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Effects of Oncological Treatment During Pregnancy on Mother and Child

Recruitingn/aAges 18 Years - anyFemaleUniversity Hospital, Gasthuisberg
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In plain words

What the trial is, and whether it could suit you

The researchers aim to investigate the outcome (overall survival) of mothers who are diagnosed and/or treated for cancer during pregnancy. Furthermore they want to test the hypothesis that children who were exposed to cancer or cancer treatment (cytotoxic drugs, radiation therapy, targeted therapy,...) develop normally (neurologic and cardiologic examination).

Sign in to get the eligibility rules as simple questions to take to your doctor.

📋 Eligibility rules (as published)
Patients do not need to participate in both; however, preferentially both study parts should be performed. \*\*\*\*\*\*\*\*\*\*\*\*\*\*Part I: Pregnancy, delivery and maternal health\*\*\*\*\*\*\*\*\*\*\*\*\*\* Patients must meet the following inclusion criteria: * Histologically proven cancer in association with a pregnancy (during pregnancy or cancer dagnosis within 5 years after pregnancy) * \> 18 years of age, premenopausal * Patients who have given their signed and written informed consent to participate in the trial after fully understanding the implication of the protocol * Women receiving any cytotoxic drug or radiation therapy during pregnancy are allowed for the assessment of the maternal and fetal outcome (Part II). Exclusion Criteria: * Mentally disabled or significantly altered mental status that would prohibit the understanding and giving of informed consent \*\*\*\*\*\*\*\*\*\*\*\*\*\*Part II: Follow-up of children\*\*\*\*\*\*\*\*\*\*\*\*\*\* Inclusion Criteria: \- Children that were prenatally exposed to cancer of cancer treament. Informed Consent is asked from parents. From the age of 12 years, informed assent is additionally asked from the child. After the age of 18 years, informed consent is solely asked of the offspring. Exclusion Criteria: * Mentally disabled or significantly altered mental status that would prohibit the understanding and giving of informed consent
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What it tests

  • Not listed
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Where

33 sites
Cooper University Hospital (2015-ongoing)
Camden, United States
Instituto Alexander Fleming
Buenos Aires, Argentina
Universitätsklinik für Frauenheilkunde und Geburtshilfe (retrospective 2016-2018)
Graz, Austria
UCL Brussels (2013-ongoing)
Brussels, Belgium
UZ Gasthuisberg, Katholieke Universiteit Leuven (2004-ongoing)
Leuven, Belgium
University Hospital Ostrava (2018-ongoing)
Ostrava, Czechia
3rd medical faculty of Charles University (2010-ongoing)
Prague, Czechia
Copenhagen University Hospital (2015-ongoing)
Copenhagen, Denmark

…and 25 more on ClinicalTrials.gov.

🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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