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Biliary Atresia Study in Infants and Children

Recruitingn/aAges 6 Months - 20 YearsAllArbor Research Collaborative for Health
NCT00345553 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Little is known about the factors that cause biliary atresia nor the factors that influence disease progression. The purpose of this study is to collect the pertinent clinical information, genetic material and body fluid samples to enable investigators to address the following aims: To identify the gene or genes implicated in the etiology of BA; To characterize the natural history of the older, non-transplanted child with BA.

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. Participants need to have a confirmed diagnosis of BA determined by chart review including review of pertinent diagnostic biopsy reports, radiologic reports and surgical reports (if surgery was performed). 2. Participants need to be \>6 months of age up to and equal to the age of 20 (participants enrolled at 20 years of age will have one visit). 3. Participants with their native liver. 4. Parent, guardian or participant (if 18 years of age or older) is willing to provide informed consent and, when appropriate, the participant is willing to assent. Exclusion Criteria: 1. Currently participating in the ChiLDReN study PROBE. 2. Inability to confirm original diagnostic evaluation of biliary atresia. 3. Inability or unwillingness of family or participant to participate in all scheduled visits. 4. History of liver transplantation.
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What it tests

  • Not listed
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Where

16 sites
Children's Hospital of Los Angeles
Los Angeles, United States
University of California at San Francisco
San Francisco, United States
Children's Hospital Colorado
Aurora, United States
Children's Healthcare of Atlanta - Emory University
Atlanta, United States
Ann & Robert H. Lurie Children's Hospital of Chicago
Chicago, United States
Riley Children's Hospital
Indianapolis, United States
Johns Hopkins School of Medicine
Baltimore, United States
Washington University School of Medicine
St Louis, United States

…and 8 more on ClinicalTrials.gov.

🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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