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Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Spinal and Bulbar Muscular Atrophy

Apa/Enza-short Study: Shorter Treatment With Androgen Receptor Pathway Inhibitor in Patients With Low-volume Metastatic Castration-sensitive Prostate Cancer NCT07260435Phase 326 sites๐Ÿ“ Alkmaar๐Ÿ“ Amersfoort๐Ÿ“ Amsterdam Nick Beije ยท Tests: ADT plus only 12 months of ARPI, ADT plus continued ARPI Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response NCT06592924Phase 3395 sites๐Ÿ“ Anchorage๐Ÿ“ Anchorage๐Ÿ“ Anchorage Canadian Cancer Trials Group ยท Tests: Abiraterone, Enzalutamide, Apalutamide, Darolutamide (BAY 1841788), Docetaxel Duration of Androgen Receptor Pathway Inhibitor and ADT With Metastasis Directed Therapy in Oligometastatic Cancer of the Prostate (DIRECT) NCT05404139Phase 22 sites๐Ÿ“ Toronto๐Ÿ“ Toronto University Health Network, Toronto ยท Tests: Abiraterone, Standard of Care SBRT and ADT, Atorvastatin Study Evaluating the Safety, Tolerability, and Efficacy of Xaluritamig in Combination With Androgen Receptor Pathway Inhibitors in Participants With Metastatic Hormone-sensitive Prostate Cancer NCT07140900Phase 116 sites๐Ÿ“ San Francisco๐Ÿ“ Boston๐Ÿ“ Minneapolis Amgen ยท Tests: Xaluritamig, Darolutamide, Abiraterone Adjuvant Rezvilutamide in Combination With Androgen Deprivation Therapy in Androgen Receptor-positive, High-risk Salivary Duct Carcinoma NCT06348264Phase 22 sites๐Ÿ“ Beijing๐Ÿ“ Beijing Peking University First Hospital ยท Tests: Rezvilutamide, Leuprolide Acetate Seviteronel in Combination With Chemotherapy in Androgen-receptor Positive Metastatic Triple-negative Breast Cancer NCT04947189Phase 1, Phase 21 site๐Ÿ“ Darlinghurst St Vincent's Hospital, Sydney ยท Tests: Seviteronel-D (Seivteronel in combination with dexamethasone), Docetaxel UK SMA Patient Registry NCT04292574n/a1 site๐Ÿ“ Newcastle upon Tyne Newcastle University ยท Tests: Patient Registry A Placebo-controlled Study of Clenbuterol in Spinal and Bulbar Muscular Atrophy NCT06169046Phase 21 site๐Ÿ“ Padova Gianni Soraru ยท Tests: Clenbuterol, Placebo Supraphysiologic Testosterone Priming Induces Darolutamide Extended Response NCT07142551Phase 21 site๐Ÿ“ Baltimore Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins ยท Tests: Testosterone cypionate, Luteinizing hormone-releasing hormone (LHRH) analogue, Darolutamide Abemaciclib in Combination With Bicalutamide for Androgen Receptor-positive, HER2-negative Metastatic Breast Cancer NCT05095207Phase 1, Phase 23 sites๐Ÿ“ New York๐Ÿ“ New York๐Ÿ“ New York Icahn School of Medicine at Mount Sinai ยท Tests: Abemaciclib, Bicalutamide Evaluation of Clinical Outcomes of Chemotherapy or Androgen-receptor Targeting Agent (Alone or Combined) or Radiotherapy on Primary Tumor in Addition to Androgen Deprivation Therapy in HOrmone-Sensitive Metastatic Prostate Cancer Patients NCT06473259n/a3 sites๐Ÿ“ Orbassano๐Ÿ“ Padova๐Ÿ“ Trento Santa Chiara Hospital ยท Tests: Docetaxel, Apalutamide Oral Tablet, Enzalutamide Oral Tablet, Abiraterone acetate tablets, Darolutamide Oral Tablet Study of PSMA-targeted Therapy and Androgen Receptor Suppression in Low-volume Metastatic ProstatE Cancer: SPARKLE Trial NCT07650240Phase 21 site๐Ÿ“ Rochester Mayo Clinic ยท Tests: Abiraterone Acetate, Biospecimen Collection, Leuprolide Acetate, Lutetium Lu 177 Vipivotide Tetraxetan, Prednisone A Study of JNJ-101556143 in Participants With Metastatic Prostate Cancer NCT07832292Phase 25 sites๐Ÿ“ Lafayette๐Ÿ“ Plymouth๐Ÿ“ Syracuse Janssen Research & Development, LLC ยท Tests: JNJ-101556143 Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford NCT01793168n/a2 sites๐Ÿ“ Sioux Falls๐Ÿ“ Sydney Sanford Health TherApeutics in Early ProState Cancer (TAPS02) NCT05191680Phase 26 sites๐Ÿ“ Cambridge๐Ÿ“ Bristol๐Ÿ“ Bury St Edmunds Cambridge University Hospitals NHS Foundation Trust ยท Tests: Apalutamide Oral Tablet [Erleada], Placebo High Cardiovascular Risk Intervention With Cardio-Oncology Consultation for Prostate Cancer Following Androgen Receptor Pathway Inhibitor (ARPI) Therapy (Heart-Safe) NCT07223385Phase 21 site๐Ÿ“ Los Angeles Cedars-Sinai Medical Center ยท Tests: Cardio-Oncology Referral, Notification to PCP/General Cardiologist An Observational Study to Learn More About How Medicines That Block Male Hormones Are Used in People With Prostate Cancer in Australia NCT07223372n/a1 site๐Ÿ“ Pymble Bayer A Study of Talazoparib With or Without Enzalutamide in People With Prostate Cancer Who Have Previously Received Abiraterone Acetate or Darolutamide NCT06844383Phase 28 sites๐Ÿ“ Duarte๐Ÿ“ La Jolla๐Ÿ“ Boston Prostate Cancer Clinical Trials Consortium ยท Tests: Talazoparib with enzalutamide, Talazoparib Novel ACK1 Inhibitor (R)-9b in Patients With Prostate Cancer NCT06705686Phase 11 site๐Ÿ“ Madison TechnoGenesys, Inc. ยท Tests: (R)-9bMS Stereotactic Body Radiation Therapy Plus Immediate or Delayed Androgen Receptor Pathway Inhibitor and Androgen Deprivation Therapy or Salvage Radiation Therapy for the Treatment of Prostate Cancer, DIVINE Trial NCT06378866Phase 23 sites๐Ÿ“ Phoenix๐Ÿ“ Jacksonville๐Ÿ“ Rochester Mayo Clinic ยท Tests: Abiraterone, Apalutamide, Biospecimen Collection, Bone Scan, Computed Tomography Androgen Receptor, Implications for Health and Wellbeing: Natural History Study of Individuals With Androgen Insensitivity NCT04708431n/a1 site๐Ÿ“ Bethesda Eunice Kennedy Shriver National Institute of Child Health aโ€ฆ Study of ORIC-944 in Patients With Metastatic Prostate Cancer NCT05413421Phase 127 sites๐Ÿ“ Colorado Springs๐Ÿ“ Plantation๐Ÿ“ Arlington Heights ORIC Pharmaceuticals ยท Tests: ORIC-944, Abiraterone acetate (Zytigaยฎ) 250 mg or 500 mg tablets, Apalutamide (Erleadaโ„ข) 60 mg or 240 mg tablets, Darolโ€ฆ Phase I/II Trial of Pembrolizumab and Androgen-receptor Inhibitor With or Without 225Ac-J591 for Progressive Metastatic Castration Resistant Prostate Cancer NCT04946370Phase 1, Phase 24 sites๐Ÿ“ Boston๐Ÿ“ Brooklyn๐Ÿ“ New York Weill Medical College of Cornell University ยท Tests: 225Ac-J591, Pembrolizumab, Androgen receptor inhibitor, 68Ga-PSMA-11 START-MET HS Prostate Cancer. : SbrT & Androgen Receptor Therapy METastatic HSPC NCT05209243NA2 sites๐Ÿ“ Madrid๐Ÿ“ Valencia Instituto de Investigaciรณn en Oncologรญa Radioterรกpica - Funโ€ฆ ยท Tests: SBRT, STANDARD OF CARE Evaluating Hormone Therapy to Achieve Optimal Doses in Metastatic Prostate Cancer NCT07751133Phase 32 sites๐Ÿ“ Manchester๐Ÿ“ Sutton University College, London ยท Tests: Abiraterone, Apalutamide, Enzalutamide or Darolutamide (ARPI therapy) (per standard of care) therapy Prostate Cryoablation Combined With Metronomic Cyclophosphamide for Metastatic Prostate Cancer NCT06854250Phase 21 site๐Ÿ“ Guangzhou Sun Yat-sen University ยท Tests: Prostate cryoablation, Cyclophosphamide (CTX) Clinical, Molecular and Imaging Biomarkers in Spinal and Bulbar Muscular Atrophy (SBMA) NCT04944940n/a1 site๐Ÿ“ Bethesda National Institute of Neurological Disorders and Stroke (NIโ€ฆ TulmiSTAR-02: A Phase I/II Open-label Study of Tulmimetostat in Combination With Darolutamide vs. Darolutamide, and Tulmimetostat With Abiraterone in Patients With Metastatic Hormone-sensitive Prostate Cancer (mHSPC) NCT07190300Phase 1, Phase 231 sites๐Ÿ“ Birmingham๐Ÿ“ Iowa City๐Ÿ“ Westwood Novartis Pharmaceuticals ยท Tests: Tulmimetostat, Darolutamide, Abiraterone, Prednisone/Prednisolone, Androgen Deprivation Therapy (ADT) ARCTIC: Liquid Biomarkers in the Prospective Androgen Receptor Signaling Inhibitors (ARSI) Resistance Clinical Trials NCT06141993n/a3 sites๐Ÿ“ New York๐Ÿ“ Durham๐Ÿ“ Madison Duke University ADT +/- Darolutamide in de Novo Metastatic Prostate Cancer Patients With Vulnerable Functional Ability (PEACE6-Vulnerable) NCT04916613Phase 395 sites๐Ÿ“ Charleroi๐Ÿ“ Haine-Saint-Paul๐Ÿ“ Namur UNICANCER ยท Tests: Darolutamide 300 mg, Placebo, Androgen deprivation therapy
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