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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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23 recruiting trials

for Secondary AML

Chemotherapy (Decitabine in Combination With FLAG-Ida) and Total-Body Irradiation Followed by Donor Stem Cell Transplant for the Treatment of Adults With Myeloid Malignancies at High Risk of Relapse NCT06928662Phase 1, Phase 21 site๐Ÿ“ Seattle Fred Hutchinson Cancer Center ยท Tests: Decitabine, Bone Marrow Aspiration, Bone Marrow Biopsy, Chest Radiography, Cytarabine Venetoclax in Addition to Sequential Conditioning With Fludarabine / Amsacrine / Ara-C (FLAMSA) + Treosulfan for Allogeneic Blood Stem Cell Transplantation in Patients With MDS, CMML or sAML NCT05807932Phase 1, Phase 26 sites๐Ÿ“ Aachen๐Ÿ“ Dรผsseldorf๐Ÿ“ Cologne Heinrich-Heine University, Duesseldorf ยท Tests: Venetoclax, Amsacrine, Ara-C, Tacrolimus, Mycophenolate Mofetil Venetoclax Basket Trial for High Risk Hematologic Malignancies NCT05292664Phase 15 sites๐Ÿ“ San Francisco๐Ÿ“ Aurora๐Ÿ“ Atlanta Andrew E. Place, MD ยท Tests: Venetoclax, Azacitidine, Cytarabine, Methotrexate, Hydrocortisone Unrelated Umbilical Cord Blood Stem Cell Combined With Azacitidine Based Treatment for Advanced MDS,CMML-2 and sAML NCT05584761Phase 1, Phase 21 site๐Ÿ“ Nanjing The First Affiliated Hospital with Nanjing Medical Universiโ€ฆ ยท Tests: unrelated umbilical cord blood Total Marrow and Lymphoid Irradiation in Combination With Fludarabine and Melphalan as Conditioning for Allogeneic Peripheral Blood Stem Cell Hematopoietic Cell Transplant in Older Patients With Refractory and Relapsed Acute Myeloid Leukemia and High-risk Myelodysplastic Syndrome NCT07582172Phase 21 site๐Ÿ“ Duarte City of Hope Medical Center ยท Tests: Biospecimen Collection, Bone Marrow Biopsy, Computed Tomography, Echocardiography Test, Fludarabine Phosphate A Phase 1b Study of Menin Inhibitor SNDX- 5613 in Combination With Daunorubicin and Cytarabine in Newly Diagnosed Patients With Acute Myeloid Leukemia and NPM1 Mutated/FLT3 Wildtype or MLL/KMT2A Rearranged or NUP98 Alterations Disease NCT05886049Phase 123 sites๐Ÿ“ Orange๐Ÿ“ Sacramento๐Ÿ“ Aventura National Cancer Institute (NCI) ยท Tests: Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy, Cytarabine, Daunorubicin Edetate Calcium Disodium or Succimer in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome Undergoing Chemotherapy NCT03630991Phase 11 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Edetate Calcium Disodium, Multivitamin, Succimer Cladribine, Idarubicin, Cytarabine, and Venetoclax in Treating Patients With Acute Myeloid Leukemia, High-Risk Myelodysplastic Syndrome, or Blastic Phase Chronic Myeloid Leukemia NCT02115295Phase 21 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Cladribine, Cytarabine, Gilteritinib, Idarubicin, Laboratory Biomarker Analysis VAM in Secondary AML, AML With Extramedullary Involvement, and Myeloid Sarcoma NCT07028086Phase 21 site๐Ÿ“ Shanghai Ruijin Hospital ยท Tests: VAM_GROUP Personalized NK Cell Therapy in CBT NCT02727803Phase 21 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Allogeneic Natural Killer Cell Line NK-92, Anti-Thymocyte Globulin, Busulfan, Clofarabine, Cyclophosphamide Decitabine With Ruxolitinib, Fedratinib or Pacritinib for the Treatment of Accelerated/Blast Phase Myeloproliferative Neoplasms NCT04282187Phase 21 site๐Ÿ“ Seattle University of Washington ยท Tests: Decitabine, Ruxolitinib, Fedratinib, Questionnaire Administration, Pacritinib Darzalex Faspro (Daratumumab and Hyaluronidase-fihj) Before Standard Desensitization and Allogeneic Bone Marrow or Peripheral Blood Stem Cell Transplantation in Adult Patients at High-risk for Primary Graft Failure Secondary to Donor Specific Antibodies NCT06398457EARLY Phase 11 site๐Ÿ“ Baltimore Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins ยท Tests: Darzalex Faspro (Daratumumab and hyaluronidase-fihj), JH-DSA Semi-Quant Screen and Response Score A Study to Find the Highest Dose of Imetelstat in Combination With Fludarabine and Cytarabine for Patients With AML, MDS or JMML That Has Come Back or Does Not Respond to Therapy NCT06247787Phase 119 sites๐Ÿ“ Birmingham๐Ÿ“ Orange๐Ÿ“ San Francisco Children's Oncology Group ยท Tests: Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy, Cytarabine, Echocardiography Test CD33-CAR T Cell Therapy for the Treatment of Recurrent or Refractory Acute Myeloid Leukemia NCT05672147Phase 11 site๐Ÿ“ Duarte City of Hope Medical Center ยท Tests: Anti-CD33 CAR T-cells, Lymphodepletion Therapy Tagraxofusp and Azacitidine With Venetoclax in Newly Diagnosed Secondary AML After Hypomethylating Agents NCT05442216Phase 27 sites๐Ÿ“ Miami๐Ÿ“ Orlando๐Ÿ“ Buffalo Joshua Zeidner ยท Tests: Tagraxofusp, Azacitidine, Venetoclax The Patient Cohort of the National Center for Precision Medicine in Leukemia NCT05326919n/a3 sites๐Ÿ“ Bobigny๐Ÿ“ Paris๐Ÿ“ Paris Assistance Publique - Hรดpitaux de Paris ยท Tests: Biobanking L-Annamycin for Injection in Combination With Cytarabine Injection as Second Line Therapy for Remission Induction in Adult Subjects With Refractory/Relapsed AML NCT06788756Phase 2, Phase 328 sites๐Ÿ“ Birmingham๐Ÿ“ Miami๐Ÿ“ Augusta Moleculin Biotech, Inc. ยท Tests: Placebo in combination with Cytarabine Injection, Liposomal Annamycin Injection in combination with Cytarabine Injectioโ€ฆ Registry of Older Patients With Cancer NCT01137825n/a7 sites๐Ÿ“ Boone๐Ÿ“ Chapel Hill๐Ÿ“ Greenville UNC Lineberger Comprehensive Cancer Center Tissue, Blood, and Body Fluid Sample Collection From Patients With Hematologic Cancer NCT01137643n/a1 site๐Ÿ“ Chapel Hill UNC Lineberger Comprehensive Cancer Center ยท Tests: biologic sample preservation procedure, cytology specimen collection procedure Ruxolitinib in Combination With Venetoclax With and Without Azacitidine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia NCT03874052Phase 13 sites๐Ÿ“ Columbus๐Ÿ“ Portland๐Ÿ“ Dallas Jennifer Saultz ยท Tests: Azacitidine, Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy, Echocardiography Test Cancer Experience Registry (CER) for Cancer Patients and Caregivers NCT02333604n/a1 site๐Ÿ“ Washington D.C. Cancer Support Community, Research and Training Institute, โ€ฆ Biomarker-Guided Allogeneic Single-Target or Dual-Target CAR-NK Cell Therapy for Advanced Solid Tumors NCT07410494Phase 1, Phase 21 site๐Ÿ“ Beijing Essen Biotech ยท Tests: EB-SELECT Single-Target CAR-NK Cells, Dual-Target Antigen-Selected CAR-NK A Study of Rebecsinib for Patients With Relapsed/Refractory Secondary Acute Myeloid Leukemia or High Risk Myelofibrosis NCT07250646Phase 13 sites๐Ÿ“ Duarte๐Ÿ“ Sacramento๐Ÿ“ San Diego Aspera Biomedicines, Inc. ยท Tests: rebecsinib
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