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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

Know your stage or your test results (such as EGFR, HER2 or BRCA)? Match trials to your own profile - nothing you type is saved.

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30 recruiting trials

for Severe COVID-19

A Multicenter, Randomized, Double-Blind, Placebo-Controlled Clinical Study to Evaluate the Safety and Efficacy of Uterine Blood Mesenchymal Stem Cells Injection for the Treatment of Severe Pneumonia Caused by Viruses NCT06693362Phase 11 site๐Ÿ“ Shanghai Ruijin Hospital ยท Tests: Placebo, Drug therapy, Standard Treatment A Study on Paxlovid Once in the Market, to Observe Its Safety and Effectiveness in Patients Who Have a High Chance of Getting Severe COVID-19 NCT05890612n/a1 site๐Ÿ“ Seoul Pfizer A Study to Learn About the Study Medicine Ibuzatrelvir in Adults With COVID-19 Who Are Severely Immunocompromised NCT07013474Phase 3159 sites๐Ÿ“ Canoga Park๐Ÿ“ Granada Hills๐Ÿ“ La Jolla Pfizer ยท Tests: ibuzatrelvir, remdesivir, placebo for ibuzatrelvir, placebo for remdesivir A Study of Secutrelvir in Participants With Coronavirus Disease 2019 (COVID-19) Who Are at High Risk for Progression to Severe Disease NCT07743580Phase 347 sites๐Ÿ“ Coral Gables๐Ÿ“ Miami๐Ÿ“ Miami Shionogi ยท Tests: Secutrelvir, Placebo Presynaptic Imaging in Major Depressive Episodes After COVID-19 NCT06086366n/a1 site๐Ÿ“ Toronto Centre for Addiction and Mental Health ยท Tests: [11C]DTBZ PET scan, [18F]SDM8 PET scan, MRI scan The Role of Obesity in Severe COVID-19 Pathophysiology NCT06968442NA1 site๐Ÿ“ Rotterdam Franciscus Gasthuis ยท Tests: Venipuncture A Study to Learn About a Study Medicine Called Ibuzatrelvir in Adult and Adolescent Patients With COVID-19 Who Are Not Hospitalized But Are at Risk For Severe Disease NCT06679140Phase 3256 sites๐Ÿ“ Huntsville๐Ÿ“ Little Rock๐Ÿ“ Bakersfield Pfizer ยท Tests: ibuzatrelvir, placebo Study of S-892216 Long-acting Injectable (LAI) in Healthy Adult Participants NCT07093580Phase 13 sites๐Ÿ“ Cypress๐Ÿ“ Lenexa๐Ÿ“ Salt Lake City Shionogi ยท Tests: S-892216-LAI, Placebo Characterization of the IFN-I Response in Subjects Who Experienced Severe or Mild Forms of COVID-19 NCT06703034NA1 site๐Ÿ“ Lyon Hospices Civils de Lyon ยท Tests: Biological Sampling Sequelae of Sars-CoV-2 Infections NCT04442789n/a1 site๐Ÿ“ Giessen University of Giessen Efficacy and Safety of Tozorakimab in Patients Hospitalised for Viral Lung Infection Requiring Supplemental Oxygen NCT05624450Phase 3471 sites๐Ÿ“ Birmingham๐Ÿ“ Mobile๐Ÿ“ Phoenix AstraZeneca ยท Tests: Tozorakimab, Placebo Unhideยฎ Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research NCT04806620n/a1 site๐Ÿ“ Delafield Brain Inflammation Collaborative Impact of Post-ARDS Covid-19 Sedation on Persistent Neuroinflammation NCT05233605n/a1 site๐Ÿ“ Paris Assistance Publique - Hรดpitaux de Paris IMPACT-D+: Immune-Modulating and Psychometric Effects of Accelerated TMS in Depression Plus Comorbid Post-COVID-19 Condition NCT07197138NA1 site๐Ÿ“ Munich Max-Planck-Institute of Psychiatry ยท Tests: Intermittent theta-burst stimulation (iTBS) using PowerMAG 100 ppTMS Convalescent Plasma as a Possible Treatment for COVID-19 NCT04442191Phase 21 site๐Ÿ“ Chicago University of Illinois at Chicago ยท Tests: Convalescent plasma, Placebo SARS-COV-2 Infection in Kidney Transplant Recipients: a Brazilian Multicenter Study NCT04494776n/a1 site๐Ÿ“ Sรฃo Paulo Helio Tedesco Silva Junior A Clinical Study of Molnupiravir to Prevent Severe Illness From Coronavirus Disease 2019 (COVID-19) in People Who Are High Risk (MK-4482-023) NCT06667700Phase 3227 sites๐Ÿ“ Cullman๐Ÿ“ Paradise Valley๐Ÿ“ Phoenix Merck Sharp & Dohme LLC ยท Tests: Molnupiravir, Placebo Imaging Immune Activation in COVID-19 NCT04815096Phase 21 site๐Ÿ“ San Francisco CellSight Technologies, Inc. ยท Tests: [18F]F-AraG (2'-deoxy-2'-fluoro-9-ฮฒ-D-arabinofuranosylguanine) Determinants of SARS (Severe Acute Respiratory Syndrome)-COV2 (COVID-19) Persistence After Convalescence NCT04448145n/a1 site๐Ÿ“ New York Columbia University A Study Evaluating MDX2301 in Healthy Adults and Adults at Higher Risk for Severe COVID-19. NCT07445971Phase 12 sites๐Ÿ“ Las Vegas๐Ÿ“ Austin ModeX Therapeutics, An OPKO Health Company ยท Tests: MDX2301, Normal Saline, Normal Saline, MDX2301 EPIC-Peds: A Study to Learn About the Study Medicine Called PF-07321332 (Nirmatrelvir)/Ritonavir in Patients Under 18 Years of Age With COVID-19 That Are Not Hospitalized But Are at Risk for Severe Disease NCT05261139Phase 373 sites๐Ÿ“ Phoenix๐Ÿ“ Los Angeles๐Ÿ“ Los Angeles Pfizer ยท Tests: nirmatrelvir, ritonavir Send-In Sample Collection for Comprehensive Analyses of Innate and Adaptive Immune Responses During Acute COVID-19 and Convalescence NCT04582903n/a1 site๐Ÿ“ Rockville National Institute of Allergy and Infectious Diseases (NIAIโ€ฆ Safety and Effectiveness of a Remdesivir Treatment to Prevent Severe COVID-19 in Kidney Transplant Patients NCT07197164Phase 21 site๐Ÿ“ Badalona Fundaciรณn FLS de Lucha Contra el Sida, las Enfermedades Infโ€ฆ ยท Tests: Remdesivir (RDV) RCT for Yinqiaosan-Maxingganshitang in the Treatment of COVID-19 NCT05787327Phase 21 site๐Ÿ“ Hong Kong Chinese University of Hong Kong ยท Tests: Chinese Herb, Placebo Severe COVID-19 Infection in Children Presenting to EDs in Israel and England NCT06434701NA6 sites๐Ÿ“ Afula๐Ÿ“ Beersheba๐Ÿ“ Jerusalem Hadassah Medical Organization ยท Tests: Nasopharyngeal swab sampling for COVID-19 Study of a Recombinant Spike COVID-19 Vaccine With Matrix-M in Older Adults and People at Increased Risk of Severe COVID-19 NCT07861542Phase 420 sites๐Ÿ“ Fair Oaks๐Ÿ“ Doral๐Ÿ“ Atlanta Sanofi ยท Tests: Omicron Subvariant-Based SARS-CoV-2 Recombinant Spike Vaccine Adjuvanted With Matrix-M Defibrotide for the Treatment of Severe COVID-19 NCT04652115Phase 21 site๐Ÿ“ Boston Brigham and Women's Hospital ยท Tests: Defibrotide Long-Term Study of COVID-19 Infection and Long COVID NCT07781501n/a1 site๐Ÿ“ Chapel Hill University of North Carolina, Chapel Hill ยท Tests: This study is observational. Only patients who have previously tested positive for SARS-CoV-2 infection or are experienโ€ฆ Positron Emission Tomography (PET) Imaging of Neuroinflammation in Patients With Neurological Dysfunction After Severe Acute Respiratory Syndrome Coronavirus 2 (SARS CoV 2) Infection NCT05656105EARLY Phase 11 site๐Ÿ“ Birmingham University of Alabama at Birmingham ยท Tests: DPA-714 PET/MRI Influence of Nutritional Indices on the Prognosis of Patients With SARS-CoV-2 Infection NCT05835102n/a1 site๐Ÿ“ Chongqing Juan Kang
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