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International Pediatric Adrenocortical Tumor Registry

Recruitingn/aAges any - 21 YearsAllSt. Jude Children's Research Hospital
NCT00700414 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study aims to collect demographic and medical information including detailed family history of cancer of children and adolescents with adrenocortical tumors in order to learn more about the clinical and epidemiological aspects, treatment modalities, and outcome of patients with this rare disease, worldwide. In addition, investigators at St. Jude Children's Research Hospital (SJCRH) plan to perform molecular studies of tumor cells aimed to clarify the role of the TP53 gene and other genetic pathways in these tumors. They aim to obtain relevant biological material from participants with adrenocortical tumor (ACT), their biological parents, and relatives for determination of the TP53 germline status, molecular studies of the TP53 gene, and other molecular pathways.

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📋 Eligibility rules (as published)
STRATIFICATION ASSIGNMENT: * Stratum A: participant suspected or confirmed diagnosis of adrenocortical tumor (ACT) * Stratum R: relative of participant with ACT and TP53 mutation who has diagnosis of malignancy * Stratum P: biological parent of participant with ACT Inclusion Criteria - Stratum A (participant with ACT): * Age ≤ 21 years old at diagnosis * Suspected or confirmed diagnosis of adrenocortical tumor (adenoma, carcinoma or undefined histology). * Signed informed consent Inclusion Criteria - Stratum R (relative): * Any age * Diagnosis of malignant tumor * Signed informed consent Inclusion Criteria - Stratum P (parent): * Biological parent of Stratum A participant
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What it tests

  • Not listed
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Where

5 sites
Stanford University
Stanford, United States
All Children's Hospital/St. Petersburg Hospital
St. Petersburg, United States
The Children's Medical Center
Dayton, United States
St. Jude Children's Research Hospital
Memphis, United States
Cook Children's Medical Center
Fort Worth, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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