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Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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26 recruiting trials

for Upper Urinary Tract Urothelial Carcinoma

Pembrolizumab and Enfortumab Vedotin With Pembrolizumab Prior to and After Radical Nephroureterectomy for High-Risk Upper Tract Urothelial Cancer NCT05775471Phase 21 site📍 Los Angeles Jonsson Comprehensive Cancer Center · Tests: Biopsy, Biospecimen Collection, Enfortumab Vedotin, MR Urography, Nephroureterectomy A Phase 3 Single-arm Study of UGN-104 for the Treatment of Low-grade Upper Tract Urothelial Cancer NCT06774131Phase 379 sites📍 Homewood📍 Chandler📍 Queen Creek UroGen Pharma Ltd. · Tests: UGN-104 Urinary Cell-Free DNA Liquid Biopsy for Urothelial Cancer Diagnosis and Origin Identification NCT07888374n/a1 site📍 Shanghai Ruijin Hospital Enfortumab Vedotin and Pembrolizumab With Cystectomy and/or Ureterectomy for Locally Advanced or Metastatic Bladder and Upper Urothelial Tract Cancer, CAST-AI Trial NCT06764095Phase 41 site📍 Rochester Mayo Clinic · Tests: Biospecimen Collection, Computed Tomography, Cystectomy, Enfortumab Vedotin, Local Therapy Prospective Validation Study of High Volume Urine DNA Testing in Individuals With Suspicion of Urothelial Cancer NCT06310759n/a8 sites📍 Chicago📍 Vancouver📍 Helsinki Tampere University Hospital Office-Based Ureteroscopy Utilizing a Single Use Digital, Flexible Ureteroscope for Upper Tract Urothelial Carcinoma NCT07630155NA1 site📍 Ann Arbor University of Michigan Rogel Cancer Center · Tests: Analgesic Agent, Electronic Health Record Review, Lidocaine Topical, Medical Device Usage and Evaluation, Survey Admini… Testing the Addition of MEDI4736 (Durvalumab) to Chemotherapy Before Surgery for Patients With High-Grade Upper Urinary Tract Cancer NCT04628767Phase 2, Phase 3258 sites📍 Kingman📍 Fort Smith📍 Little Rock National Cancer Institute (NCI) · Tests: Biopsy Procedure, Biospecimen Collection, Cisplatin, Computed Tomography, Doxorubicin Hydrochloride Multicenter Clinical Trial of ST-02 for Ablation of Upper Tract Urothelial Carcinoma NCT06124976Phase 2, Phase 38 sites📍 Vancouver📍 Winnipeg📍 Halifax Peter Black · Tests: ST-02 A Clinical Study of the Efficacy and Safety of Disitamab Vedotin in Combination With Radiotherapy for the Adjuvant Treatment of HER2 Overexpressing UTUC Patients With High Risk Factors for Recurrence After Radical Surgery NCT06210490Phase 21 site📍 Beijing Peking University First Hospital · Tests: Disitamab Vedotin, Radiotherapy, Standard of Care Collecting and Studying Blood and Tissue Samples From Patients With Locally Recurrent or Metastatic Prostate or Bladder/Urothelial Cancer NCT01050504n/a1 site📍 Seattle University of Washington · Tests: Cytology Specimen Collection Procedure, Laboratory Biomarker Analysis The Danish Bladder Cancer Group 23 Study - A European Study on Cancer in the Upper Urinary Tract NCT07077447n/a5 sites📍 Aarhus N📍 Herlev📍 København Ø Zealand University Hospital · Tests: Kidney sparing surgery for high-risk upper urinary tract urothelial carcinoma Combination of DV and Tislelizumab for Renal Preservation in High-risk UTUC Patients NCT05912816Phase 21 site📍 Shanghai RenJi Hospital · Tests: RC48 Combined With Tislelizumab A Home-Based Prehabilitation Exercise Intervention for Improving Physical Function in Patients With Bladder Cancer and Upper Tract Urothelial Cancer, Get Moving Trial NCT06040762NA1 site📍 Seattle University of Washington · Tests: Best Practice, Exercise Intervention, App-Based Intervention, App-Based Intervention, Interview Translational Cancer Observational Protocol NCT06169436n/a1 site📍 Milan IRCCS San Raffaele · Tests: Nephroureterectomy Non-invasive Urinary Genomics-Based Risk Assessment for Early Urothelial Carcinoma Diagnosis NCT07614594n/a1 site📍 Zhengzhou Henan Provincial People's Hospital Renal Retention in High Grade Upper Tract Urothelial Cancer NCT05656235Phase 22 sites📍 Washington D.C.📍 Baltimore Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins · Tests: Enfortumab vedotin, Pembrolizumab Therapeutic Plasma Exchange With Enfortumab Vedotin and Pembrolizumab for Treatment of Bladder Cancers NCT07087860Phase 21 site📍 Rochester Mayo Clinic · Tests: Best Practice, Biospecimen Collection, Central Venous Cannula Insertion, Computed Tomography, Enfortumab Vedotin SeqUential GeMcitabine and MITomycin Treatment for Favorable High-Risk Upper Urinary Tract Urothelial Carcinoma NCT06822010Phase 21 site📍 New Brunswick Rutgers, The State University of New Jersey · Tests: Sequential Gemcitabine and Jelmyto Treatment (Gem/Jel) DV Combined With Toripalimab for Renal Preservation in Solitary Kidney or Renal Insufficiency or Bilateral Multiple UTUC NCT06354231Phase 21 site📍 Shanghai Fudan University · Tests: DV, Toripalimab, Laser surgery Urothelial Cancer Screening in Individuals With Lynch Syndrome Using a Urine Tumor DNA Panel (LS-URO Study) NCT06218433NA2 sites📍 Vancouver📍 Tampere Tampere University Hospital · Tests: Urothelial cancer screening using urine tumor DNA test, Urothelial cancer screening using urine cytology (comparator) Specimen Collection for Validation of UroAmp: A Next Generation Sequencing Platform for Detection and Surveillance of Bladder Cancer NCT07673016n/a23 sites📍 Oceanside📍 San Diego📍 San Jose Convergent Genomics, Inc. Liquid Biospy for Urinary Cancers NCT06116396n/a1 site📍 Milan IRCCS San Raffaele · Tests: Genetic analysis on isolated cells Neoadjuvant Upper Tract Invasive Cancer Trial (NAUTICAL) NCT04574960Phase 32 sites📍 Ottawa📍 Toronto University Health Network, Toronto · Tests: Gemcitabine, Cisplatin, Carboplatin Photodynamic Diagnosis of Upper Tract Urothelial Carcinoma Using Fluorescence Endoscopy and Oral 5-ALA NCT06948552Phase 21 site📍 Detroit Henry Ford Health System · Tests: 5-Aminolevulinic acid Hydrochloride (Gliolan®) Dual-Target Nectin-4/HER2 CAR-NK Cells in Advanced Urothelial Carcinoma NCT07492628Phase 11 site📍 Shenzhen Beijing Biotech · Tests: EB-DT-NK-UC101, Cyclophosphamide, Fludarabine A Multicenter Prospective Cohort Study on Monitoring Recurrence of Urothelial Carcinoma Based on Detection of Urinary Microscopic Residual Disease (MRD) NCT06991868n/a1 site📍 Beijing Peking University First Hospital
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