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Hormonal, Metabolic, and Signaling Interactions in PAH

Recruitingn/aAges any - 90 YearsAllVanderbilt University Medical Center
NCT01884051 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Our hypothesis is that optimal treatment of the dysfunctional metabolic pathways which underlie PAH will improve pulmonary vascular function and consequences of the disease.

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📋 Eligibility rules (as published)
Inclusion Criteria: Project 1 Inclusion: 1. Diagnosis of IPAH (idiopathic pulmonary arterial hypertension), HPAH (heritable pulmonary arterial hypertension), or APAH (associated pulmonary arterial hypertension), family members of affected persons 2. Age 0-90, age 12-90 for skin biopsy Exclusion: 1. Other diagnosis 2. Age greater than 90, age less than 12 or greater than 90 for skin biopsy Project 2 Inclusion: 1. Diagnosis of IPAH, HPAH, or APAH, family members of affected persons 2. 0-90 3. Subjects with reasonably easy access to clinic for blood collection and other testing 4. Subject able to tolerate fasting state prior to sample collection and EndoPAT (endothelial function assessment) testing Exclusion: 1. Other diagnosis 2. 0-90 3. Subjects with difficulty reaching clinic for blood collection and other testing 4. Subjects unable to tolerate fasting state Project 3 Inclusion: 1. Diagnosis of IPAH, HPAH, or APAH, family members of affected persons 2. 7-90 Exclusion: 1. Other diagnosis 2. Age less than 7 or greater than 90 \- Exclusion Criteria: \-
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What it tests

  • Not listed
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Where

1 site
Vanderbilt University Medical Center
Nashville, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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