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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

Know your stage or your test results (such as EGFR, HER2 or BRCA)? Match trials to your own profile - nothing you type is saved.

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30 recruiting trials

for TCR-T Cells

Clinical Study on the EBV CAR-T /TCR-T Cells in the Treatment of Nasopharyngeal Carcinoma NCT05587543EARLY Phase 11 site๐Ÿ“ Shanghai Fudan University ยท Tests: PK Blood Collection, CAR, TCR Master Protocol of TCR-modified T Cell Therapy Targeting HLA-restricted KRAS Antigen Administered in Adult Patients With Metastatic or Locally Advanced PDAC NCT07145450Phase 1, Phase 210 sites๐Ÿ“ Copenhagen๐Ÿ“ Berlin๐Ÿ“ Dresden Anocca AB ยท Tests: ANOC-001 (TCR-T cells targeting KRAS G12V mutation presented by specific HLA alleles), ANOC-002 (TCR-T cells targeting โ€ฆ LANDscape MApping of Epitopes and T Cell Receptors for Selected Cancers NCT04665388n/a1 site๐Ÿ“ Toronto University Health Network, Toronto TCR Alpha Beta T-cell Depleted Haploidentical HCT in the Treatment of Non-Malignant Hematological Disorders in Children NCT04356469Phase 21 site๐Ÿ“ St. Petersburg Johns Hopkins All Children's Hospital ยท Tests: Haploidentical Hematopoietic Cell Transplantation Autologous T Cells Transduced With Retroviral Vectors Expressing TCRs for Participant-specific Neoantigens in Patients With Hematologic Malignancies NCT06904066Phase 11 site๐Ÿ“ Bethesda National Cancer Institute (NCI) ยท Tests: aldesleukin, cyclophosphamide, fludarabine phosphate, Individual Patient TCR-Transduced PBL, TruSight Oncology (TSO) 500 T Cell Receptor Gene-Engineered T Cell Therapy Targeting KRAS Mutations in the Treatment of Subjects With Advanced Solid Tumor NCT06484556Phase 12 sites๐Ÿ“ Wuhan๐Ÿ“ Wuhan Tao Zhang ยท Tests: NW-301V, NW-301D Blinatumomab After TCR Alpha Beta/CD19 Depleted HCT NCT04746209Phase 21 site๐Ÿ“ Milwaukee Medical College of Wisconsin ยท Tests: Alpha/Beta T-cell and B-cell depleted HCT, Blinatumomab MT2021-08T Cell Receptor Alpha/Beta Depletion PBSC Transplantation for Heme Malignancies NCT05735717Phase 21 site๐Ÿ“ Minneapolis Masonic Cancer Center, University of Minnesota ยท Tests: Fludarabine, Busulfan, Melphalan, Rituximab, Levetiracetam Stem Cell Transplant From Donors After Alpha Beta Cell Depletion in Children and Young Adults NCT04249830NA1 site๐Ÿ“ Palo Alto Alice Bertaina ยท Tests: Allogeneic Stem Cell Transplant, CliniMACS TCR ฮฑ/ฮฒ Reagent Kit and CliniMACS CD19 ACTengineยฎ IMA203/IMA203CD8 as Monotherapy or in Combination With Nivolumab in Recurrent and/or Refractory Solid Tumors NCT03686124Phase 1, Phase 221 sites๐Ÿ“ Stanford๐Ÿ“ Aurora๐Ÿ“ Miami Immatics US, Inc. ยท Tests: IMA203 Product, IMA203 product- flat dose, IMA203CD8 Product, Nivolumab, IMADetectยฎ KSH01-TCRT Solid Tumors NCT05539833EARLY Phase 11 site๐Ÿ“ Nanning TCRx Therapeutics Co.Ltd ยท Tests: KSH01 injection TCR-T Cell Immunotherapy of Lung Cancer and Other Solid Tumors NCT03778814Phase 11 site๐Ÿ“ Guanzhou Second Affiliated Hospital of Guangzhou Medical University ยท Tests: TCR-T cells HA-1 T TCR T Cell Immunotherapy for the Treatment of Patients With Relapsed or Refractory Acute Leukemia After Donor Stem Cell Transplant NCT03326921Phase 11 site๐Ÿ“ Seattle Fred Hutchinson Cancer Center ยท Tests: CD8+ and CD4+ Donor Memory T-cells-expressing HA1-Specific TCR, Bone Marrow Aspiration, Biospecimen Collection KSX01-TCRT Injection Project in Solid Tumors NCT05811975EARLY Phase 11 site๐Ÿ“ Nanning TCRx Therapeutics Co.Ltd ยท Tests: KSX01-TCRT injection Anti-NY-ESO-1 TCR-Gene Engineered Lymphocytes Given by Infusion to Patients With NY-ESO-1 -Expressing Metastatic Cancers NCT05296564Phase 1, Phase 21 site๐Ÿ“ Jerusalem Hadassah Medical Organization ยท Tests: CYCLOPHOSPHAMIDE and FLUDARABIN, Cyclophosphamide, HBI 0201-ESO TCRT, Aldesleukin TCR-engineered T Cells (NW-101C) in Patients With Solid Malignant Tumors NCT07266298Phase 11 site๐Ÿ“ Beijing Neowise Biotechnology ยท Tests: NW-101C Exploratory Study of EBV-TCR-T Cell Injection for EBV DNAemia After Allogeneic Hematopoietic Stem Cell Transplantation NCT07368634Phase 1, Phase 21 site๐Ÿ“ Beijing Daihong Liu ยท Tests: EBV-TCR-T Cell Injection MAGE-C2 TCR T Cell Trial to Treat Melanoma and Head and Neck Cancer NCT04729543Phase 1, Phase 21 site๐Ÿ“ Rotterdam Erasmus Medical Center ยท Tests: Adoptive therapy with autologous MC2 TCR T cells TCR Reserved and Power3 (SPPL3) Gene Knock-out Allogeneic CD19-targeting CAR-T Cell Therapy in r/r B-ALL NCT06481735Phase 1, Phase 26 sites๐Ÿ“ Beijing๐Ÿ“ Beijing๐Ÿ“ Beijing Chinese PLA General Hospital ยท Tests: TCR reserved and Power3 (SPPL3) Gene Knock-out Allogeneic CD19-targeting CAR-T cell, Fludarabine, Cyclophosphamide PSMA-Guided Surgery and Tissue-Resident T-Cell Profiling in Node-Positive Prostate Cancer NCT07879820NA1 site๐Ÿ“ Milan Niguarda Hospital ยท Tests: PSMA-Radioguided Robot-Assisted Radical Prostatectomy With Extended Pelvic Lymph-Node Dissection Administering Peripheral Blood Lymphocytes Transduced With a Murine T-Cell Receptor Recognizing the G12V Variant of Mutated RAS in HLA-A*11:01 Patients NCT03190941Phase 1, Phase 21 site๐Ÿ“ Bethesda National Cancer Institute (NCI) ยท Tests: Cyclophosphamide, Fludarabine, Anti-KRAS G12V mTCR PBL, Aldesleukin Autologous HBV-TCR T Cell Therapy (LioCyx-M) for the Treatment of Hepatocellular Carcinoma NCT06961617Phase 11 site๐Ÿ“ Beijing Lion TCR Pte. Ltd. ยท Tests: LioCyx-M, HBV antigen-specific TCR-redirected T cells A Study of Invikafusp Alfa (STAR0602), a Selective T Cell Receptor (TCR)-Targeting, Bifunctional Antibody-fusion Molecule, in Combination With Sacituzumab Govitecan in Participants With Advanced Solid Tumors NCT06827613Phase 1, Phase 28 sites๐Ÿ“ Los Angeles๐Ÿ“ Los Angeles๐Ÿ“ Boston Marengo Therapeutics, Inc. ยท Tests: STAR0602, Sacituzumab Govitecan (SG) Multi-center Study of TBI-1301 (INN: Mipetresgene Autoleucel; Mip-cel) in Patients With NY-ESO-1 Positive Synovial Sarcoma NCT07174427Phase 33 sites๐Ÿ“ Osaka๐Ÿ“ Fukuoka๐Ÿ“ Kashiwa Takara Bio Inc. ยท Tests: TBI-1301, Cyclophosphamide, Fludarabine Molecularly Redefining Small Bowel Adenocarcinoma to Accelerate Precision Patient Care NCT06234306n/a3 sites๐Ÿ“ Aarhus N๐Ÿ“ Copenhagen ร˜๐Ÿ“ Herlev Copenhagen University Hospital at Herlev A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors NCT05592626Phase 1, Phase 219 sites๐Ÿ“ Sacramento๐Ÿ“ Celebration๐Ÿ“ Miami Marengo Therapeutics, Inc. ยท Tests: STAR0602, Irinotecan (Camptosar), Docetaxel (Taxotere) FH-WT1-E50 TCR T Cells With Azacitidine for the Treatment of Minimal Residual Disease Positive Acute Myeloid Leukemia NCT07645469Phase 11 site๐Ÿ“ Seattle Fred Hutchinson Cancer Center ยท Tests: Autologous HLA-A*02:01-restricted CD4+/CD8+ Anti-WT1 TCR/CD8ab-expressing T-cells, Azacitidine, Biospecimen Collection,โ€ฆ Phase I/II Study of Engineered T Cell Receptor-Modified NK Cells Targeting PRAME in Conjunction With Lymphodepleting Chemotherapy for the Management of Relapse/Refractory Myeloid Malignancies NCT06383572Phase 1, Phase 21 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Cyclophosphamide, Fludarabine phosphate, Decitabine, Dexamethasone Study of QUAIL-100 in Pediatric and Young Adult Participants With High-Risk Hematologic Malignancies Who Have Received a Hematopoietic Stem Cell Transplantation NCT07573111Phase 11 site๐Ÿ“ Palo Alto Laguna Biotherapeutics, Inc. ยท Tests: QUAIL-100 Administration of Autologous T-Cells Genetically Engineered to Express T-Cell Receptors Reactive Against Neoantigens in People With Metastatic Cancer NCT03412877Phase 21 site๐Ÿ“ Bethesda National Cancer Institute (NCI) ยท Tests: Cyclophosphamide, Fludarabine, Aldesleukin, Individual Patient TCR-Transduced PBL, Pembrolizumab (KEYTRUDA(R))
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