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Database Registry for Neural Network Biomarkers in Psychosis

Recruitingn/aAges 18 Years - 60 YearsAllUniversity of Texas Southwestern Medical Center
NCT01409109 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Several observations have been made with magnetic resonance imaging (MRI) that characterize brain connections and brain function in individuals with schizophrenia and other mental disorders. For example, research investigating schizophrenia focuses on the dysfunction of connections within and between the medial temporal lobe and the prefrontal cortex as well as other pertinent brain regions. This database registry will allow for the collection of clinical interview data, behavioral data, blood, magnetic resonance imaging (MRI) data, and functional magnetic resonance imaging (fMRI) data on individuals with and without mental disorders to better understand how connections in the brain and various brain regions function differently while volunteers perform various cognitive tasks. This is an observational study that is being conducted to collect data and place it in a registry for current a

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📋 Eligibility rules (as published)
Inclusion Criteria: Volunteers with Schizophrenia or other mental illness * Diagnostic and Statistical Manual of Mental Disorders, 4th Edition, Text Revision (DSM-IV-TR) diagnosis of Schizophrenia or Schizoaffective disorder * Competent to give informed consent * All races and ethnicities * Eyesight corrected to 20-40 or better * Able to read, speak, and understand English Healthy volunteers * No past or current severe mental illness * All races and ethnicities * Eyesight corrected to 20-40 or better * Able to read, speak, and understand English Exclusion Criteria: Volunteers with schizophrenia or other mental illness * Diagnosis of an organic brain disease * Diagnosis of DSM-IV-TR alcohol or substance abuse within the last month or DSM-IV-TR alcohol or substance dependence within the last three months * Serious, unstable medical illness * History of serious head injury * Pregnant women Healthy volunteers * History of psychiatric illness * Current use of psychoactive drugs excluding nicotine and caffeine * Diagnosis of an organic brain disease * Serious, unstable medical illness * History of serious head injury * Pregnant women
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What it tests

  • Not listed
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Where

1 site
University of Texas Southwestern Medical Center
Dallas, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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