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Host Response to Infection and Treatment in Filarial Diseases

Recruitingn/aAges 3 Years - 100 YearsAllNational Institute of Allergy and Infectious Dise…
NCT00001230 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study will evaluate and treat patients with filarial infections to explore in depth the immunology of the disease, including susceptibility to infection, disease development, and response to treatment. Filarial infections are caused by parasitic worms. The immature worm (larva) is transmitted to a person through a mosquito bite and grows in the human body to 2 to 4 inches in length. Although many of these infections do not produce symptoms, especially in the early stages of infection, others can have serious consequences, including swelling of the limbs or genitalia, allergic-lung problems, skin rash, eye inflammation that can lead to blindness, and heart disease. This protocol does not involve any experimental diagnostic procedures or treatments, and will use only procedures employed in the standard practice of medicine. Persons between 3 and 100 years of age diagnosed with or sus

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📋 Eligibility rules (as published)
* INCLUSION CRITERIA: Age 3-100 years. Access to a primary medical care provider outside of the NIH. Ability to give informed consent. Clinical evidence suggestive of a filarial infection EXCLUSION CRITERIA: Although pregnant or nursing women can be enrolled, they will be excluded from receiving treatment while pregnant or breastfeeding Less than 3 year of age; greater than 100 years of age Any condition that the investigator feels put the subject at unacceptable risk for participation in the study
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What it tests

  • Diethylcarbamazine
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Where

1 site
National Institutes of Health Clinical Center
Bethesda, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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