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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Unresectable Hepatocellular Carcinoma

Triple Therapy Sequential Radiotherapy in Unresectable HCC (TALENP003) NCT06561399n/a4 sites📍 Fuzhou📍 Fuzhou📍 Fuzhou Fujian Provincial Hospital · Tests: TACE, Lenvatinib combination with Sintilimab sequential radiotherapy Dual-Target GPC3/B7-H3 CAR-NK Cells for Advanced HCC NCT07500220Phase 1, Phase 21 site📍 Shenzhen Beijing Biotech · Tests: EB-G3B7-NK dual-target CAR-NK cells, Fludarabine, Cyclophosphamide Lenvatinib+Sintilimab+TACE vs. Lenvatinib+TACE for Advanced HCC NCT05608200Phase 31 site📍 Guangzhou Second Affiliated Hospital of Guangzhou Medical University · Tests: Lenvatinib, sintilimab plus TACE, Lenvatinib plus TACE Dalpiciclib Plus Camrelizumab for HCC Patients Who Have Previously Received ICI Treatment NCT07238881Phase 21 site📍 Guangzhou Sun Yat-sen University · Tests: Dalpiciclib Isetionate Tablets, Dalpiciclib Isetionate Tablets, Camrelizumab (anti-PD-1 inhibitor) Tislelizumab Combined With Huaier Granule as First-line Treatment for Unresectable Hepatocellular Carcinoma NCT07413354Phase 21 site📍 Wuhan Tongji Hospital · Tests: Tislelizumab plus Huaier granule Modified Immune Cells (Autologous Dendritic Cells) and a Vaccine (Prevnar) Combined With Immune Checkpoint Inhibition After High-Dose External Beam Radiation Therapy in Treating Patients With Unresectable Liver Cancer NCT03942328Phase 1, Phase 21 site📍 Rochester Mayo Clinic · Tests: Atezolizumab, Bevacizumab, External Beam Radiation Therapy, Pheresis, Pneumococcal 13-valent Conjugate Vaccine TACE Combined With Immune Checkpoint Inhibitors for Liver Malignant Tumors NCT06487663NA1 site📍 Tianjin Tianjin Medical University Cancer Institute and Hospital · Tests: TACE with ICI IRE After Targeted Immunotherapy in HCC With Portal Vein Tumor Thrombus NCT07799922NA1 site📍 Tianjin Tianjin Medical University Cancer Institute and Hospital · Tests: IRE, PLACEBO Novel Subtypes and Treatment Strategies of Patients with Unresectable Combined Hepatocellular Cholangiocarcinoma Based on Multimodal Data NCT06849180n/a1 site📍 Nanjing Zhongda Hospital · Tests: Interventional therapies combined with or without systemic drugs Evaluation of the Interest to Combine a CD4 Th1-inducer Cancer Vaccine Derived From Telomerase and Atezolizumab Plus Bevacizumab in Unresectable Hepatocellular Carcinoma NCT05528952Phase 214 sites📍 Besançon📍 Chalon-sur-Saône📍 Créteil Centre Hospitalier Universitaire de Besancon · Tests: Atezolizumab, Bevacizumab, UCPVax Anti-PD-1/PD-L1 Combined With Anti-angiogenic Agents as First-line Treatment for Unresectable HCC NCT06360042Phase 21 site📍 Beijing Peking University Cancer Hospital & Institute · Tests: Adebrelimab plus Apatinib, Adebrelimab plus Bevacizumab, Camrelizumab plus Apatinib A Phase I Dose Escalation and Dose Expansion Study to Investigate the Pharmacokinetics and Safety of Subcutaneous Durvalumab NCT07391670Phase 119 sites📍 Fitzroy📍 St Albans📍 Woolloongabba AstraZeneca · Tests: SC durvalumab + rHu, IV durvalumab, Tremelimumab Prospective Collection of Therapeutic Efficacy and Safety Data in Patients with Unresectable Hepatocellular Carcinoma NCT06788353n/a1 site📍 Guangzhou Sun Yat-sen University Visugromab, Nivolumab and Lenvatinib Compared to Double Placebo and Lenvatinib in Unresectable or Metastatic Hepatocellular Carcinoma Post Anti-PD-(L)1 Failure NCT07219459Phase 223 sites📍 Irvine📍 Los Angeles📍 Orange CatalYm GmbH · Tests: Visugromab RDE (recommended dose for expansion), Nivolumab, Lenvatinib, Placebo Saline Infusion BioPearl™ Microspheres Loaded With Doxorubicin for the Treatment of Unresectable Hepatocellular Carcinoma (HCC) NCT05911633NA10 sites📍 Brussels📍 Leuven📍 Clichy Terumo Europe N.V. · Tests: BioPearl™ MDN-001 Injection for the Treatment of Unresectable Primary Hepatocellular Carcinoma. NCT07391839Phase 18 sites📍 Hefei📍 Fuzhou📍 Guangzhou Suzhou Mednovo Yi Medical Technology Co., Ltd. · Tests: MDN-001 Injection(Yttrium-90 Microsphere Injection) FGF19 Overexpression Combination Unified Study in HCC-19 NCT06978933Phase 21 site📍 Shanghai RenJi Hospital · Tests: ABSK-011 The Impact of Emotional Stress on Immunotherapy Outcomes in Liver Cancer Patients: A Multi-Cohort Study NCT07141056n/a5 sites📍 Zhanjiang📍 Guilin📍 Guilin Guilin Medical University, China · Tests: Psychological Stress Status, Psychological Stress Status, Psychological stress status Observational Study Protocol: LIVER-R NCT06252753n/a160 sites📍 Birmingham📍 Mobile📍 Phoenix AstraZeneca · Tests: Durvalumab-based combination therapies in observational study setting, Durvalumab-based combination therapies in observ… Cadonilimab and Lenvatinib for Conversion Therapy in Unresectable Hepatocellular Carcinoma NCT06215651Phase 21 site📍 Beijing Peking Union Medical College Hospital · Tests: Cadonilimab lenvatinib A Study of SHR-2524 Plus Bevacizumab in the First-line Treatment of Advanced Hepatocellular Carcinoma NCT07478302Phase 12 sites📍 Fuzhou📍 Nanning Suzhou Suncadia Biopharmaceuticals Co., Ltd. · Tests: SHR-2524 Injection, Bevacizumab Injection Atezolizumab Plus Bevacizumab Alone or Combined with External Beam Radiotherapy for HCC with Macrovascular Invasion NCT05992220Phase 21 site📍 Seoul Asan Medical Center · Tests: Atezolizumab plus bevacizumab, combined EBRT to vascular invasion, Atezolizumab plus bevacizumab Safety and Preliminary Anti-Tumor Activity of TYRA-430 in Advanced Hepatocellular Carcinoma and Other Solid Tumors With Activating FGF/FGFR Pathway Aberrations NCT06915753Phase 116 sites📍 Los Angeles📍 San Francisco📍 Stanford Tyra Biosciences, Inc · Tests: TYRA-430 Biomarker-Guided Dual-Target CAR-T Cells for Advanced Solid Tumors NCT07523529Phase 1, Phase 21 site📍 Shenzhen Beijing Biotech · Tests: Autologous dual-target CAR-T cells selected from the predefined target library., Fludarabine, Cyclophosphamide Adaptive Dosing of Immune Checkpoint Inhibitors for Hepatocellular Carcinoma NCT07689175Phase 21 site📍 Dallas University of Texas Southwestern Medical Center · Tests: Nivolumab, Ipilimumab (3 mg/kg) mFOLFOX7 Plus Camrelizumab and Apatinib in BCLC Stage A/B Hepatocellular Carcinoma Patients Beyond Milan Criteria NCT06607107Phase 21 site📍 Guangzhou Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University · Tests: mFOLFOX7 combined with Camrelizumab and apatinib Sintilimab+Bevacizumab+TACE vs. Lenvatinib+TACE for Advanced HCC NCT05985798Phase 31 site📍 Guangzhou Second Affiliated Hospital of Guangzhou Medical University · Tests: Sin-Bev-TACE, Len-TACE Ipilimumab N01 Combined With Sintilimab, Bevacizumab Biosimilar, and Hepatic Arterial Infusion Chemotherapy as Conversion Therapy for Unresectable Intermediate-Advanced Hepatocellular Carcinoma NCT07560488Phase 21 site📍 Tianjin Tianjin Medical University Cancer Institute and Hospital · Tests: Bevacizumab Biosimilar IBI305, ipilimumab N01, Sintilimab, HAIC Efficacy and Safety of Multimodal Ablation Combined With PD-1 Monoclonal Antibody, Lenvatinib and TACE in the Treatment of Unresectable Primary Hepatocellular Carcinoma: A Single-Arm, Single-Center Clinical Study NCT06794073NA1 site📍 Shanghai Shanghai Zhongshan Hospital · Tests: Multimodal Thermal Therapy SIRT for Potentially Resectable HCC NCT05994859NA1 site📍 Guangzhou Second Affiliated Hospital of Guangzhou Medical University · Tests: SIRT
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