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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Stage II Squamous Cell Carcinoma of the Head and Neck

3-5 FrAction Stereotactic Body Radiation Therapy for Palliation of Head and Neck Squamous Cell Carcinoma: the FAST Phase II Randomized Trial NCT05674396Phase 21 site📍 Houston M.D. Anderson Cancer Center · Tests: Stereotactic body radiotherapy, Traditional Palliation Immunotherapy in Combination With Chemoradiotherapy in Unresectable Locally Advanced Esophageal Cancer NCT06173986Phase 1, Phase 21 site📍 Shanghai Shanghai Chest Hospital · Tests: PD-1inhibitor, nab-paclitaxel + cisplatin, Radiotherapy Nimotuzumab Combined With Immunotherapy and Chemotherapy in the Treatment of Locally Advanced Head and Neck Squamous Cell Carcinoma NCT07601737Phase 21 site📍 Shanghai Shanghai General Hospital, Shanghai Jiao Tong University Sc… · Tests: Nimotuzumab Injection, Tislelizumab, Albumin-Bound Paclitaxel /nab-Paclitaxel, Cisplatin (Or Carboplatin), Radical surg… AK104 and Low-dose Radiation in Recurrent/Metastatic HNSCC After Failure of First-line Systemic Therapy NCT06494995Phase 21 site📍 Shanghai Fudan University · Tests: Cadonilimab, Low-dose radiotherapy, SBRT, Capecitabine Testing the Addition of Ipatasertib to Usual Chemotherapy and Radiation for Head and Neck Cancer NCT05172245Phase 118 sites📍 Tampa📍 Chicago📍 Fairway National Cancer Institute (NCI) · Tests: Biopsy Procedure, Biospecimen Collection, Cisplatin, Computed Tomography, Ipatasertib Effect of Postbiotics on Microbiota and Systemic Immunomodulation of Pembrolizumab as First-Line Therapy in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma (RM HNSCC) NCT07485296Phase 21 site📍 Rozzano Gruppo Oncologico del Nord-Ovest · Tests: Postbiotix-HLA™ is a food supplement based on fermented FOS from Lactobacillus paracasei CNCM I-5220 postbiotic., place… A Clinical Trial Comparing the Efficacy and Safety of Anyouping® and Platinum-based Chemotherapy With or Without Enlituo® in Advanced Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma. NCT07791745Phase 2, Phase 31 site📍 Shanghai Taizhou Mabtech Pharmaceutical Co.,Ltd · Tests: Enlituo® + Anyouping® + PBC, Placebo-Enlituo + Anyouping® + PBC A Phase II Trial to Evaluate the Effect of Itraconazole on Pathologic Complete Response Rates in Resectable Esophageal Cancer NCT05563766Phase 27 sites📍 Palo Alto📍 Ann Arbor📍 Durham VA Office of Research and Development · Tests: Itraconazole HN-BIO 02: A Phase II Randomized Study of the Effects of Delayed Elective Radiotherapy on Head and Neck MRI and Immune Response Biomarkers NCT06487403NA1 site📍 Toronto University Health Network, Toronto · Tests: Standard of care external beam radiotherapy (single integrated boost), Standard of care external beam radiotherapy (two… Docetaxel and SX-682 in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma, Salivary Gland Carcinoma, and Advanced Prostate Cancer NCT07667400Phase 1, Phase 21 site📍 Bethesda National Cancer Institute (NCI) · Tests: SX-682, DTX Sacituzumab Tirumotecan and Toripalimab in the First-line Treatment of HNSCC NCT07088211Phase 21 site📍 Shanghai Shanghai Ninth People's Hospital Affiliated to Shanghai Jia… · Tests: Sacituzumab Tirumotecan and Toripalimab Phase II Trial of Neoadjuvant and Adjuvant IO102-IO103 and Pembrolizumab KEYTRUDA® in Patients With Resectable Tumors NCT05280314Phase 215 sites📍 New Haven📍 Boston📍 Richmond IO Biotech · Tests: IO102-IO103, Pembrolizumab KEYTRUDA® Selective Adjuvant Therapy for HPV-mediated Oropharynx SCCs Based on Residual Circulating Tumor DNA Levels (SAVAL) NCT06088381Phase 25 sites📍 Baltimore📍 Baltimore📍 Bel Air University of Maryland, Baltimore · Tests: Experimental Observation, Observation per Standard of Care, Adjuvant Treatment per Standard of Care, Circulating Tumor … A Phase II Study to Evaluate the Efficacy and Safety of SKB571 in Recurrent or Metastatic HNSCC Participants NCT07668154Phase 22 sites📍 Chengdu📍 Shanghai Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. · Tests: SKB571, Pembrolizumab, carboplatin, Cisplatin RAPA-201 Therapy of Solid Tumors NCT05144698Phase 1, Phase 21 site📍 Hackensack Rapa Therapeutics LLC · Tests: RAPA-201 Rapamycin Resistant T Cells, Chemotherapy Prior to RAPA-201 Therapy, Pembrolizumab (PD-1 Blocking Antibody) Tissue Sample Collection From Patients With Head and Neck Cancer and From Healthy Participants NCT00898638n/a4 sites📍 Nashville📍 Nashville📍 Nashville Vanderbilt University Medical Center · Tests: biologic sample preservation procedure, medical chart review Intra-arterial Chemotherapy Combined with Radiotherapy and Immunotherapy for HNSCC NCT06725498Phase 21 site📍 Beijing Beijing Tongren Hospital · Tests: Tislelizumab-jsgr, Cisplatin, Albumin-Bound Paclitaxel, Radiotherapy Dalpicilib Plus Cetuximab Compared With Cetuximab Alone in HPV-negative, Anti-PD-1-resistant R/M HNSCC NCT06935188Phase 21 site📍 Shanghai Shanghai Ninth People's Hospital Affiliated to Shanghai Jia… · Tests: Dalpicilib combined with cetuximab, cetuximab Testing the Addition of Chemotherapy or Chemo-Immunotherapy to the Usual Surgery for Advanced Head and Neck Cancer NCT07195734Phase 2115 sites📍 Tucson📍 Tucson📍 Irvine National Cancer Institute (NCI) · Tests: Biospecimen Collection, Carboplatin, Cemiplimab, Cisplatin, Computed Tomography The Efficacy and Safety of De-escalated Postoperative Radiotherapy in Locally Advanced HNSCC With pCR/MPR NCT05854823NA1 site📍 Zhuhai Fifth Affiliated Hospital, Sun Yat-Sen University · Tests: dose-reduced radiotherapy KC1036 in Combination With PD-1 Antibody and Platinum-based Chemotherapy for First-line Advanced Esophageal Cancer NCT07481058Phase 21 site📍 Beijing Beijing Konruns Pharmaceutical Co., Ltd. · Tests: KC1036, Toripalimab, Paclitaxel, Cisplatin, KC1036 Window of Opportunity in Preserving Laryngeal Function Trial NCT07423078Phase 21 site📍 Pittsburgh Matthew Spector · Tests: Toripalimab, Carboplatin, Cisplatin, Paclitaxel, Radiation Therapy Candida Therapeutic Vaccine in Head and Neck Cancer Patients to Reduce Recurrence NCT05952934Phase 26 sites📍 Fayetteville📍 Little Rock📍 Rogers University of Arkansas · Tests: 0.5 mL Candin®/injection, Placebo: 0.5 mL Intravenous 0.9% NaCl solution (Saline) Clinical Trial of SIBP-03 in Patients With Head and Neck Squamous Cell Carcinoma NCT06194656Phase 22 sites📍 Shanghai📍 Shanghai Shanghai Institute Of Biological Products · Tests: HER3 Monoclonal antibodies-Dose A, HER3 Monoclonal antibodies-Dose B, HER3 Monoclonal antibodies-Dose C, HER3 Monoclona… A Phase I/II Trial of HCB101 in Combination With Pembrolizumab for Patients With Platinum-Refractory, Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma (SirH&N Trial) NCT07136545Phase 1, Phase 23 sites📍 Taoyuan📍 Taipei📍 Taipei Taipei Veterans General Hospital, Taiwan · Tests: HCB101, Pembrolizumab A Trial of SHR-A2102 With Adebrelimab With or Without Other Anti-tumor Therapies in Recurrent/MetastaticHead and Neck Squamous Cell Carcinoma Cancer NCT07059221Phase 1, Phase 22 sites📍 Chongqing📍 Chengdu Suzhou Suncadia Biopharmaceuticals Co., Ltd. · Tests: SHR-A2102, Adebrelimab, Cetuximab, SHR-9839(sc), Carboplatin / Cisplatin A Phase I/II Study of VLS-1488 in Subjects With Advanced Cancer NCT05902988Phase 1, Phase 214 sites📍 Los Angeles📍 Newport Beach📍 Aurora Volastra Therapeutics, Inc. · Tests: VLS-1488 Testing the Addition of the Drug BMX-001, a Radioprotector, or a Placebo to the Usual Chemoradiation Therapy for Patients With Head and Neck Cancer NCT06532279Phase 2153 sites📍 Gilbert📍 Peoria📍 Phoenix NRG Oncology · Tests: Best Practice, Biospecimen Collection, Cisplatin, Computed Tomography, Image Guided Radiation Therapy Study of Cetuximab Plus/Minus Weekly Paclitaxel After Progression To First-Line Pembrolizumab Plus Platinum-5FU in Subjects With Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck. NCT06856213Phase 217 sites📍 Santiago de Compostela📍 Badalona📍 Barcelona Grupo Español de Tratamiento de Tumores de Cabeza y Cuello · Tests: Cetuximab, Paclitaxel PPIO-008 Tislelizumab Combined With S-1 in Patients With ypT+N0 ESCC After Radical Resection With Neoadjuvant STUDY NCT06354140Phase 21 site📍 Chongqing Daping Hospital and the Research Institute of Surgery of th… · Tests: Tegafur
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