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30 recruiting trials

for Transthyretin Cardiac Amyloidosis

Patisiran-Lipid Nanoparticle (LNP) Pregnancy Surveillance Program NCT05040373n/a7 sites๐Ÿ“ Iowa City๐Ÿ“ Nantes๐Ÿ“ Mรผnster Alnylam Pharmaceuticals Cardiac Magnetic Resonance and Echocardiography Study With Acoramidis NCT07695701Phase 41 site๐Ÿ“ St Louis Eidos Therapeutics, a BridgeBio company ยท Tests: Acoramidis (AG10) oral tablet Essen Amyloidosis Registry NCT06887283n/a1 site๐Ÿ“ Essen University Hospital, Essen A Study to Learn About the Use of Acoramidis in Patients With a Heart Condition Called Transthyretin Amyloid Cardiomyopathy (ATTR-CM) in a Real-world Setting NCT07235462n/a17 sites๐Ÿ“ Multiple Locations๐Ÿ“ Multiple Locations๐Ÿ“ Multiple Locations Bayer ยท Tests: Acoramidis (356 mg film-coated tablets) Genistein in trAnSthyretin recePtor Amyloid caRdiomyopathy NCT06634108Phase 1, Phase 21 site๐Ÿ“ London London Health Sciences Centre Research Institute OR Lawson โ€ฆ ยท Tests: Genistein Characterizing Iodine-124 Evuzumitide (AT-01) in Systemic Amyloidosis NCT05758493Phase 21 site๐Ÿ“ Portland Oregon Health and Science University ยท Tests: 124I-Evuzamitide ConTTRibute: A Global Observational Study of Patients With Transthyretin (TTR)-Mediated Amyloidosis (ATTR Amyloidosis) NCT04561518n/a40 sites๐Ÿ“ La Jolla๐Ÿ“ Los Angeles๐Ÿ“ Jacksonville Alnylam Pharmaceuticals An Interventional Pilot Study to Investigate the Feasibility and Acceptance of a Structured Psychological Support Program for Patients, Caregivers, and Presymptomatic Carriers in Hereditary Transthyretin Amyloidosis With Cardiomyopathy NCT06907186NA1 site๐Ÿ“ Pavia Fondazione IRCCS Policlinico San Matteo di Pavia ยท Tests: Psychological Support Non-interventional Study of Patients With Transthyretin (ATTR) Amyloidosis NCT06465810n/a89 sites๐Ÿ“ La Jolla๐Ÿ“ Los Angeles๐Ÿ“ San Francisco AstraZeneca ยท Tests: Treatment of transthyretin (ATTR) amyloidosis in observational study setting A Research Study to Look at the Distribution and Effects of Coramitug on Amyloid Deposits in Heart Tissue Using PET/CT Imaging in People With ATTR Amyloidosis. NCT07448623Phase 11 site๐Ÿ“ Groningen Novo Nordisk A/S ยท Tests: Coramitug Long-term Safety of Eplontersen Treated aTTR Patients and in Liver Transplant and Severely Hepatic Impaired Subpopulations NCT07654855n/a6 sites๐Ÿ“ Los Angeles๐Ÿ“ Vancouver๐Ÿ“ Beijing AstraZeneca ยท Tests: None ( observational study ) A Phase 3 Study of NTLA-2001 in ATTRv-PN NCT06672237Phase 314 sites๐Ÿ“ Buenos Aires๐Ÿ“ Buenos Aires๐Ÿ“ San Juan Bautista Intellia Therapeutics ยท Tests: nexiguran ziclumeran, Normal Saline as Placebo Quantitative-imaging in Cardiac Transthyretin Amyloidosis NCT05776212n/a1 site๐Ÿ“ Groningen University of Edinburgh ยท Tests: 18F-fluoride PET Exploratory Study Evaluating the Relevance of [68Ga]Ga-FAPI-46 for Staging and Identifying Progressing Patients With Transthyretin Cardiac Amyloidosis NCT07549841Phase 21 site๐Ÿ“ Nantes Nantes University Hospital ยท Tests: [68Ga]Ga-FAPI-46 Subclinical Transthyretin Cardiac Amyloidosis in V122I TTR Carriers NCT05489549n/a3 sites๐Ÿ“ New York๐Ÿ“ Cleveland๐Ÿ“ Dallas University of Texas Southwestern Medical Center Phenotypic Manifestations of Hereditary ATTR Amyloidosis NCT07124377n/a2 sites๐Ÿ“ Charata๐Ÿ“ Charata Hospital 9 de Julio de Las Breรฑas ยท Tests: A complete physical examination of all body systems, including height and body weight, Neurological examination includeโ€ฆ US Benchmarking Clinical Study NCT07215715n/a3 sites๐Ÿ“ Boston๐Ÿ“ Boston๐Ÿ“ Boston eMyosound SAS The Italian Transthyretin Amyloidosis Web-Network NCT05444920n/a30 sites๐Ÿ“ Legnano๐Ÿ“ Orbassano๐Ÿ“ Ancona Fondazione IRCCS Policlinico San Matteo di Pavia Multimodality Cardiac Imaging for Disease Progression in ATTR-CM NCT07112066NA1 site๐Ÿ“ Zurich Dominik Benz ยท Tests: FAPI tracer Study of Acoramidis in Patients With Transthyretin Amyloid Cardiomyopathy NCT07791160n/a1 site๐Ÿ“ Many Locations Bayer ยท Tests: Acoramidis Comprehensive Program for Hereditary Transthyretin Amyloidosis NCT07213297n/a1 site๐Ÿ“ Canuelas Hospital de Alta Complejidad en Red ยท Tests: clinical assessments and complementary examinations TRITON-PN: A Study to Evaluate the Efficacy and Safety of Nucresiran in Patients With Hereditary Transthyretin Amyloidosis With Polyneuropathy NCT07223203Phase 361 sites๐Ÿ“ Aurora๐Ÿ“ Chicago๐Ÿ“ Baltimore Alnylam Pharmaceuticals ยท Tests: Nucresiran, Vutrisiran Prevalence of Wild-type TTR Cardiac Amyloidosis in Patients With Polyneuropathy of Unknown Cause. NCT05950867NA1 site๐Ÿ“ Jette Universitair Ziekenhuis Brussel ยท Tests: ECG + echocardiography, Answering questionnaires Exercise Training in Transthyretin Cardiac Amyloidosis NCT05797857NA1 site๐Ÿ“ Boston Brigham and Women's Hospital ยท Tests: Exercise Training The Eplontersen Pregnancy and Lactation Outcomes Study NCT07205666n/a1 site๐Ÿ“ Frankfurt AstraZeneca NatiOnal Referral cenTEr Study of Transthyretin Amyloid Cardiomyopathy(ATTR) Patients on Tafamidis NCT06251778n/a1 site๐Ÿ“ Pavia Paolo Milani MAGNITUDE: A Phase 3 Study of NTLA-2001 in Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR-CM) NCT06128629Phase 3132 sites๐Ÿ“ Tucson๐Ÿ“ Los Angeles๐Ÿ“ Los Angeles Intellia Therapeutics ยท Tests: NTLA-2001, Placebo Quantitative Analysis of Myocardial Uptake of Bone Radiopharmaceuticals in Patients With Cardiac ATTR Amyloidosis NCT04535349NA2 sites๐Ÿ“ Caen๐Ÿ“ Lille University Hospital, Caen ยท Tests: Whole-body & CZT bone tracer imaging (SPECT) Efficacy and Safety of Intravenous YOLT-201 for Transthyretin Amyloidosis Cardiomyopathy NCT06082050EARLY Phase 11 site๐Ÿ“ Hangzhou Zhejiang University ยท Tests: YOLT-201 Thailand ATTR-CM Registry NCT06338696n/a8 sites๐Ÿ“ Bangkok๐Ÿ“ Bangkok๐Ÿ“ Bangkok Mahidol University ยท Tests: No intervention
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