🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

🧪

Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

Know your stage or your test results (such as EGFR, HER2 or BRCA)? Match trials to your own profile - nothing you type is saved.

🎯 Match trials to me

30 recruiting trials

for Squamous Cell Carcinoma Head and Neck Cancer (HNSCC)

Impact of Patient-Reported Outcomes for Symptom Monitoring in Patients Followed for Head and Neck Squamous Cell Carcinoma (HNSCC) NCT07190755NA2 sites📍 Rouen📍 Vandœuvre-lès-Nancy Centre Henri Becquerel · Tests: Remote symptoms moniotring 3-5 FrAction Stereotactic Body Radiation Therapy for Palliation of Head and Neck Squamous Cell Carcinoma: the FAST Phase II Randomized Trial NCT05674396Phase 21 site📍 Houston M.D. Anderson Cancer Center · Tests: Stereotactic body radiotherapy, Traditional Palliation A Study of PF-08046054/SGN-PDL1V in Advanced Solid Tumors NCT05208762Phase 162 sites📍 Birmingham📍 Birmingham📍 Birmingham Seagen, a wholly owned subsidiary of Pfizer · Tests: PF-08046054, pembrolizumab Anti-Ly6E Exatecan ADC M7437 in Advanced Solid Tumors NCT07360314Phase 19 sites📍 New Haven📍 Huntersville📍 Galveston EMD Serono Research & Development Institute, Inc. · Tests: M7437, M7437 Head and Neck Carcinoma Clinical Research Platform for Molecular and Blood-based Biomarkers, Treatment and Outcome NCT06380686n/a2 sites📍 Essen📍 Hanover AIO-Studien-gGmbH · Tests: data collection Immune Biomarker Study for Cisplatin-ineligible Patients Receiving Chemoradiotherapy With Docetaxel NCT06947668n/a1 site📍 Erlangen University of Erlangen-Nürnberg Medical School Collection of Plasma Samples for Squamous Cell Carcinoma of the Head and Neck Patients NCT02139020n/a5 sites📍 Ottignies📍 Charleroi📍 Haine-Saint-Paul Cliniques universitaires Saint-Luc- Université Catholique d… · Tests: Plasma samples EGFR/HER2 Dual-Target CAR-NK Cells for Recurrent or Metastatic HNSCC NCT07617805Phase 1, Phase 21 site📍 Shenzhen Beijing Biotech · Tests: EGFR/HER2 Dual-Target CAR-NK Cells, Fludarabine, Cyclophosphamide Multi-Site Trial of Navigation vs Treatment as Usual to Improve Initiation of Timely Adjuvant Therapy NCT05793151NA4 sites📍 St Louis📍 Durham📍 Charleston Medical University of South Carolina · Tests: ENDURE Nimotuzumab Combined With Immunotherapy and Chemotherapy in the Treatment of Locally Advanced Head and Neck Squamous Cell Carcinoma NCT07601737Phase 21 site📍 Shanghai Shanghai General Hospital, Shanghai Jiao Tong University Sc… · Tests: Nimotuzumab Injection, Tislelizumab, Albumin-Bound Paclitaxel /nab-Paclitaxel, Cisplatin (Or Carboplatin), Radical surg… Study Evaluating [18F]NOTA-ABY030 for Safety and Tolerability of Indeterminate Primary and/or Metastatic Disease in Head and Neck Squamous Cell Carcinoma NCT07217028Phase 11 site📍 Nashville Vanderbilt-Ingram Cancer Center · Tests: Cetuximab (EGFR inhibitor), 18F-NOTA-ABY-030, Positron Emission Tomography (PET) AK104 and Low-dose Radiation in Recurrent/Metastatic HNSCC After Failure of First-line Systemic Therapy NCT06494995Phase 21 site📍 Shanghai Fudan University · Tests: Cadonilimab, Low-dose radiotherapy, SBRT, Capecitabine Proactive Risk-based Optimization & Notifications for Treatment & Outcomes in Head & Neck Cancer NCT07180901NA1 site📍 Montreal Centre hospitalier de l'Université de Montréal (CHUM) · Tests: Proactive Risk-Based Optimization and Notifications for Treatment and Outcomes (PRONTO) Intralesional Chemotherapy (IC): Cisplatin + Epinephrine NCT07392580Phase 21 site📍 Miami University of Miami · Tests: Cisplatin, Epinephrine injection, Laryngeal Biopsy, Endoscopic Surgery A Study of DM005 in Patients With Advanced Solid Tumors NCT06515990Phase 1, Phase 26 sites📍 Detroit📍 Dallas📍 Fairfax Doma Biopharmaceutical（Suzhou）Co., Ltd. · Tests: DM005 A Study to Investigate the Safety, Pharmacokinetics, and Clinical Activity of AP203 in Patients with Locally Advanced or Metastatic Solid Tumors, and Expansion to Selected Malignancies NCT05473156Phase 1, Phase 21 site📍 Taipei AP Biosciences Inc. · Tests: AP203, AP203 Validity of Viome's Oral/throat Cancer Test NCT06174428n/a2 sites📍 St Louis📍 Memphis Viome · Tests: Oral/Throat cancer test First in Human Study of TUB-030 in Patients With Advanced Solid Tumors NCT06657222Phase 1, Phase 220 sites📍 New Haven📍 Miami📍 Boston Gilead Sciences · Tests: TUB-030 Effect of Postbiotics on Microbiota and Systemic Immunomodulation of Pembrolizumab as First-Line Therapy in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma (RM HNSCC) NCT07485296Phase 21 site📍 Rozzano Gruppo Oncologico del Nord-Ovest · Tests: Postbiotix-HLA™ is a food supplement based on fermented FOS from Lactobacillus paracasei CNCM I-5220 postbiotic., place… Impact of Early Response to First-line Anti-PD-1 Monotherapy in Patients With Recurrent and/or Metastatic (R/M) Head and Neck Squamous Cell Carcinoma, Assessed by 18F-FDG PET/CT NCT07448727n/a1 site📍 Rome University of Rome Tor Vergata Morning Versus Afternoon Administration of Immunotherapy for the Treatment of Advanced or Metastatic Solid Tumors, The Knight SHIFT Study NCT07405086Phase 41 site📍 Portland OHSU Knight Cancer Institute · Tests: Biospecimen Collection, Immune Checkpoint Inhibitor Prediction of Malignant Transformation of Oral Leukoplakia Using a MAGE-A-based Immunoscore NCT03975322n/a1 site📍 Erlangen University of Erlangen-Nürnberg Medical School A Study of the Use of Fat Flap Reconstruction to Reduce Neck Injury After Cancer Treatment NCT05889091NA1 site📍 New York Memorial Sloan Kettering Cancer Center · Tests: HRQOL instruments, LENT SOMA instrument A Study to Assess Adverse Events, Change in Disease Activity and Optimal Dose of Intravenous (IV) Telisotuzumab Adizutecan With IV Pembrolizumab for First-Line Treatment of Adult Participants With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma NCT07744126Phase 24 sites📍 Duarte📍 Newnan📍 Taichung AbbVie · Tests: Telisotuzumab Adizutecan, Pembrolizumab, Carboplatin, Cisplatin, Fluorouracil Study With ABBV-CLS-484 in Participants With Locally Advanced or Metastatic Tumors NCT04777994Phase 130 sites📍 Tucson📍 New Haven📍 Baltimore Calico Life Sciences LLC · Tests: ABBV-CLS-484, Vascular Endothelial Growth Factor Receptor (VEGFR) Tyrosine Kinase Inhibitor (TKI), Programmed Cell Deat… Towards Cure Via Only Ultra-short ICB in CSCC NCT06823479Phase 25 sites📍 Maastricht📍 Amsterdam📍 Amsterdam The Netherlands Cancer Institute · Tests: Nivolumab, Ipilumimab Evaluating Treatment Strategies for p53 Mutant Oral Cancer and Oral Cancer Precursors NCT07090070NA1 site📍 Vancouver University of British Columbia · Tests: Cohort 1 Intervention group, Cohort 2 severe/CIS margins clear, Cohort 2 p53 and severe/CIS margins clear, Cohort 3 Exc… A Dose Escalation and Dose Expansion Study of Intratumoral ONM-501 Alone and in Combination With Cemiplimab in Patients With Advanced Solid Tumors and Lymphomas. NCT06022029Phase 116 sites📍 Los Angeles📍 Tamarac📍 Canton OncoNano Medicine, Inc. · Tests: ONM-501, Cemiplimab Head and Neck Cancer Study Project in the Geriatric Population NCT06998069Phase 31 site📍 Providence Brown University · Tests: Arm I Carboplatin, Paclitaxel, Pembrolizumab, Arm II Carboplatin, Paclitaxel, Cetuximab, Arm III Pembrolizumab A Clinical Trial Comparing the Efficacy and Safety of Anyouping® and Platinum-based Chemotherapy With or Without Enlituo® in Advanced Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma. NCT07791745Phase 2, Phase 31 site📍 Shanghai Taizhou Mabtech Pharmaceutical Co.,Ltd · Tests: Enlituo® + Anyouping® + PBC, Placebo-Enlituo + Anyouping® + PBC
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy