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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Relapsed or Refractory Acute Myeloid Leukemia (AML)

Vyxeos Plus Gilteritinib in Relapsed or Refractory, FLT3-Mutated AML NCT05024552Phase 11 site๐Ÿ“ Tampa H. Lee Moffitt Cancer Center and Research Institute ยท Tests: Gilteritinib, Vyxeos CD180 CART for Relapsed or Refractory CD180 Positive Hematologic Malignancies NCT07106749Phase 11 site๐Ÿ“ Tianjin Institute of Hematology & Blood Diseases Hospital, China ยท Tests: CD180 CART A Pilot Study of Soursop Tea in Patients With Relapsed/Refractory Acute Myeloid Leukemia (AML) or Multiple Myeloma (MM) NCT07771803EARLY Phase 11 site๐Ÿ“ Camden Roger Strair ยท Tests: Soursop tea A Phase Ib Study of APG-115 Single Agent or in Combination With Azacitidine or Cytarabine in Patients With AML and MDS. NCT04275518Phase 114 sites๐Ÿ“ Beijing๐Ÿ“ Guangzhou๐Ÿ“ Guangzhou Ascentage Pharma Group Inc. ยท Tests: APG-115, Azacitidine, Cytarabine Venetoclax Basket Trial for High Risk Hematologic Malignancies NCT05292664Phase 15 sites๐Ÿ“ San Francisco๐Ÿ“ Aurora๐Ÿ“ Atlanta Andrew E. Place, MD ยท Tests: Venetoclax, Azacitidine, Cytarabine, Methotrexate, Hydrocortisone Off-the-shelf CD123 CAR-NK for R/R AML NCT06201247EARLY Phase 11 site๐Ÿ“ Beijing Peking University People's Hospital ยท Tests: JD123 injection Clinical Study of ARD103 CAR-T Therapy for Patients With R/R AML or MDS NCT06680752Phase 1, Phase 23 sites๐Ÿ“ Charlotte๐Ÿ“ Winston-Salem๐Ÿ“ Houston ARCE Therapeutics, Inc. ยท Tests: ARD103, Cyclophosphamide, Fludarabine PLAT-08: A Study Of SC-DARIC33 CAR T Cells In Pediatric And Young Adults With Relapsed Or Refractory CD33+ AML NCT05105152Phase 11 site๐Ÿ“ Seattle Seattle Children's Hospital ยท Tests: SC-DARIC33 IMPACT-AML: A Randomized Pragmatic Clinical Trial for Relapsed or Refractory Acute Myeloid Leukemia. NCT06713837Phase 347 sites๐Ÿ“ Brno๐Ÿ“ Hradec Krรกlovรฉ๐Ÿ“ Olomouc Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRโ€ฆ ยท Tests: High intensity therapies, Low intensity therapies Decitabine/Cedazuridine and Venetoclax in Combination With Ivosidenib or Enasidenib for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia NCT04774393Phase 1, Phase 21 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Decitabine and Cedazuridine, Enasidenib, Ivosidenib, Venetoclax HA-1 T TCR T Cell Immunotherapy for the Treatment of Patients With Relapsed or Refractory Acute Leukemia After Donor Stem Cell Transplant NCT03326921Phase 11 site๐Ÿ“ Seattle Fred Hutchinson Cancer Center ยท Tests: CD8+ and CD4+ Donor Memory T-cells-expressing HA1-Specific TCR, Bone Marrow Aspiration, Biospecimen Collection A Study to Investigate the Safety and Tolerability of Ziftomenib in Combination With Venetoclax/Azacitidine, Venetoclax, 7+3, or 7+3+Quizartinib in Patients With AML NCT05735184Phase 144 sites๐Ÿ“ Phoenix๐Ÿ“ La Jolla๐Ÿ“ Los Angeles Kura Oncology, Inc. ยท Tests: Ziftomenib, Venetoclax, Azacitidine, Daunorubicin, Cytarabine SL-401 in Combination With Azacitidine or Azacitidine/Venetoclax in Acute Myeloid Leukemia (AML), High-Risk Myelodysplastic Syndrome (MDS) or Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) NCT03113643Phase 13 sites๐Ÿ“ Duarte๐Ÿ“ Boston๐Ÿ“ Houston Dana-Farber Cancer Institute ยท Tests: Azacitidine, SL-401, Venetoclax First-in-human (FIH) Trial of GEN3018 in Relapsed or Refractory (R/R) Acute Myeloid Leukemia (AML) or Higher-risk Myelodysplastic Syndrome (HR-MDS) NCT07384715Phase 16 sites๐Ÿ“ Aarhus๐Ÿ“ Copenhagen๐Ÿ“ Barcelona Genmab ยท Tests: GEN3018 Clinical Trial of WBC100 Capsule in Relapsed/Refractory Acute Myeloid Leukemia NCT07014449Phase 11 site๐Ÿ“ Hangzhou Hangzhou Weben Pharma Co., Ltd ยท Tests: WBC100 QD SupCD7 CART for Relapsed or Refractory CD7 Positive Hematologic Malignancies NCT07153068Phase 1, Phase 21 site๐Ÿ“ Tianjin Institute of Hematology & Blood Diseases Hospital, China ยท Tests: supCD7 CART cells Quizartinib, Decitabine, and Venetoclax in Treating Participants With Untreated or Relapsed Acute Myeloid Leukemia or High Risk Myelodysplastic Syndrome NCT03661307Phase 1, Phase 21 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Decitabine, Quizartinib, Venetoclax A Study of BH-30236 in Relapsed/ Refractory Acute Myelogenous Leukemia and Higher Risk Myelodysplastic Syndrome NCT06501196Phase 113 sites๐Ÿ“ Duarte๐Ÿ“ Los Angeles๐Ÿ“ Palo Alto BlossomHill Therapeutics ยท Tests: BH-30236, Venetoclax CD64 CAR T Cell Therapy in Adults With Relapsed and/or Refractory AML NCT07347418Phase 11 site๐Ÿ“ Aurora University of Colorado, Denver ยท Tests: CD64 CAR T Cells Safety and Tolerability of Ziftomenib Combinations in Patients With Relapsed/Refractory Acute Myeloid Leukemia NCT06001788Phase 145 sites๐Ÿ“ Gilbert๐Ÿ“ Los Angeles๐Ÿ“ Los Angeles Kura Oncology, Inc. ยท Tests: Ziftomenib, Fludarabine, Idarubicin, Cytarabine, Gilteritinib Venetoclax With Combination Chemotherapy in Treating Patients With Newly Diagnosed or Relapsed or Refractory Acute Myeloid Leukemia NCT03214562Phase 1, Phase 21 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Cytarabine, Filgrastim, Fludarabine, Idarubicin, Pegfilgrastim Clinical Trial to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Tuspetinib (HM43239) in Patients With Relapsed or Refractory Acute Myeloid Leukemia NCT03850574Phase 1, Phase 234 sites๐Ÿ“ Birmingham๐Ÿ“ Duarte๐Ÿ“ Irvine Aptose Biosciences Inc. ยท Tests: Tuspetinib, Venetoclax Oral Tablet, Azacitidine for Intravenous Infusion Genetically Engineered Cells (CD83 CAR T Cells) for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia NCT06871410Phase 11 site๐Ÿ“ Buffalo Roswell Park Cancer Institute ยท Tests: Autologous Anti-CD83 CAR T-cells, Biospecimen Collection, Chest Radiography, Computed Tomography, Cyclophosphamide Phase I Study of FXS0683 in the Treatment of Blood Tumors NCT07616089Phase 11 site๐Ÿ“ Tianjin Shanghai Fosun Pharmaceutical Industrial Development Co. Ltโ€ฆ ยท Tests: FXS0683 Adaptive Dual-Target CAR-T Cells for Relapsed or Refractory Hematologic Malignancies NCT07523555Phase 1, Phase 21 site๐Ÿ“ Shenzhen Beijing Biotech ยท Tests: Autologous CD19/CD22 dual-target CAR-T module, Autologous CD19/CD20 dual-target CAR-T module, Autologous BCMA/CD19 dualโ€ฆ Master Framework For Relapse or Refractory Acute Myeloid Leukemia NCT06459024n/a40 sites๐Ÿ“ Aachen๐Ÿ“ Greifswald๐Ÿ“ Halle Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRโ€ฆ ยท Tests: Registration into the STREAM platform Study of Lisaftoclax (APG-2575) Single Agent and Combination With Therapy in Patients Relapsed/Refractory AML NCT04501120Phase 1, Phase 212 sites๐Ÿ“ Beijing๐Ÿ“ Chongqing๐Ÿ“ Guangzhou Ascentage Pharma Group Inc. ยท Tests: Lisaftoclax (APG-2575), Reduced-dose HHT, standard-dose HHT, Azacitidine, Lisaftoclax (APG-2575) A Study to Assess Adverse Events and How Intravenous (IV) Pivekimab Sunirine Moves Through the Body in Pediatric Participants With Relapsed or Refractory Acute Myeloid Leukemia (AML) NCT07306832Phase 114 sites๐Ÿ“ Palo Alto๐Ÿ“ Atlanta๐Ÿ“ Valhalla AbbVie ยท Tests: Pivekimab Sunirine Tazemetostat and Palbociclib With CPX-351for R/R AML NCT05627232Phase 11 site๐Ÿ“ Philadelphia Thomas Jefferson University ยท Tests: Tazemetostat, Liposome-encapsulated Daunorubicin-Cytarabine, Bone Marrow Aspiration and Biopsy, Biospecimen Collection,โ€ฆ CD33KO-HSPC Infusion Followed by CART-33 Infusion(s) for Refractory/Relapsed AML NCT05945849Phase 11 site๐Ÿ“ Philadelphia University of Pennsylvania ยท Tests: CD33KO-HSPC; CART33
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