tests: ABD-3001, ABD-3001 Specialty Compared to Oncology Delivered Palliative Care for Patients With Acute Myeloid Leukemia NCT05237258NA20 sites๐Ÿ“ Birmingham๐Ÿ“ Stanford๐Ÿ“ Denver Massachusetts General Hospital ยท Tests: Specialty Palliative Care, Primary Palliative Care Adapt NK for High Risk Myeloid Diseases as Bridge to Allo HSCT NCT07591649Phase 1, Phase 21 site๐Ÿ“ Minneapolis Masonic Cancer Center, University of Minnesota ยท Tests: AdaptNK, Fludarabine, Cyclophosphamide, IL-2 Venetoclax Combined With Vyxeos (CPX-351) for Participants With Relapsed or Refractory Acute Leukemia NCT03826992Phase 11 site๐Ÿ“ Cincinnati Children's Hospital Medical Center, Cincinnati ยท Tests: Vyxeos, Venetoclax A Phase 1 Study of CG009301 for Injection in Adult Subjects With Recurrent or Refractory Haematological Malignancies NCT07347171Phase 13 sites๐Ÿ“ Nanchang๐Ÿ“ Tianjin๐Ÿ“ Wuhan Cullgen (Shanghai),Inc ยท Tests: CG009301 for Injection Sequential CAR-T Cells Targeting CD33/CD123 in Patients With Acute Myelocytic Leukemia AML NCT06420063Phase 1, Phase 21 site๐Ÿ“ Beijing Essen Biotech ยท Tests: CD123/CD33 CART
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