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Barrett's Esophagus Related Neoplasia (BERN) Project

Recruitingn/aAges 18 Years - anyAllMidwest Biomedical Research
NCT00590239 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

* The use of high resolution endoscopy (HRE), narrow band imaging (NBI) and chromoendoscopy increases the detection rates of Barrett's esophagus (BE) and early neoplasia. * Endoscopic mucosal resection (EMR) will improve the accuracy for detection of dysplasia/early neoplasia. Specific Aim 1 - To create a video-atlas of non-dysplastic and dysplastic/early neoplastic lesions in patients with BE. This will be used for training purposes and to assess learning curve associated with these new technologies. Specific Aim 2 - To create a standardized classification system for the mucosal and vascular patterns observed in patients with BE. Specific Aim 3 - To determine the interobserver agreement using the video-atlas for the mucosal and vascular patterns classification agreed upon. Specific Aim 4 - To determine the endoscopic detection rate of esophageal cancer or precancerous lesions remove

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📋 Eligibility rules (as published)
Inclusion Criteria: * 18-80 years * Patients must be able to provide written informed consent * Patients referred for endoscopy for screening/surveillance of BE or for endoscopic treatment of BE with early mucosal neoplasia Exclusion Criteria: * Current use of aspirin, non-steroidal anti-inflammatory agents(NSAIDs),or chronic anticoagulants that cannot be discontinued prior to the procedure. * Inability to provide written informed consent * Significant thrombocytopenia or coagulopathy * Any significant co-morbid condition that would prevent the safe administration of conscious sedation
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What it tests

  • Not listed
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Where

1 site
Kansas city VA Medical center
Kansas City, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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