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Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Squamous Cell Carcinoma of Oropharynx

Head and Neck Carcinoma Clinical Research Platform for Molecular and Blood-based Biomarkers, Treatment and Outcome NCT06380686n/a2 sites๐Ÿ“ Essen๐Ÿ“ Hanover AIO-Studien-gGmbH ยท Tests: data collection Immune Biomarker Study for Cisplatin-ineligible Patients Receiving Chemoradiotherapy With Docetaxel NCT06947668n/a1 site๐Ÿ“ Erlangen University of Erlangen-Nรผrnberg Medical School Multi-Site Trial of Navigation vs Treatment as Usual to Improve Initiation of Timely Adjuvant Therapy NCT05793151NA4 sites๐Ÿ“ St Louis๐Ÿ“ Durham๐Ÿ“ Charleston Medical University of South Carolina ยท Tests: ENDURE Testing the Addition of Ipatasertib to Usual Chemotherapy and Radiation for Head and Neck Cancer NCT05172245Phase 118 sites๐Ÿ“ Tampa๐Ÿ“ Chicago๐Ÿ“ Fairway National Cancer Institute (NCI) ยท Tests: Biopsy Procedure, Biospecimen Collection, Cisplatin, Computed Tomography, Ipatasertib Validity of Viome's Oral/throat Cancer Test NCT06174428n/a2 sites๐Ÿ“ St Louis๐Ÿ“ Memphis Viome ยท Tests: Oral/Throat cancer test Neoadjuvant Chemotherapy and Programmed Cell Death Protein 1(PD-1) Inhibition for Head and Neck Cancer Treatment De-escalation (NeoScorch HN) NCT07209189Phase 21 site๐Ÿ“ Baltimore Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins ยท Tests: Toripalimab + Chemotherapy, Toripalimab, Chemoradiotherapy or radiation TMV Vaccine Therapy Alone and With Pembrolizumab for the Treatment of Recurrent and/or Metastatic Head and Neck Squamous Cell Cancer NCT06868433Phase 12 sites๐Ÿ“ Atlanta๐Ÿ“ Atlanta Emory University ยท Tests: Autologous Tumor Membrane Vesicles Vaccine, Biospecimen Collection, Computed Tomography, Echocardiography, Magnetic Resโ€ฆ Reduced Elective Nodal and CTV Dose for HPV+ Oropharyngeal Squamous Cell Carcinoma NCT07497607Phase 21 site๐Ÿ“ Cincinnati Sara Medek ยท Tests: Cisplatin, Radiotherapy Study of De_Intensified Postoperative Radiation Therapy for HPV Associated Oropharyngeal Squamous Cell Carcinoma NCT03875716NA1 site๐Ÿ“ Boston Dana-Farber Cancer Institute ยท Tests: Radiation therapy Docetaxel and SX-682 in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma, Salivary Gland Carcinoma, and Advanced Prostate Cancer NCT07667400Phase 1, Phase 21 site๐Ÿ“ Bethesda National Cancer Institute (NCI) ยท Tests: SX-682, DTX De-escalation of Radiation Dose in HPV-associated OPC Utilising FMISO PET (DE-RADIATE) NCT06307015NA1 site๐Ÿ“ Saint Leonards Royal North Shore Hospital ยท Tests: De-escalation, Standard of care A Study to Evaluate CRB-701 Compared to Investigator's Choice Therapy in Previously Treated Oropharyngeal Squamous Cell Carcinoma NCT07768189Phase 3111 sites๐Ÿ“ Huntsville๐Ÿ“ Tucson๐Ÿ“ Duarte Corbus Pharmaceuticals Inc. ยท Tests: CRB-701, capcitabine, Cetuximab (EGFR inhibitor), Docetaxel A Study to Evaluate Lenti-HPV-07 Immunotherapy Against HPV+ Cervical or Oropharyngeal Cancer NCT06319963Phase 1, Phase 24 sites๐Ÿ“ Orlando๐Ÿ“ Tampa๐Ÿ“ Tampa Theravectys S.A. ยท Tests: Two IM injections Lenti-HPV-07, One IM injection Lenti-HPV-07 Selective Adjuvant Therapy for HPV-mediated Oropharynx SCCs Based on Residual Circulating Tumor DNA Levels (SAVAL) NCT06088381Phase 25 sites๐Ÿ“ Baltimore๐Ÿ“ Baltimore๐Ÿ“ Bel Air University of Maryland, Baltimore ยท Tests: Experimental Observation, Observation per Standard of Care, Adjuvant Treatment per Standard of Care, Circulating Tumor โ€ฆ Intranasal WSK-IM05 Vaccine Plus Tislelizumab as Neoadjuvant Therapy for HPV+ OPSCC NCT07565740Phase 11 site๐Ÿ“ Chengdu West China Hospital ยท Tests: WSK-IM05 (4ร—10^10 vp), WSK-IM05 (8ร—10^10 vp), WSK-IM05 (1.6x10^11 vp), Tislelizumab Thermotherapy for Head and Neck Cancer Patients NCT07690618Phase 11 site๐Ÿ“ Rotterdam Erasmus Medical Center ยท Tests: Thermotherapy, Radiotherapy, Concurrent chemoradiation Tissue Sample Collection From Patients With Head and Neck Cancer and From Healthy Participants NCT00898638n/a4 sites๐Ÿ“ Nashville๐Ÿ“ Nashville๐Ÿ“ Nashville Vanderbilt University Medical Center ยท Tests: biologic sample preservation procedure, medical chart review Testing the Addition of Chemotherapy or Chemo-Immunotherapy to the Usual Surgery for Advanced Head and Neck Cancer NCT07195734Phase 2115 sites๐Ÿ“ Tucson๐Ÿ“ Tucson๐Ÿ“ Irvine National Cancer Institute (NCI) ยท Tests: Biospecimen Collection, Carboplatin, Cemiplimab, Cisplatin, Computed Tomography The Registry Study of Genetic Alterations of Oropharyngeal Cancer in Taiwan NCT05522881n/a7 sites๐Ÿ“ Kaohsiung City๐Ÿ“ Kaohsiung City๐Ÿ“ Taichung National Health Research Institutes, Taiwan Human Papillomavirus Association and Genomic Exploration in Head-Neck Squamous Cell Carcinomas NCT06642324n/a1 site๐Ÿ“ Dhaka Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladโ€ฆ ยท Tests: Histopathology, Immunohistochemistry, Real-Time PCR, Sequencing Personalized Volume-deescalated Elective Nodal Irradiation in Oropharyngeal Head and Neck Squamous Cell Carcinoma NCT06563362Phase 27 sites๐Ÿ“ Zurich๐Ÿ“ Aarau๐Ÿ“ Bellinzona University of Zurich ยท Tests: De-escalation of irradiated volume Biomarkers in Patients With Respiratory Tract Dysplasia or Lung Cancer, Head and Neck Cancer, or Aerodigestive Tract Cancer and in Normal Volunteers NCT00900419n/a1 site๐Ÿ“ Aurora University of Colorado, Denver ยท Tests: immunohistochemistry staining method, laboratory biomarker analysis, sputum cytology, biopsy Enhancing Oral Cancer Awareness NCT06682494NA1 site๐Ÿ“ Richmond Virginia Commonwealth University ยท Tests: Traditional Education, AI-powered Chatbox CUE-101with Pembrolizumab for Locally Advanced HPV+HNSCCs NCT07172256Phase 21 site๐Ÿ“ New Haven Yale University ยท Tests: CUE-101, Pembrolizumab Prospective Assessment of HPV Associated Anogenital Pathology in Female Patients and Female Partners of Patients With Confirmed HPV Associated Oropharyngeal Carcinoma, PAP-OP Study NCT06115772n/a1 site๐Ÿ“ Rochester Mayo Clinic ยท Tests: Non-Interventional Study A Study Evaluating Ficerafusp Alfa (BCA101) QW in Combination With Pembrolizumab vs Alternative Ficerafusp Alfa Dosing in 1L R or M HNSCC NCT07807163Phase 27 sites๐Ÿ“ Fort Myers๐Ÿ“ Orlando๐Ÿ“ St. Petersburg Bicara Therapeutics ยท Tests: Ficerafusp alfa, Pembrolizumab (KEYTRUDAยฎ) Testing the Addition of the Drug BMX-001, a Radioprotector, or a Placebo to the Usual Chemoradiation Therapy for Patients With Head and Neck Cancer NCT06532279Phase 2153 sites๐Ÿ“ Gilbert๐Ÿ“ Peoria๐Ÿ“ Phoenix NRG Oncology ยท Tests: Best Practice, Biospecimen Collection, Cisplatin, Computed Tomography, Image Guided Radiation Therapy HPV DNA-Guided Radiotherapy De-intensification of Head and Neck Squamous Cell Carcinoma NCT05962242Phase 25 sites๐Ÿ“ Miami๐Ÿ“ Charlottesville๐Ÿ“ Norfolk University of Virginia ยท Tests: Radiation Therapy Afatinib in Patients With Fanconi Anemia (FA) and Advanced Head and Neck Squamous Cell Carcinoma (HNSCC) NCT06648096Phase 1, Phase 22 sites๐Ÿ“ Hanover๐Ÿ“ Barcelona Fundaciรณ Institut de Recerca de l'Hospital de la Santa Creuโ€ฆ ยท Tests: Afatinib Intratumoral Lidocaine Injection Before Oropharyngeal Cancer Surgery NCT06747390Phase 11 site๐Ÿ“ Philadelphia Ryan Carey ยท Tests: Lidocaine 1% Injectable Solution
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