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โ† Trials
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Genetic Variants and Susceptibility to Diseases of Prematurity in Very Low Birth-Weight Infants

Recruitingn/aAges any - anyAllMedical College of Wisconsin
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In plain words

What the trial is, and whether it could suit you

The purpose of this study is to determine if sequence variations in genes involved in the development and function of vulnerable organs increases susceptibility to chronic lung disease (CLD) and other diseases affecting premature infants, such as necrotizing enterocolitis (NEC), sepsis, patent ductus arteriosus (PDA) and intraventricular hemorrhage (IVH). The study will also determine whether measurement of certain biomarkers in serum will identify infants who will develop these complications of prematurity. Previous studies from this institution and others have identified genetic variants in some genes, such as toll like receptor genes are associated with higher risk of CLD or NEC. The interaction of these variants with other gene variants that can influence the risk of these diseases remains unclear.

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Infants born weighing less than 1500 grams Exclusion Criteria: * Infants born with congenital heart disease (other than patent ductus arteriosus) * major congenital anomalies of the GI tract, respiratory tract, or kidneys
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What it tests

  • gene variations
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Where

1 site
Children's Wisconsin
Milwaukee, United States
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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