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Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Upper Tract Urothelial Cancer

Pembrolizumab and Enfortumab Vedotin With Pembrolizumab Prior to and After Radical Nephroureterectomy for High-Risk Upper Tract Urothelial Cancer NCT05775471Phase 21 site📍 Los Angeles Jonsson Comprehensive Cancer Center · Tests: Biopsy, Biospecimen Collection, Enfortumab Vedotin, MR Urography, Nephroureterectomy A Phase 3 Single-arm Study of UGN-104 for the Treatment of Low-grade Upper Tract Urothelial Cancer NCT06774131Phase 379 sites📍 Homewood📍 Chandler📍 Queen Creek UroGen Pharma Ltd. · Tests: UGN-104 Study of Neoadjuvant Enfortumab Vedotin and Pembrolizumab in Upper Tract Urothelial Cancer NCT06356155Phase 22 sites📍 Ann Arbor📍 Philadelphia University of Michigan Rogel Cancer Center · Tests: Enfortumab vedotin, Pembrolizumab Radiotherapy Combined with Systemic Therapy Versus Systemic Therapy for Oligometastatic UTUCs NCT06652022NA2 sites📍 Beijing📍 Beijing Peking University First Hospital · Tests: Systematic therapy combined with radiotherapy, Systematic drug treatment Nephroureterectomy With and Without Lymph Node Dissection for Upper Tract Urothelial Cell Carcinoma NCT06262516NA4 sites📍 Gainesville📍 Springfield📍 Cleveland Case Comprehensive Cancer Center · Tests: Nephroureterectomy, Lymph Node Dissection Urinary Cell-Free DNA Liquid Biopsy for Urothelial Cancer Diagnosis and Origin Identification NCT07888374n/a1 site📍 Shanghai Ruijin Hospital Enfortumab Vedotin and Pembrolizumab With Cystectomy and/or Ureterectomy for Locally Advanced or Metastatic Bladder and Upper Urothelial Tract Cancer, CAST-AI Trial NCT06764095Phase 41 site📍 Rochester Mayo Clinic · Tests: Biospecimen Collection, Computed Tomography, Cystectomy, Enfortumab Vedotin, Local Therapy Korean Prospective Upper Tract Urothelial Carcinoma Cohort NCT07452432n/a1 site📍 Seoul Samsung Medical Center · Tests: Peripheral blood collection for ctDNA analysis Prospective Validation Study of High Volume Urine DNA Testing in Individuals With Suspicion of Urothelial Cancer NCT06310759n/a8 sites📍 Chicago📍 Vancouver📍 Helsinki Tampere University Hospital Testing the Addition of MEDI4736 (Durvalumab) to Chemotherapy Before Surgery for Patients With High-Grade Upper Urinary Tract Cancer NCT04628767Phase 2, Phase 3258 sites📍 Kingman📍 Fort Smith📍 Little Rock National Cancer Institute (NCI) · Tests: Biopsy Procedure, Biospecimen Collection, Cisplatin, Computed Tomography, Doxorubicin Hydrochloride Multicenter Clinical Trial of ST-02 for Ablation of Upper Tract Urothelial Carcinoma NCT06124976Phase 2, Phase 38 sites📍 Vancouver📍 Winnipeg📍 Halifax Peter Black · Tests: ST-02 Research of Double-positive Circulating Cells (Tumor Marker / CD45+) in Several Types of Metastatic Cancers NCT06967961NA1 site📍 Toulouse Institut Claudius Regaud · Tests: For each enrolled patient, the sample described below will be collected as specific intervention intended for research … The Danish Bladder Cancer Group 23 Study - A European Study on Cancer in the Upper Urinary Tract NCT07077447n/a5 sites📍 Aarhus N📍 Herlev📍 København Ø Zealand University Hospital · Tests: Kidney sparing surgery for high-risk upper urinary tract urothelial carcinoma DDR Genes Alteration and Response to Platinum-based Chemotherapy in Advanced Urothelial Cancer. NCT06820255Phase 41 site📍 Rome Fondazione Policlinico Universitario Agostino Gemelli IRCCS · Tests: Platinum + Gemcitabine, Avelumab first-line maintenance, NGS test for DDR alterations Combined Postoperative Radiotherapy With Kidney Sparing Surgery for Locally Advanced High-risk Ureteral Cancer NCT06120387n/a2 sites📍 Beijing📍 Beijing Xuesong Li · Tests: Radical surgery, Kidney sparing surgery+Postoperative radiotheray A Home-Based Prehabilitation Exercise Intervention for Improving Physical Function in Patients With Bladder Cancer and Upper Tract Urothelial Cancer, Get Moving Trial NCT06040762NA1 site📍 Seattle University of Washington · Tests: Best Practice, Exercise Intervention, App-Based Intervention, App-Based Intervention, Interview Translational Cancer Observational Protocol NCT06169436n/a1 site📍 Milan IRCCS San Raffaele · Tests: Nephroureterectomy Non-invasive Urinary Genomics-Based Risk Assessment for Early Urothelial Carcinoma Diagnosis NCT07614594n/a1 site📍 Zhengzhou Henan Provincial People's Hospital Renal Retention in High Grade Upper Tract Urothelial Cancer NCT05656235Phase 22 sites📍 Washington D.C.📍 Baltimore Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins · Tests: Enfortumab vedotin, Pembrolizumab uTRACT Jelmyto Registry: A Registry of Patients With Upper Tract Urothelial Cancer (UTUC) Treated With Jelmyto NCT05874921n/a22 sites📍 Santa Monica📍 Gainesville📍 Miami UroGen Pharma Ltd. · Tests: Jelmyto (mitomycin) for pyelocalyceal solution Radical Radiotherapy Versus Radical Surgery for UTUC NCT06652009n/a2 sites📍 Beijing📍 Beijing Peking University First Hospital · Tests: Radical nephroureterectomy, Radical radiotherapy SeqUential GeMcitabine and MITomycin Treatment for Favorable High-Risk Upper Urinary Tract Urothelial Carcinoma NCT06822010Phase 21 site📍 New Brunswick Rutgers, The State University of New Jersey · Tests: Sequential Gemcitabine and Jelmyto Treatment (Gem/Jel) Urothelial Cancer Screening in Individuals With Lynch Syndrome Using a Urine Tumor DNA Panel (LS-URO Study) NCT06218433NA2 sites📍 Vancouver📍 Tampere Tampere University Hospital · Tests: Urothelial cancer screening using urine tumor DNA test, Urothelial cancer screening using urine cytology (comparator) Circulating and Urine Tumor DNA Dynamics Predict Minimal Residual Disease and Recurrence Risk in Locally Advanced Upper Tract Urothelial Carcinoma NCT05595408n/a1 site📍 Shanghai RenJi Hospital · Tests: Adjuvant chemotherapy, adjuvant immunotherapy Specimen Collection for Validation of UroAmp: A Next Generation Sequencing Platform for Detection and Surveillance of Bladder Cancer NCT07673016n/a23 sites📍 Oceanside📍 San Diego📍 San Jose Convergent Genomics, Inc. Liquid Biospy for Urinary Cancers NCT06116396n/a1 site📍 Milan IRCCS San Raffaele · Tests: Genetic analysis on isolated cells Radical Nephroureterectomy With vs Without Template Lymph Node Dissection in High-Risk Upper Tract Urothelial Carcinoma (T-LND UTUC) NCT07321210NA1 site📍 Tianjin Tianjin Medical University Second Hospital · Tests: Template Lymph Node Dissection, Selective Lymph Node Resection Neoadjuvant Upper Tract Invasive Cancer Trial (NAUTICAL) NCT04574960Phase 32 sites📍 Ottawa📍 Toronto University Health Network, Toronto · Tests: Gemcitabine, Cisplatin, Carboplatin A Study of RC48-ADC Combined with JS001 for Postoperative Adjuvant Treatment of Upper Tract Urothelial Carcinoma NCT05917158Phase 21 site📍 Nanjing Jinling Hospital, China · Tests: RC48-ADC and JS001 Photodynamic Diagnosis of Upper Tract Urothelial Carcinoma Using Fluorescence Endoscopy and Oral 5-ALA NCT06948552Phase 21 site📍 Detroit Henry Ford Health System · Tests: 5-Aminolevulinic acid Hydrochloride (Gliolan®)
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