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Magnetic Resonance Spectroscopy Studies of Cardiac Muscle Metabolism

Recruitingn/aAges 18 Years - anyAllJohns Hopkins University
NCT00181259 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The metabolism of the heart provides the chemical energy needed to fuel ongoing normal heart contraction. Magnetic resonance spectroscopy is a technique used in a MRI scanner that can be used to measure and study heart metabolism directly but without blood sampling or obtaining tissue biopsies. One of the hypotheses this study aims to investigate is whether energy metabolism is reduced in heart failure and whether that contributes to the poor heart function.

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📋 Eligibility rules (as published)
Inclusion Criteria: * age \> 18 years * Healthy subjects: no history of heart disease * Dilated cardiomyopathy: history of heart failure, ejection fraction (EF) \<40% * Left ventricular hypertrophy: wall thickness \>1.2cm * Coronary artery disease: \>50% coronary lesion or positive stress test Exclusion Criteria: * contraindication to MRI
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What it tests

  • Not listed
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Where

1 site
Johns Hopkins Medical Institutions
Baltimore, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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